KEGG   Ailuropoda melanoleuca (giant panda): 100475452
Entry
100475452         CDS       T01329                                 
Symbol
HSD17B8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8 isoform X2
  KO
K13370  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00061  Fatty acid biosynthesis
aml00140  Steroid hormone biosynthesis
aml01100  Metabolic pathways
aml01212  Fatty acid metabolism
Module
aml_M00873  Fatty acid biosynthesis in mitochondria, animals
aml_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    100475452 (HSD17B8)
   00140 Steroid hormone biosynthesis
    100475452 (HSD17B8)
Enzymes [BR:aml01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     100475452 (HSD17B8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     100475452 (HSD17B8)
SSDB
Motif
Pfam: adh_short_C2 adh_short KR Epimerase RmlD_sub_bind RNA_pol_Rpb1_4
Other DBs
NCBI-GeneID: 100475452
NCBI-ProteinID: XP_002914381
Ensembl: ENSAMEG00000001698
UniProt: G1L4G6
LinkDB
Position
5:28415817..28418035
AA seq 259 aa
MASQLRLRSALALVTGAGSGIGRAVSVRLAREGATVAACDLDRAAACETVCLLGGQGSEE
AAPGGAHAAFQADVSEAGAVRCLLEQVQAWFSRPPSVVVSCAGITRDEFLLRMSEDDWDR
VIAVNLKGIFLVTQAAAQALVSSGCHGSIINISSITGKVGNMGQTNYAASKAGVIGLTQT
AARELGRHGIRCNSVLPGFITTPMTQKVPQQVLDKVIGMIPMGHMGDPEDVADVVAFLAS
EDSGYITGASVEVTGGLFM
NT seq 780 nt   +upstreamnt  +downstreamnt
atggcgtctcagctcaggctccgctccgcgctggccctggtcacaggcgcgggtagcggc
atcggccgggccgtcagtgtgcgcctggccagagagggggccaccgtggccgcttgcgac
ttggatagggcggcggcatgcgagacggtgtgcctgctgggcgggcaggggagcgaggag
gcggcgcccggcggggcccacgccgccttccaggctgacgtgtctgaagccggggcggtc
aggtgcctgctggaacaagtacaggcctggttttctcgcccgccatctgtcgttgtgtcc
tgtgcggggatcaccagggatgagtttctgctccgcatgtctgaggatgactgggacaga
gtcatagctgtcaatctcaagggcatctttctagtcactcaggctgcagcccaagccctg
gtgtccagtggttgccatgggtccatcatcaacatcagtagcatcacagggaaggtgggg
aacatgggacagacaaactacgcagcatccaaggctggagtgattgggctgacccagact
gcagctcgggagcttggacgacatgggatccgctgtaactctgtcctcccggggttcatt
acaacacccatgacacagaaagtgccacagcaagtgctggacaaggtgattggaatgatc
ccgatgggacatatgggggatcctgaggatgtggcagatgtggttgcattcttggcatct
gaagacagtggatacatcacaggggcctcagtggaagtcactggaggtcttttcatgtaa

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