Alkalimarinus alittae: NKI27_09025
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Entry
NKI27_09025 CDS
T08567
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
alkm
Alkalimarinus alittae
Pathway
alkm00790
Folate biosynthesis
alkm01100
Metabolic pathways
alkm01240
Biosynthesis of cofactors
Module
alkm_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
alkm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NKI27_09025 (folC)
Enzymes [BR:
alkm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NKI27_09025 (folC)
6.3.2.17 tetrahydrofolate synthase
NKI27_09025 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
UZE97858
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Position
1994640..1995947
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AA seq
435 aa
AA seq
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MTKSYQDELQQWLTLIEQNHPSDIEMGLDRTLTVYTRLRKGRLAKQVVLVAGTNGKGSTI
AVLERLLLEAGLSVGVYSSPHIHIYNERIRINGELIDDKRLVESFQVVEKARRTTPLTYF
ECGTLGALYCLERARLDVVLLEVGLGGRLDAVNIVDPDLSIITSVDIDHVEWLGDNRESI
GFEKAGIFRQGVPAIYGGDNPPESVIQQANAQNIDLHIHDTHFGLRNQPSEAVADYSWVF
DTQPSQSAQRVVGYLRDQTGSTKEILMPYSLLPESNILTAIQAMACLGHLTNDTHILKAL
DGFAVKGRFEVYGSQPLVLLDVGHNPHAARFLSRRLSEIKGGRPVYAVFSVLTDKDVNGI
VEGLNGQIDHWYIAPLACPRAMKLPEICNALSNNQQQFTEYDGLNNAFNEAVNVAKESDG
IVMCFGSFHVVSDIN
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgactaagtcctatcaagacgagttacaacagtggttgactttaatagagcaaaatcat
ccttctgatattgaaatggggttagacagaactctcacagtttacactaggctcaggaag
gggcgacttgcaaagcaagtagtgctggtcgcaggtacaaatggtaaaggttccactatc
gcggtgcttgaacggttgttattagaggccggtctaagtgttggggtttatagttcaccc
catattcatatctataatgaacgtatcagaattaatggcgagcttatagatgataaacgt
cttgtagaaagctttcaggtcgtcgaaaaagcgcgccgcacaacacctttaacgtatttt
gaatgtggtactctcggtgcactttactgccttgagcgggcgcggctagatgtcgttttg
ctcgaggtaggcctaggtggacggcttgacgcggtaaatattgtcgatccagatctttct
attatcacatcggttgatattgaccatgttgagtggctaggcgacaaccgagaaagtatc
ggttttgaaaaggccggaatctttcgacagggtgtgcctgctatatatggcggcgataat
ccaccagaaagcgttattcaacaagctaacgctcaaaatatagatcttcatatacatgac
acccactttggcttaaggaatcagccgagcgaagcagttgcagactatagctgggtgttc
gatacccagccttctcaaagtgcacagagagtagtcggttatttgcgtgatcaaacgggc
tcaactaaagagattttaatgccctatagcttgttgccagaaagtaatatattaacggct
attcaagcaatggcgtgtcttggtcatcttactaatgacactcacattttaaaagcgtta
gatggttttgcggttaaggggcggtttgaggtttatggcagccaaccgctagtgctttta
gatgtaggtcataacccccatgctgccaggtttttatctcgtcgactgtcagagataaaa
ggggggaggcctgtttatgcggtgttttcagtacttacagataaagatgttaatggcatt
gttgaaggattgaacggccaaatagatcattggtatattgctccgctcgcatgtccgcgt
gcaatgaaattgccagaaatttgcaatgcgctcagcaacaatcaacagcagtttacagag
tatgatgggcttaacaatgcttttaatgaggcagttaacgttgcaaaagaaagtgacgga
attgtaatgtgctttggctcctttcatgttgtttctgatataaactga
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