Actinomadura madurae: LUW76_10760
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Entry
LUW76_10760 CDS
T08933
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00010
Glycolysis / Gluconeogenesis
amaz00020
Citrate cycle (TCA cycle)
amaz00620
Pyruvate metabolism
amaz00785
Lipoic acid metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01120
Microbial metabolism in diverse environments
amaz01200
Carbon metabolism
amaz01210
2-Oxocarboxylic acid metabolism
Module
amaz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LUW76_10760 (pdhA)
00020 Citrate cycle (TCA cycle)
LUW76_10760 (pdhA)
00620 Pyruvate metabolism
LUW76_10760 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LUW76_10760 (pdhA)
Enzymes [BR:
amaz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LUW76_10760 (pdhA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
URM94765
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Position
2306517..2307620
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AA seq
367 aa
AA seq
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MAETVQAAPARSRSARGTKAPRPKSAAASPKAPDAGTLVGYYRQMLLIRRFEERAARAYT
EAKIGGYCHLNLGEEATVVGLMAALRPTDYLFTNYREHGYALAKGIGAERVMAELYGRST
GVSKGWGGSMHLFDAEARLLGGYGIVGGQVPLAAGAALAVSYKGGDEVVMCHMGDGTTAI
GAFHESLNIAGLWDLPVVFVVINNGLGMGTTVENSSAEPELYRRGAAYRMESARVDGTDV
VAVRDAARAAVERARSQSKPYLLETVSPRLKGHSVVDPARYRSKEEKEALKAADPLARMA
LELEEAGILSHDDRDTLDAEVTAEVDAAAAFADDSPAPEVSTLFDYTYATPVPGELRRLP
ADPVFGS
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atggctgagaccgtccaggccgctccggcgcggagccggagcgcgcgcggcacgaaggct
ccccgcccgaagagcgccgcggcatcgccgaaggcgcccgacgccggcaccctcgtcggc
tactaccggcagatgctgctgatcaggcggttcgaggagcgggccgcccgcgcctacacc
gaggccaagatcggcggctactgccacctgaacctcggcgaggaggcgacggtcgtcggg
ctgatggccgcgctgcggcccaccgactacctgttcacgaactaccgcgagcatggttac
gcgctggccaaggggatcggcgccgagcgcgtcatggccgagctgtacgggcggtcgacc
ggcgtctccaagggctggggcgggtcgatgcacctgttcgacgccgaggcgcggctgctc
ggcgggtacgggatcgtcggcggccaggtgccgctcgcggccggcgccgcgctcgccgtg
tcctacaagggcggcgacgaggtcgtcatgtgccacatgggcgacgggacgaccgccatc
ggcgcgttccacgagtcgctgaacatcgccggcctctgggacctcccggtcgtcttcgtc
gtgatcaacaacggcctcggcatgggcaccaccgtggagaacagctccgccgagcccgag
ctgtaccggcgcggcgccgcgtaccggatggagagcgcccgggtggacggcaccgacgtc
gtcgcggtgcgggacgccgcgcgcgcggccgtcgagcgcgcccggtcgcagagcaagccg
tacctgctggagaccgtcagtccccggctgaagggccactcggtcgtcgacccggcccgc
taccggtccaaggaggagaaggaggcgctgaaggccgccgacccgctggcccggatggcg
ctggagctggaggaggccgggatcctctcccacgacgaccgcgacacgctggacgccgag
gtgacggccgaggtcgacgccgccgccgcgttcgccgacgacagcccggcccccgaggtc
tccacgctgttcgactacacctacgccaccccggtcccgggcgagctgcgccggctcccc
gccgaccccgtcttcggttcctga
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