Actinobacillus indolicus: EXH44_09680
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Entry
EXH44_09680 CDS
T05940
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
aio
Actinobacillus indolicus
Pathway
aio00260
Glycine, serine and threonine metabolism
aio00261
Monobactam biosynthesis
aio00270
Cysteine and methionine metabolism
aio00300
Lysine biosynthesis
aio01100
Metabolic pathways
aio01110
Biosynthesis of secondary metabolites
aio01120
Microbial metabolism in diverse environments
aio01230
Biosynthesis of amino acids
Module
aio_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
aio_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
aio_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
aio00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EXH44_09680 (thrA)
00270 Cysteine and methionine metabolism
EXH44_09680 (thrA)
00300 Lysine biosynthesis
EXH44_09680 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EXH44_09680 (thrA)
Enzymes [BR:
aio01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EXH44_09680 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EXH44_09680 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
DUF1131
TetR_C_5
Motif
Other DBs
NCBI-ProteinID:
QBQ64471
UniProt:
A0A4P7CMS5
LinkDB
All DBs
Position
complement(1955287..1957731)
Genome browser
AA seq
814 aa
AA seq
DB search
MRVLKFGGTSLANPERFLQAAEIIEKAHLADQAAGVLSAPAKITNHLVAIVDKAQAGESY
ESHLTEATDIFNNIINGLYAVNHNFDREGLSTFIKAELDDICNIASEAAKNKFCPDNIGA
TVHSRGEKLSIAMMKAWFEAKGYEVTRIDPVEKLLAHGSYLESSVDITESTKRIEALSIP
KKNVVLMAGFTAGNEQGELVLLGRNGSDYSAACLAACLKADVCEIWTDVDGVYTCDPRLV
PDAICLESMSYQEAMELSYFGAKVIHPRTIGPLVPLNIPCLIKNTHNPEAKGTIIDGNVV
NDNLKVKGITNLDNVAMFNVSGSGMQGMVGMAARVFTAMSQAGISVNLITQSSSEYSISF
CVPVKAVEKALSALNTTFSQELKDGSLDPVEVIKDLSIVSVVGDGMRTAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPLNKAIEAVKATHKALFNNKKVVDVFLVGVGGVGGEL
IEQIKTQKEYLAKKDIEIRVCALANSNKMLLNENGLSLDNWRADLESATQPSDFDVLLSF
IKLHHVVNPVFVDCTTAQSVANLYARALKEGFHVITPNKKANTSSYAYYQEMRENARQSQ
HKFLYETNVGAGLPVIENLQNLLAAGDEVEKFEGILSGSLSFIFGKLEEGSSLSEATTIA
KEKGFTEPDPRDDLSGQDVARKLLILARECGYPLELEDIEVEGVLPKGFSEGKTAAEFLA
MLPELDAEFAKRVEKATACGNVLRYVGSIENGKCRVAIKEVNGDDPLYKVKNGENALAFY
TRYYSPIPLLLRGYGAGNDVTAAGIFADILRTLK
NT seq
2445 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttctaaaatttggaggcacatctttagccaatccagaacgctttctacaagca
gccgagatcatcgaaaaagcacatttggcagatcaagccgcaggcgtcctatccgctcct
gctaaaattactaaccatcttgtcgccattgtcgataaagcccaagcaggcgaatcctac
gaatctcatctcaccgaagccaccgacattttcaacaacatcatcaacggattatatgcc
gtcaatcacaatttcgaccgtgaaggattaagtacctttatcaaagcggaattagatgac
atctgcaacattgcatctgaagccgcaaaaaataaattctgtccagataatatcggcgca
acagtacatagccgtggggaaaaattgtcgattgcgatgatgaaagcgtggtttgaagcg
aaaggttatgaagtcactcgcattgatcctgtcgaaaaattattagcacacgggagctat
ttagaatcttctgtggacattactgaatccaccaaacgcattgaagccctttctattcca
aagaaaaatgtggtgttaatggcgggctttaccgcaggtaatgagcaaggcgaattagtg
ttacttggacgaaacggttcagactactctgcagcctgtttagccgcttgcttaaaagca
gatgtatgcgaaatttggacggacgtggacggtgtttatacttgcgaccctcgtttagtg
ccagatgcgatctgcttagagtctatgagctatcaagaagcaatggagctttcttacttt
ggtgcgaaagtaatccaccctcgcactattggcccgttagtgccgttaaatatcccgtgc
ttaattaaaaatacccataatccagaagccaaaggcacgatcattgacggtaatgtggtc
aacgataacttaaaagtaaaagggatcacaaatcttgataatgtggcaatgttcaacgta
tcaggttcaggtatgcaaggcatggttggtatggcagcacgtgtgtttaccgcaatgtcg
caagcgggtatttccgtgaacttaattacacaatcttcttctgaatatagtattagcttc
tgtgtgccagtaaaagcggttgaaaaagcattatcagcattaaatactaccttttcacaa
gaattaaaagatggctcgctcgatcctgtagaagtgattaaagatctctctattgtttct
gtagttggtgatggtatgcgtaccgccaaagggattgctgctcgcttcttttctgcatta
gctcaagcaaatatcagcattgtagcgattgcgcaaggttcatcagagcgttcaatctct
gccgttgtgccattaaataaagcaattgaagcggttaaagcaacgcacaaagcgctattc
aataacaaaaaagtggtcgatgtctttttagtgggtgttggcggtgttggtggtgagttg
attgagcagatcaaaacacagaaggagtacctcgcaaaaaaggacattgaaatccgtgtg
tgtgccttagccaactcgaacaaaatgttactcaatgaaaacggtttaagcttggataac
tggcgtgcggatttagaatcagcgacacagccgtctgactttgatgtattgctttcattc
attaagttacaccacgttgtcaatcctgtttttgtggattgcactacagctcagtctgtg
gcaaatctttatgctcgagcattaaaagaaggcttccacgtgattacgccaaataagaaa
gcgaatacgtcaagctatgcttattatcaagaaatgcgtgaaaatgcccgtcaaagccaa
cataaattcctatatgaaacgaatgtgggtgcaggtttgccagtgattgaaaacttgcaa
aacttgctagctgcaggtgatgaagtcgagaaatttgaagggattttatctggttcactc
tcttttattttcggtaaattagaagaaggttcaagtttgtctgaagcaaccaccattgcc
aaagagaaaggctttactgaacctgatccacgtgatgatttatcagggcaagatgtcgct
cgtaaactcttaattttagcgcgtgagtgtggctacccattagagctggaagatattgaa
gtggaaggcgttttaccaaaaggtttctctgaaggtaaaactgcagcggaatttttggcg
atgttgccagaacttgatgcagaatttgcaaaacgtgttgaaaaagcaaccgcttgtgga
aatgtgttacgctatgtaggttccattgaaaacggtaaatgccgtgtggcgatcaaagaa
gtgaacggtgatgatccgctttataaagtgaaaaatggtgaaaacgcccttgcgttctac
actcgctattacagcccgattccgcttcttttacgtggttacggtgcaggtaacgatgtg
accgcagcaggtatttttgcggatattttgcgtacgttaaaataa
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