Amycolatopsis mediterranei U32: AMED_2113
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Entry
AMED_2113 CDS
T01269
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00010
Glycolysis / Gluconeogenesis
amd00020
Citrate cycle (TCA cycle)
amd00620
Pyruvate metabolism
amd00785
Lipoic acid metabolism
amd01100
Metabolic pathways
amd01110
Biosynthesis of secondary metabolites
amd01120
Microbial metabolism in diverse environments
amd01200
Carbon metabolism
amd01210
2-Oxocarboxylic acid metabolism
Module
amd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AMED_2113 (aceE)
00020 Citrate cycle (TCA cycle)
AMED_2113 (aceE)
00620 Pyruvate metabolism
AMED_2113 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AMED_2113 (aceE)
Enzymes [BR:
amd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AMED_2113 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADJ43919
UniProt:
A0A0H3D156
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All DBs
Position
complement(2256865..2259660)
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AA seq
931 aa
AA seq
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MAPQNDGASGKETPARVRVIRDGLAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLML
RILERARERNVGVPALTSTDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQR
PGVGVGGHISTYASSAALYEVGFNHFFRGKDHSGGGDQIYIQGHASPGIYARAFLEGRLS
ESQLDGFRQEFSHAGEGGGLPSYPHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDR
GIKNTDDQHIWAFLGDGEMDEAESRGLIHVAAGEGLDNLTFVINCNLQRLDGPVRGNGKI
IQELESYFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNVTPDGDYQTYKANDGAFVR
EHFFGRDPRTKDLVKDLSDADIWNLKRGGHDYRKVYAAYKSALEHHGQPTVILAHTIKGY
GLGPAFEGRNATHQMKKLTLDDLKLFRDSQRIPISDEELERNPKLPPYYHPGANSPEIEY
MIGRRKALGGFLPERRPKAAKALVLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDS
EIGKRVVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDASLMLAYKESEKGQLLHEGI
NEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAG
RTTLTGEGLQHADGHSLLLAATNPAAVAYDPAWSFEIAHIVKDGLRRMYGEAGPDGNGEN
VFYYMTIYNEPYQQPAEPENLDVDGLLKGLYKYADAPGGDGPEVQILVSGVTMPDALKAQ
KMLAEEWGVRAAVWSVTSWTELRREAVEIDHDNLLYPGSEPRVPYVTEALSGSNGPVVAV
SDWMRAVPDLIRPYVPTDMLTLGTDGFGFSDTRPAARRKFLVDAESITVGALSILAKRGE
VEQAKVLEAATKYRLDDIAAAGPQTSESGNA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaacgacggcgcctccggcaaggagaccccggcacgcgtacgcgtcatc
cgtgacggactggcggcgcacctgcccgacatcgacccggaggagaccgccgagtggctg
gactccttcgacgaggctctggcgaggggcggtcagcagcgggcccggtacctgatgctg
cgcatcctcgagcgggcccgggaacggaacgtcggcgtaccggccctgacctcgacggac
tacgtcaacaccatccccaccgagaacgagccgtggttccccggcgacgaggagatcgag
cgccgctaccgcgcctacatccggtggaacgcggcgatcatggtgcaccgcgcgcagcgc
ccgggcgtcggcgtcggcggccacatctcgacctacgcctcctcggccgcgctgtacgag
gtgggcttcaaccacttcttccgcggcaaggaccactccggcggcggcgaccagatctac
atccagggccacgcctcccccggcatctacgcccgcgcgttcctcgaaggccggctgagc
gagtcgcagctcgacggcttccgccaggagttctcgcacgccggcgagggcggcggcctg
ccgtcgtacccgcacccgcggctgatgccggagttctgggagaacccgacggtgtcgatg
ggcctcggcccgatgaacgccatctaccaggcccggttcaaccggtacctgcgcgaccgc
ggcatcaagaacaccgacgaccagcacatctgggcgttcctcggcgacggcgagatggac
gaggccgaatcccgcggcctgatccacgtcgcggccggtgagggcctcgacaacctgacc
ttcgtgatcaactgcaacctgcagcggctcgacggcccggtgcgcggcaacggcaagatc
atccaggagctggagtcgtacttccgcggcgccggctggaacgtcatcaaggtgatctgg
ggccgcgagtgggactcgctgctgcacgccgaccgcgacggcgccctggtcaacctgatg
aacgtcaccccggacggtgactaccagacgtacaaggccaacgacggcgccttcgtccgc
gaacacttcttcggccgcgacccgcggacgaaggacctggtcaaggacctctccgacgcc
gacatctggaacctcaagcgcggcggccacgactaccgcaaggtgtacgcggcctacaag
tcggcgctggagcaccacggccagccgacggtgatcctggcccacaccatcaagggctac
ggcctgggcccggcgttcgagggccgcaacgccacgcaccagatgaagaagctcaccctc
gacgacctgaagctgttccgcgactcgcagcggatcccgatcagcgacgaggagctggag
cgcaacccgaagctgccgccgtactaccacccgggcgcgaactcgcccgagatcgagtac
atgatcggccgccgcaaggcgctcggcgggtttctgccggaacgccgtccgaaggccgcg
aaggcgctggtcctgccgggcgacaaggtctacgagggcatccggaagggctccggcaag
caggaggtcgccaccacgatggcgttcgtccggctggtccgcgagctggccaaggactcc
gagatcggcaagcgcgtcgtcccgatcatcccggacgaggcccgcaccttcggcctcgac
tcgatgttcccgacggccaagatctacaacccgcacggccagacctacacgtcggtcgac
gcgagcctgatgctggcctacaaggagtccgagaagggccagctgctgcacgagggcatc
aacgaggcgggctccaccgcgtcgttcaccgccgtcggcacgtcgtacgcgacgcacggc
gagccgatgatcccgatctacatcttctactcgatgttcgggttccagcggaccggtgac
ggcctgtacgccgccgccgaccagatggcccgcgggttcgtcctcggcgccaccgccggc
cgaaccaccctgacgggtgaaggcctgcagcacgccgacggccactcgctcctgctcgcg
gcgaccaacccggccgcggtggcctacgacccggcgtggtcgttcgagatcgcgcacatc
gtcaaggacggcctgcgccggatgtacggcgaggccggcccggacggcaacggcgagaac
gtcttctactacatgacgatctacaacgagccgtaccagcagcccgccgagccggagaac
ctcgacgtcgacggcctgctgaagggtctgtacaagtacgcggacgcgcccgggggcgac
ggtccggaggtgcagatcctggtctcgggcgtcacgatgccggacgcgctgaaggcgcag
aagatgctggccgaggagtggggcgtgcgggccgcggtgtggtcggtgacgtcgtggacc
gagctgcggcgcgaagccgtcgagatcgaccacgacaacctgctctacccgggcagcgag
ccgcgcgtgccgtacgtgacggaggcgctttcggggagcaacggcccggtcgtggcggtg
tcggactggatgcgcgcggtgccggacctgatccgcccatacgtcccgaccgacatgctg
acgctgggcacggacggcttcggcttctccgacacccggccggcggcgcggcggaagttc
ctggtcgacgccgagtcgatcaccgtcggggcgctgtcgatcctggccaagcgcggcgag
gtcgagcaggcgaaggtcctcgaagcggccacgaagtaccggctcgacgacatcgcggcc
gccgggccgcagacgtcggagtccggcaacgcgtga
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