KEGG   Ailuropoda melanoleuca (giant panda): 100467699
Entry
100467699         CDS       T01329                                 
Symbol
TPH1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00380  Tryptophan metabolism
aml00790  Folate biosynthesis
aml01100  Metabolic pathways
aml04726  Serotonergic synapse
Module
aml_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    100467699 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100467699 (TPH1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    100467699 (TPH1)
Enzymes [BR:aml01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     100467699 (TPH1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT ACT_4 zf-C2HE DUF5370 DUF262
Other DBs
NCBI-GeneID: 100467699
NCBI-ProteinID: XP_019665027
Ensembl: ENSAMEG00000018200
LinkDB
Position
16:complement(50984661..51012053)
AA seq 444 aa
MIEDNKENKDHSLERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTVKEDGMETVPWFPKKISDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHSLSGHAKVKPFDPKVTC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA
MNELQHDLDVVSDALAKVSREPSI
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgattgaagacaataaggaaaataaagaccattccttagaaagaggaagagcaactctc
attttttccttgaagaatgaagttggtggacttataaaagcactaaaaatcttccaggag
aagcatgtgaacctgttacatatcgagtcccgaaaatcaaagagaagaaactcagaattt
gagatttttgttgactgtgatatcaacagagaacaattgaatgatatttttcatctgttg
aagtcccatactaatgttctctctgtgaatccaccagataattttactgtgaaggaagat
ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccattgtgccaac
agagttctgatgtatggatctgaactggatgcagatcatcctggcttcaaagacaatgtc
taccgtaaaagacggaagtattttgcagacttggctatgaactataaacatggagacccc
attcccaaggttgaattcactgaagaggagattaagacctggggaactgtgtttcaagag
ctcaacaaactttacccaacccatgcctgcagagagtacctcaaaaacttacctttgctt
tctaaatattgtggctatcgggaagataatatcccacaattggaagatgtctcaaacttt
ttaaaggagcgcacgggtttttccatccgtcccgtggccggttacttatcaccaagagat
ttcttatcaggtttagccttccgggttttccactgcacacagtacgtgagacacagttcc
gaccctctctataccccagagccagatacttgccatgaactcttaggtcatgtccccctt
ttggcggaacctagttttgctcaattctcccaagaaattggcctggcttcccttggagct
tcagaggaggctgttcaaaaactggcaacgtgctactttttcaccgtggagtttggtctc
tgtaaacaagatgggcagttgcgagtctttggggccggattactttcttctatcagtgaa
cttaagcattcactttctggacatgccaaagtaaagccctttgatcccaaggttacctgc
aagcaggagtgtctcatcacaacttttcaggatgtctactttgtatctgaaagctttgaa
gatgcaaaggaaaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag
tataatccatacacacggagtattcagatcttgaaagacaccaagagcataaccagcgcc
atgaacgagctgcagcatgatctcgatgttgtcagtgatgcccttgcgaaggtcagcaga
gagccaagcatctga

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