Artibeus jamaicensis (Jamaican fruit-eating bat): 119058337
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Entry
119058337 CDS
T07223
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ajm
Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm00010
Glycolysis / Gluconeogenesis
ajm00020
Citrate cycle (TCA cycle)
ajm00620
Pyruvate metabolism
ajm00785
Lipoic acid metabolism
ajm01100
Metabolic pathways
ajm01200
Carbon metabolism
ajm01210
2-Oxocarboxylic acid metabolism
ajm04066
HIF-1 signaling pathway
ajm04922
Glucagon signaling pathway
ajm05230
Central carbon metabolism in cancer
ajm05415
Diabetic cardiomyopathy
Module
ajm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ajm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119058337 (PDHA1)
00020 Citrate cycle (TCA cycle)
119058337 (PDHA1)
00620 Pyruvate metabolism
119058337 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119058337 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119058337 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119058337 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119058337 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119058337 (PDHA1)
Enzymes [BR:
ajm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119058337 (PDHA1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
119058337
NCBI-ProteinID:
XP_037013385
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYKMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTYTRGLSVREILAELTGRRGGCAKGKGGSMHMYARNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcaggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaag
tgtgatcttcaccggctggaggagggcccccctgtcacaacggtgctcaccagggaggac
gggctcaaatactacaagatgatgcagactgttcgccgaatggagttaaaggctgatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaagctggcataaatcccacagaccatctgatcaccgcctatcgggct
catggcttcacctatactcgtgggctttctgtacgagaaattctcgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcaatgcatatgtatgccagaaatttc
tacgggggcaatggcatcgttggagctcaggtgccactgggagcggggattgctctggcc
tgcaagtataatgggaaagacgaggtctgtttgaccttatatggtgatggagctgctaat
caggggcagatatttgaagcttataacatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatggaatggggacatctgttgagagagcagcagccagcact
gattactacaagagaggtgacttcattcctgggctgagggtagatggaatggatgtcttg
tgtgtccgggaggcaacaaagtttgcagcagcccattgtagagctggaaaggggcccata
ctgatggagctgcagacctaccgttaccacggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagcaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaaccttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaagacgctgcccaatttgcaacagctgatcctgagccacct
ttggaagaactaggctatcacatctactccaatgatccaccttttgaagttcgtggtgca
aatcagtggatcaagtttaagtctgtcagttaa
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