Actinomadura madurae: LUW76_37955
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Entry
LUW76_37955 CDS
T08933
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00020
Citrate cycle (TCA cycle)
amaz00630
Glyoxylate and dicarboxylate metabolism
amaz00785
Lipoic acid metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01120
Microbial metabolism in diverse environments
amaz01200
Carbon metabolism
amaz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LUW76_37955
00630 Glyoxylate and dicarboxylate metabolism
LUW76_37955
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LUW76_37955
Enzymes [BR:
amaz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
LUW76_37955
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
LUW76_37955
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
LUW76_37955
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
LUW76_37955
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
URM99642
LinkDB
All DBs
Position
complement(7983321..7987046)
Genome browser
AA seq
1241 aa
AA seq
DB search
MSTESSQTSADPKTTDFGANEWLVDELYQKYLEDPNNVDEAWWNFFADYQPDSRPTSATP
ASPQAPADSAAPQAGNGTAAAPPTPQRPVTPPKATDGTAPAAKAPAPKADRPAPPPVPAG
AEEVRLRGVAARTATNMEASLGVPTATSVRAVPAKLLIDNRIVINNHLKRGRGGKVSFTH
LIGYAIVKALTSMPEMNAAFTEVDGKPVLVRPEHVNFGLAIDLQKSDGSRQLVVPSVKAA
ETLDFRQFWAAYEEIVRKARGGKLTLEDFQGTTISLTNPGTIGTVHSVPRLMPGQGTIIG
VGAMEYPAEFAGASGETLSRMGISKVMTLTSTYDHRIIQGAQSGDFLRRIHQLLLGEDGF
YDEIFEALRIPYEPVRWVKDISATHEDDVAKVARVHELIHAYRVRGHLMADTDPLEYKQR
RHPDLDILKHGLTLWDLEREFATGGFGGKPTMKLREILGVLRMAYCRTVGIEYMHIQDPE
ERAWIQERVEVPHDKPSREEQLHVLRRLNSAEAFETFLQTKFVGQKRFSLEGGESVIPLL
DSVISAAAKDSLDEVVIGMAHRGRLNVLANIVGKSYGQIFGEFEGNLDPRSAQGSGDVKY
HLGASGDFVASDGSKIHTELVANPSHLETVDPVLEGVVRAKQDLLDVGEAGFSVLPVLIH
GDAAFAGQGVVAETLNLSQLRGYRTGGTVHVIINNQVGFTTAPEYSRSSVYSTDVARMIQ
APIFHVNGDDPEACARVARLAFEYRQTFKKDVVIDMVCYRRRGHNEGENPSFTQPLMYDL
IDAKRSVRKLYTEALIGRGDITVEEAEQALRDYQEQLERAFTETREAVKKPLEPGSVVKP
DVEERIPIDHGKAGSAIPQETVKRLIESQVALPEGFTPHPRLQPILQRRAQMIEDDAIDW
ATGELLAMGSLLIDGHPVRLVGQDTRRGTFGQRHAVLVDRKTGEEYTPLKQFGQGVSKFY
VHDSLLSEYAAMGFEYGYSMTRPDALVCWEAQFGDFANGAQSVVDEYISSGEQKWGQHSG
VVLLLPHGYEGQGPDHSSARIERYLQLCAQDNMTVVYPTTPANYFHLLRWQVLSGRHKPL
VVFTPKSLLRLKAATSPVAQITGGAFQPVIPESDPAIDPAGVRRVLLTTGKIYYDVVKAR
DAAGANDTAVVRIERLYPPPVDEIKAELAKYPADAEVVFVQDEPANMGAWPFMALKLPHH
IEGLRMSRVSRPASSSPAVGSAKLHQAEQEALLARLFGEQK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacagagtcgtcgcaaacaagtgccgacccgaagaccacagatttcggcgccaac
gaatggctggtcgacgagctgtaccagaagtacctcgaagacccgaacaacgttgacgaa
gcctggtggaacttcttcgctgactaccagccggacagccggcccacgtccgcgaccccc
gcgtccccccaggcgcccgccgacagcgcggccccgcaggccggcaacggcaccgcggcc
gcaccgccgacaccgcagcggccggtgacgccgccgaaggcgaccgacggcacggccccg
gccgccaaggcccccgcgccgaaggccgacaggccggccccgccgccggtccccgcgggc
gccgaggaggtccggctgcgcggcgtcgccgcccggacggccaccaacatggaggccagc
ctcggcgtgccgacggcgacgagcgtgcgggccgtcccggcgaagctgctgatcgacaac
cgcatcgtcatcaacaaccacctcaagcgcggccgcggcggcaaggtctcgttcacgcac
ctgatcggttacgcgatcgtcaaggcgctcacctcgatgccggagatgaacgccgcgttc
accgaggtggacggcaagccggtgctggtccgccccgagcacgtgaacttcggcctggcg
atcgacctgcagaagagcgacggctcgcggcagctcgtggtgccgagcgtcaaggccgcc
gagacgctggacttccgccagttctgggccgcctacgaggagatcgtccgcaaggcccgc
ggcggcaagctcaccctggaggacttccagggcaccacgatcagcctcaccaacccgggc
acgatcggcacggtccactcggtgccgcggctgatgcccggccagggcacgatcatcggc
gtgggcgccatggagtacccggccgagttcgcgggcgcgtccggcgagaccctgtcgcgc
atggggatcagcaaggtcatgacgctgacctccacctacgaccaccggatcatccagggc
gcgcagtccggcgacttcctgcgccgcatccaccagctgctcctcggcgaggacggcttc
tacgacgagatcttcgaggcgctgcgcatcccgtacgagccggtgcgctgggtcaaggac
atctccgccacgcacgaggacgacgtcgccaaggtcgcccgcgtgcacgagctgatccac
gcctaccgggtccgcggccacctgatggccgacaccgacccgctggagtacaagcagcgc
cgccaccccgacctcgacatcctcaagcacggcctcaccctgtgggacctggagcgcgag
ttcgcgaccggcgggttcggcggcaagccgacgatgaagctgcgcgagatcctcggcgtg
ctgcggatggcgtactgccggacggtcggcatcgagtacatgcacatccaggacccggag
gagcgcgcctggatccaggagcgcgtggaggtcccgcacgacaagccgtcgcgcgaggag
cagctgcacgtgctccgccgcctgaacagcgccgaggcgttcgagacgttcctgcagacc
aagttcgtcgggcagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctg
gactcggtgatctcggcggcggcgaaggacagcctcgacgaggtcgtcatcggcatggcg
caccgcggccggctgaacgtcctcgccaacatcgtcggcaagtcctacgggcagatcttc
ggcgagttcgagggcaacctcgacccgcgcagcgcgcagggctccggcgacgtgaagtac
cacctcggcgcgtccggcgacttcgtcgcgagcgacggctccaagatccacaccgagctg
gtcgcgaacccgtcccacctggagacggtcgacccggtgctggagggcgtcgtccgcgcc
aagcaggacctgctggacgtcggcgaggccgggttcagcgtgctgccggtgctcatccac
ggcgacgccgcgttcgccgggcagggcgtggtggccgagacgctgaacctgtcgcagctg
cgcggctaccgcaccggcggcaccgtgcacgtgatcatcaacaaccaggtgggcttcacc
accgcccccgagtactcgcggtccagcgtgtactccacggacgtggcccggatgatccag
gcgccgatcttccacgtcaacggcgacgacccggaggcgtgcgcgcgggtggcgcggctg
gcgttcgagtaccggcagacgttcaagaaggacgtcgtcatcgacatggtctgctaccgg
cggcgcggccacaacgagggcgagaacccctcgttcacgcagccgctcatgtacgacctg
atcgacgcgaagcggtcggtgcgcaagctgtacaccgaggcgctgatcggccgcggcgac
atcacggtcgaggaggccgagcaggcgctgcgcgactaccaggagcagctggagcgggcc
ttcaccgagacccgcgaggccgtgaagaagcccctggagccgggctcggtcgtgaagccg
gacgtcgaggagcgcatcccgatcgaccacggcaaggccgggtcggcgatcccgcaggag
accgtcaagcggctcatcgagtcgcaggtcgccctgccggaggggttcaccccgcacccg
cggctccagccgatcctgcagcgccgcgcccagatgatcgaggacgacgcgatcgactgg
gcgaccggcgagctgctggcgatgggctcgctgctgatcgacggccacccggtgcggctc
gtcgggcaggacacccggcgcggcacgttcggccagcggcacgcggtcctcgtcgaccgc
aagacgggcgaggagtacacgccgctcaagcagttcgggcagggcgtgtcgaagttctac
gtgcacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgatg
acccgcccggacgcgctggtctgctgggaggcccagttcggcgacttcgccaacggcgcc
cagtcggtggtggacgagtacatctcctccggcgagcagaagtggggccagcactccggc
gtcgtgctgctgctgccgcacggctacgagggccaggggcccgaccactcgtccgcgcgg
atcgagcggtacctgcagctgtgcgcgcaggacaacatgacggtcgtgtacccgaccacc
ccggcgaactacttccacctgctgcgctggcaggtgctgtcggggcgccacaagccgctg
gtggtgttcacgccgaagtcgctgctgcggctgaaggcggcgacgtccccggtcgcgcag
atcaccggcggcgcgttccagccggtcatcccggagagcgacccggcgatcgacccggcg
ggcgtgcggcgggtgctgctcaccaccggcaagatctactacgacgtggtgaaggctcgg
gacgccgcgggcgcgaacgacaccgcggtggtccggatcgagcggctgtacccgccgccc
gtggacgagatcaaggcggagctggccaagtacccggcggacgccgaggtcgtcttcgtg
caggacgagccggccaacatgggcgcctggccgttcatggcgctgaagctgccgcaccac
atcgaggggctgcggatgtcgcgggtctcgcgcccggcgtcctcgtccccggcggtgggc
tcggcgaagctgcaccaggcggagcaggaggcattgctggcccggctgttcggcgaacag
aaatag
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