Actinomyces israelii: NCTC12972_00708
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Entry
NCTC12972_00708 CDS
T06659
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
air
Actinomyces israelii
Pathway
air00010
Glycolysis / Gluconeogenesis
air00020
Citrate cycle (TCA cycle)
air00620
Pyruvate metabolism
air00785
Lipoic acid metabolism
air01100
Metabolic pathways
air01110
Biosynthesis of secondary metabolites
air01120
Microbial metabolism in diverse environments
air01200
Carbon metabolism
air01210
2-Oxocarboxylic acid metabolism
Module
air_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
air00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NCTC12972_00708 (aceE)
00020 Citrate cycle (TCA cycle)
NCTC12972_00708 (aceE)
00620 Pyruvate metabolism
NCTC12972_00708 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NCTC12972_00708 (aceE)
Enzymes [BR:
air01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NCTC12972_00708 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
VEG53617
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Position
1:complement(794063..796816)
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AA seq
917 aa
AA seq
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MSPTSDSAPLIDGLLSKVTDNDPEETKEWRDSLDALIKEKGAPRARFILLSMLAEARRKN
VAVPAQTATPYVNTINVEDEPYFPGDEDTERTYRRWLRWNAAVMVTRAQRPGVAVGGHIS
SYASTATLYEVGMNHFFRGKDHPGGGDHVFFQGHASPGNYARAFIEGRLTETDLDGFRQE
YSHPEGGRGMPSYPHPRRMEDFWEYPTVSMGLGPAEAIYQAWFDKYLQGAGIKDTSQQHT
WAFLGDGEMDEPESRGMIHLAAGQQLDNLTFVINCNLQRLDGPVRGNGKIIQELEAEFKG
AGWNVIKVIWGRGWDQLLAADKDHALEHLMMETLDGDYQAFKANDGAYVREHFFNRDPRT
AALVKDWTDEQIWALQRGGNDYRKMYAAYKAAMEHKGQPTVILAHTVKGYMLGSHFAGRN
ATHQMKKLSLDDLKGLRDRLRIPITDEQLEANPKLPPYYRPAADDPALLYMLERRRQLGG
FVPERRDHGKELELPGDKAYDILKSGSGNQEVATTMAFVRLLKELIKEKGIGRRIVPIVP
DESRTFGLESLFPTKKIYNTQGQNYTPVDADMMLSYRESTSGQLMHTGINEAGSAALFQV
VGTSYATHGEPMIPVYIFYSMFGFQRTADQFWAAGDQLARGFIMGATAGRTTLAGEGTQH
MDGHSPLISATNEAVVTYDPAYAYEIRHIVRDAIERWYGPDSGRNRDIMYYLTIYNEPIV
QPAEPENVDVEGILKGLYKLDDAPAGDGPEVTLLASGVGVPWIRQARELLLNDWGVRAST
WSVTSWNELRREALAVEKANFLSGDAAGQVPYLTRQLSQAQGPFIATSDFDHLVQDQIRA
WVPGDFHTLGADGFGFSDTRPAARRFFLIDAHSVAVKALQALVRQGRLDRSVLEQALARY
ELENIHAGSSGSTGGDA
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccagcgactctgctccacttatcgacggactcctaagcaaggtcaccgac
aacgaccccgaggagaccaaggagtggcgcgactcgctcgacgccctcatcaaggagaag
ggcgcaccccgggcccgcttcattctcctgtctatgctcgctgaggcgcgccgcaagaac
gttgccgtgcccgcccaaacggccaccccctacgtcaacaccatcaacgtggaggacgag
ccctacttccccggcgacgaggacaccgagcgcacctaccgccgctggctgcgttggaac
gcggcagtcatggtgactcgcgcccagcgccccggcgtcgccgtcggtggccacatttcc
tcctacgcctccaccgccaccctctacgaggtcggcatgaaccacttcttccggggcaaa
gaccaccccggcggcggtgaccacgtttttttccagggccacgcctcccctggcaactac
gcccgtgccttcatcgaggggcgtttaacggaaactgatctggacggattccgccaggag
tactcccacccagagggcggccgcggcatgccctcctacccacacccgcgccgtatggag
gacttctgggagtaccccaccgtctccatgggcctgggtcctgccgaggccatttaccag
gcctggttcgacaagtacctgcagggcgcaggcattaaggacacttctcagcagcacacc
tgggccttcctgggtgatggcgagatggacgagcccgagtcgcgcggcatgatccacctg
gctgccggccagcagttggacaacctgacctttgtcatcaactgcaacctgcagcgtcta
gacggtccggtgcgtggaaacggcaagatcatccaggagctcgaggccgagttcaaaggt
gccggttggaacgtcatcaaggtgatctggggtcgtggctgggaccagctgcttgccgca
gacaaggaccacgccctggagcacctcatgatggaaactctcgacggcgattaccaggcc
ttcaaagctaacgacggcgcctacgtgcgcgagcacttcttcaaccgcgacccacgcacc
gccgcactggtcaaggactggaccgacgagcagatctgggccctgcaacgcggtggcaac
gactaccgcaagatgtacgccgcctataaggctgctatggagcacaagggccagcccacc
gtgatcctggcgcacactgttaagggctacatgctggggtcgcacttcgccggccgcaat
gccacccaccagatgaagaagctgtcgctggatgaccttaagggcctgcgcgaccgcctg
cgcatcccgatcacagatgagcagctagaggccaatcccaagctgccgccctactaccgt
cccgcagcggacgacccagccctgctgtacatgctggagcgacgccgtcagctcggtggt
tttgtgcccgagcggcgcgatcacggcaaggagttggaactgcctggggacaaggcctac
gacatcctcaagtctggttctggcaatcaggaggtggccaccacgatggctttcgtgcgc
ctcctcaaggagctcattaaggagaagggtatcgggcgtcgtatcgtgccgattgtcccc
gatgagtcccgcaccttcggcctggagtcgctcttccccaccaagaagatctacaacacc
cagggccagaactacacgccggtggacgctgacatgatgctgtcctaccgggagtccacc
tccggacagctcatgcacaccggcatcaacgaggctggttccgctgcgctattccaggtg
gttgggaccagctacgccacgcacggcgagccgatgatccccgtctacatcttctactcg
atgttcggcttccaacgcactgcggaccagttctgggctgccggtgaccagctggcacgc
ggcttcattatgggtgccactgcgggccgcaccaccttggcaggtgagggcacccagcac
atggacggccactcgccgctgatctccgccacaaacgaggcggtggtaacttatgacccg
gcttatgcctacgaaatccgccacatcgtgcgcgatgccatcgagcgctggtacggcccc
gactccggccgcaaccgcgacatcatgtactacctgaccatctacaacgagcccatcgtc
cagccggctgagccggagaatgtggacgttgagggcatcctcaagggcctttacaagctc
gacgacgcccccgccggggacggaccagaggtcacgctgctggcctccggcgtcggcgtg
ccgtggatccgtcaggcccgcgagctgctgctaaacgactggggcgtgcgcgcttctact
tggtcggtcacctcctggaacgagctgcgccgtgaggccctagctgtggagaaggccaat
ttcctttctggagatgctgctggccaggtcccctacctgacgcgccagctctcgcaggcc
caggggcccttcatcgccaccagcgacttcgatcacctggtccaggatcagatccgcgcc
tgggtgcccggtgacttccacaccctgggtgcggacggctttggcttctccgacacccgc
ccggcagcccgccgcttcttcctaatcgacgcacactccgtggcggtcaaggccctgcag
gccttagtgcgtcagggcagactggaccgctcagtgctggagcaagcgctggcccgttac
gaactggagaatatccacgctggctcctcaggttctacgggtggcgacgcctga
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