Austrofundulus limnaeus (annual killifish): 106529092
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Entry
106529092 CDS
T06063
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
alim
Austrofundulus limnaeus (annual killifish)
Pathway
alim04217
Necroptosis
alim04620
Toll-like receptor signaling pathway
alim04621
NOD-like receptor signaling pathway
alim05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
alim00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
106529092 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
106529092 (tyk2)
04621 NOD-like receptor signaling pathway
106529092 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
106529092 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
alim01001
]
106529092 (tyk2)
Enzymes [BR:
alim01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
106529092 (tyk2)
Protein kinases [BR:
alim01001
]
Non-receptor tyrosine kinases
JAK family [OT]
106529092 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
Kdo
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
106529092
NCBI-ProteinID:
XP_013879887
UniProt:
A0A2I4CIS9
LinkDB
All DBs
Position
Unknown
AA seq
1157 aa
AA seq
DB search
MSVRGWFGLSRARTLQGSNGPPQCEGIHVYMFWTKEGERYLTHXSGDVTAEELCILAAEA
VGITPLCHVLFALYDLQQQCWYSPNHVFSPKMDSGVILHYCMRFYFRNWHGLNDKEPNVF
RYALKSDQTGSPLLDITSLEYLFAQAKYEFVNEVAQMEDIESEEELSRFKNESLGMAVLH
LSHLAIQKNSTLQEVAKKHSFLECIPVSFAQHISRDNFLTKIRIRRVFSDFVRTFQQHTV
DIGHLGAQEIMYKYISTLEHLAPSFGTEAFSVSDWKLTEHSNGSSSYTRCDGDLRKPCGA
EATHEIMVSGTKGIHWRKLSQKKQTDPRLRNNYLNLSKKSKQNSSEANGESHDDWEFFCD
FPEITVIDINESNVRISTQLNQCLEVEMRSSQEACSFISLLDGYYRLTADAHHYLCREVA
PARVVLSEANLLHGPMHDDFVLHKLKKEAAEVGTFLVRWSALDYHRIILAVLNRSENDSA
PSHKQFRIQQKGSVFVMEGWDREFSSVKELTDSLKTFVLKSGSDNFTVRKCCLPKQGEIS
NLLVKRQGGDLRTNSGSLELNLTQLRFHQIKDKEITQEGHLGRGTRTNIYLGRLCVAGEF
SNNNVSKMIRVVLKVLDQSHKDIALAFFETASLMSQLSHSHLVFVHGVSVKGSENIMVEE
YVEFGPLDVFLRRAGDVIKAEWKLVVSLQLASALTYLETKRLVHGNVCAKNILVARRGIE
PGTSPFVKLSDPGIALNVLTREERLDRIPWIAPECVDSDAPIGNAADQWSFGVTLLEICN
NGILPMSSSTLSEKERFYQQKGRLAEPSSQDLSEFVSMCLTYDPDARPSFRTILRELTEI
IKKNPGIFPFVTLPPPDPSSFQKRYMKKMRDLGEGHFGKVTLYLYDPSNDGTGELVAVKA
LKQEGNSPEGWMKEIDILKSLYHLNIVKYKGCCTEPGRQQVQLIMEYLPQGSLRDYLPKH
KASVSQCLMFSQQICQGMEYLHSKRYVHRDLAARNVLVENNRLVKIGDFGLTKYIPEGEI
YYRVHENGDSPVFWYAIECLKEQKFSFASDVWSFAVTLYEILTNCDHRRSPPTMFFEMTQ
ESDGQMNLMALLNLLEKNRRLPCPQHCPREVEYIMKQCWSTSPADRPTFEELVKKFEEIR
KTYDWQFSTNFPMSQIC
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtgagaggatggtttgggctttcaagagcgcggacccttcaaggctcgaatgga
cccccccagtgcgagggcattcatgtttacatgttctggactaaagaaggggagagatat
ttgactcacrcaagcggagatgtcacagcggaggagctgtgcatcttggccgcagaggct
gtaggaataactcccctatgtcacgtgctgtttgcgttgtacgatctacaacagcagtgc
tggtacagtccaaatcatgttttcagtccaaaaatggactccggtgtaatacttcactac
tgtatgaggttttactttcggaactggcatggactaaacgacaaagagccaaacgtattc
cggtatgctctcaaatcagatcagacgggctctcctctgcttgatatcacatccttggag
tatttgtttgcgcaggccaaatatgagtttgtgaatgaagttgcgcaaatggaggacaty
gagtcagaggaggaactaagtcgcttcaaaaatgagagtctgggcatggctgtgcttcac
ctctcacacctcgcaatacagaagaactctacattacaggaagtggctaaaaaacatagc
ttcctagaatgcattccagtgtctttcgcccaacacatatccagggataactttctgact
aaaatcaggatccggcgggtgttttccgattttgtacggaccttccagcagcacacggtg
gatatcggacatctgggtgcgcaggagatcatgtataagtacatctctaccctcgaacac
ttggctccgtcttttggcacggaggctttctcagtaagcgactggaaactgactgaacac
agcaacgggagcagctcttacacgcgctgcgacggcgacttaagaaaaccctgcggtgct
gaggccacgcatgaaataatggtgtctggcactaaggggatccactggaggaagttgagc
cagaagaagcagacggacccccgtctcaggaacaattatttgaacttgtcaaagaaatcg
aaacaaaactccagcgaagcaaacggggagagtcacgacgactgggagttcttctgtgat
ttcccagaaataactgtcatagacataaacgagtctaatgtgcgcattagcactcagctc
aatcaatgcytggaggtagagatgagatccagccaagaggcctgctccttcatctccctc
ctcgatgggtactacagactgactgcggacgcccaccactacctctgtcgagaagtggct
cccgccagggtggtgttgagcgaagcgaatctgctgcacggaccgatgcatgatgacttc
gtgctgcacaagctaaaaaaagaggcagccgaggtcggaacgttcctcgttcgatggagc
gccctcgactatcaccgcatcatccttgctgtgctgaacagaagcgagaacgactcggcg
ccgagccacaagcagtttcgtatccagcagaagggttctgtgttcgtcatggagggctgg
gaccgagagttctccagygtgaaggagctcacagacagcctcaaaaccttcgtgctcaag
tccggttcggacaactttacggtcagaaaatgctgtttgccgaaacaaggagaaatatcc
aacctgctggtgaaaaggcagggtggtgacctccgcaccaactccgggtctttggagctg
aacctgacgcagctccgcttccaccagattaaggacaaagaaatcacacaggaaggacat
ttgggtcgtggcaccagaaccaacatctatttaggacgcttgtgtgtggcaggggagttc
agcaacaacaacgtttctaaaatgattcgtgtggttctgaaggttttagaccaaagccat
aaagatattgctctggcattttttgaaactgcaagtctcatgagccagttatcccacagt
catctggtgtttgtgcacggtgtatcagtcaaaggatctgaaaacatcatggtggaagaa
tatgtggagtttgggcctttggacgtcttccttcgccgagcaggggacgtcatcaaagcg
gagtggaaattggttgtttccttacaacttgcgagtgccctcacttatcttgagacgaaa
cgcctggttcatgggaacgtctgtgccaagaatattctggtggcaaggcggggaatagaa
cctggcacttcaccttttgtcaagctgagtgatccaggaattgctcttaacgtcctcaca
agagaagaacgtttggaccggatcccgtggatcgccccmgaatgcgtcgacagtgacgct
cctatcggcaacgctgctgaccagtggagctttggcgtcacgctgcttgaaatctgcaac
aatggcatccttcccatgagcagcagcacgttgtccgagaaagagcgtttttatcagcaa
aagggtcgtctcgccgaaccgtcctctcaggacctgtctgagttcgtcagcatgtgtttg
acatacgaccctgacgcaaggccttcctttcgtaccatcctcagrgagctcacagagatc
ataaagaaaaatccyggcatatttcccttcgtcacgctcccaccgcctgaccccagcagt
ttccagaagcgctacatgaaaaagatgcgggatttaggcgagggacactttggaaaggtg
acgctgtacctgtatgaccccagcaacgacggcactggggagcttgtggcagtgaaagcc
ttgaagcaagaaggtaactcgcccgagggctggatgaaggagattgatatcctgaaatcc
ctctaccacctcaacattgtcaagtacaagggctgctgcactgagccaggaagacaacag
gtccagctgataatggagtaccttccccaggggagcctgcgggattatcttcctaaacat
aaagccagcgtgtcccagtgcctcatgttttctcagcagatctgtcagggaatggagtac
ttgcactcaaagcgctatgtgcatcgagatctggctgcccgcaacgtcttggtggaaaac
aaccgtttggtaaagatcggagacttcggcctgaccaaatacatccctgagggagagatc
tactacagagttcatgaaaacggagacagccccgtgttctggtatgctatcgagtgcttg
aaggagcaaaagttttcttttgcgtccgacgtttggtctttcgcagttactctgtatgag
atcctgaccaactgtgaccatcgcagaagccctccaacaatgttctttgaaatgacgcag
gaatctgacggacagatgaacttgatggctcttttaaacctgttagaaaaaaaccggagg
ttaccatgtccccagcactgtccacgtgaggttgagtacattatgaagcagtgttggagc
acaagtcctgcagaccgaccgacattcgaagaactcgttaaaaagtttgaggaaatccgc
aaaacctatgactggcagttcagcaccaacttccccatgtctcagatatgctga
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