Actinomadura madurae: LUW76_12610
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Entry
LUW76_12610 CDS
T08933
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00790
Folate biosynthesis
amaz01100
Metabolic pathways
amaz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LUW76_12610
Enzymes [BR:
amaz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LUW76_12610
6.3.2.17 tetrahydrofolate synthase
LUW76_12610
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
URN01577
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Position
complement(2702420..2703790)
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AA seq
456 aa
AA seq
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MGRGVEWEIDPSLDRIRDLVDVLGEPHRAYPVIHIAGTNGKSSTARLVEALLRERGLRTG
LYTSPEMTTLRERIAIDGEPVSEERFVETFNDVLPYLQLIDDKHPARLSFFEVLTAMAFA
AFADAPVDVAVVEAGMGGVWDATNVADGAVAVITPIGLDHTRYLGDTLEEIAGEKAGIIK
PGSVAVLAQQPVEAAEVLLRRVVETGAAVAREGVEYGVLGRDVAVGGQQLSLRGLHGVYD
EIFLPLFGEHQASNAATALAAVEAFASGAPTRGEPNLEAATRIAPGETYIGGDEGQLDPA
LVRSGFAKSASPGRLEVARTGPTVLLDSAHNPAGMAATVATVTESFGFTRLAGVLAISAD
KDVAGVLDQLEPVLAELVVTRNSSPRSMPPEELAELAESIFGPERVHVAERLDDAIDRAI
GLAEETGEYQGAGVLITGSVVTAGDARILLRVEEGR
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgggacgcggcgtcgagtgggagatcgacccgagcctcgaccggatccgcgatctggtg
gacgtcctgggagagccgcaccgcgcgtatccggtgatccacatcgccgggacgaacggc
aagtccagcaccgcccggctcgtcgaggcgctgctgcgcgagcgcgggctgcgcaccggg
ctctacaccagccccgagatgacgacgctgagggagcgcatcgcgatcgacggcgagccc
gtctccgaggagcggttcgtcgagacgttcaacgacgtcctgccctacctccagctgatc
gacgacaagcacccggcgcggctgtcgttcttcgaggtcctcacggcgatggcgttcgcg
gcgttcgcggacgcgccggtcgacgtcgcggtggtcgaggccggcatgggcggggtgtgg
gacgcgaccaacgtcgcggacggcgcggtcgcggtgatcaccccgatcgggctggaccac
acccgctacctgggcgacacgctggaggagatcgccggggagaaggcgggcatcatcaag
ccgggatcggtcgcggtgctggcgcagcagccggtcgaggcggccgaggtgctgctgcgg
cgggtcgtggagaccggcgccgcggtggcgcgcgagggcgtggagtacggcgtgctcggc
cgggacgtcgcggtcggcggccagcagctcagcctgcggggcctgcacggcgtctacgac
gagatcttcctgccgctgttcggcgagcaccaggcgagcaacgcggccacggcgctcgcc
gccgtggaggcgttcgcgagcggcgcgccgacgcggggggagcccaacctggaggccgcg
acccggatcgcgcccggggagacctacatcggcggcgacgagggccagctggacccggcg
ctggtgcgcagcggcttcgccaagtcggcctcgccgggacggctggaggtcgcgcggacg
ggcccgaccgtcctgctggactcggcgcacaacccggccgggatggcggcgaccgtcgcc
acggtcaccgagtcgttcggcttcacccggctcgccggggtgctcgcgatcagcgccgac
aaggacgtcgcgggcgtcctcgaccagctcgaacccgtcctggccgagctggtggtcacc
cgcaactcctcgccgcgctcgatgccgcccgaggagctggccgagctcgccgagagcatc
ttcggccccgagcgcgtccatgtcgccgagcgcctggacgacgcgatcgaccgggcgatc
gggctcgccgaggagaccggcgagtaccagggcgccggcgtgctgatcaccggctcggtg
gtcacggcgggcgacgcccggatcctgctgcgcgtcgaggaaggccggtga
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