Ailuropoda melanoleuca (giant panda): 100475452
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Entry
100475452 CDS
T01329
Symbol
HSD17B8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8 isoform X2
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00061
Fatty acid biosynthesis
aml00140
Steroid hormone biosynthesis
aml01100
Metabolic pathways
aml01212
Fatty acid metabolism
Module
aml_M00873
Fatty acid biosynthesis in mitochondria, animals
aml_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100475452 (HSD17B8)
00140 Steroid hormone biosynthesis
100475452 (HSD17B8)
Enzymes [BR:
aml01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100475452 (HSD17B8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100475452 (HSD17B8)
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Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
RmlD_sub_bind
RNA_pol_Rpb1_4
Motif
Other DBs
NCBI-GeneID:
100475452
NCBI-ProteinID:
XP_002914381
Ensembl:
ENSAMEG00000001698
UniProt:
G1L4G6
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Position
5:28415817..28418035
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AA seq
259 aa
AA seq
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MASQLRLRSALALVTGAGSGIGRAVSVRLAREGATVAACDLDRAAACETVCLLGGQGSEE
AAPGGAHAAFQADVSEAGAVRCLLEQVQAWFSRPPSVVVSCAGITRDEFLLRMSEDDWDR
VIAVNLKGIFLVTQAAAQALVSSGCHGSIINISSITGKVGNMGQTNYAASKAGVIGLTQT
AARELGRHGIRCNSVLPGFITTPMTQKVPQQVLDKVIGMIPMGHMGDPEDVADVVAFLAS
EDSGYITGASVEVTGGLFM
NT seq
780 nt
NT seq
+upstream
nt +downstream
nt
atggcgtctcagctcaggctccgctccgcgctggccctggtcacaggcgcgggtagcggc
atcggccgggccgtcagtgtgcgcctggccagagagggggccaccgtggccgcttgcgac
ttggatagggcggcggcatgcgagacggtgtgcctgctgggcgggcaggggagcgaggag
gcggcgcccggcggggcccacgccgccttccaggctgacgtgtctgaagccggggcggtc
aggtgcctgctggaacaagtacaggcctggttttctcgcccgccatctgtcgttgtgtcc
tgtgcggggatcaccagggatgagtttctgctccgcatgtctgaggatgactgggacaga
gtcatagctgtcaatctcaagggcatctttctagtcactcaggctgcagcccaagccctg
gtgtccagtggttgccatgggtccatcatcaacatcagtagcatcacagggaaggtgggg
aacatgggacagacaaactacgcagcatccaaggctggagtgattgggctgacccagact
gcagctcgggagcttggacgacatgggatccgctgtaactctgtcctcccggggttcatt
acaacacccatgacacagaaagtgccacagcaagtgctggacaaggtgattggaatgatc
ccgatgggacatatgggggatcctgaggatgtggcagatgtggttgcattcttggcatct
gaagacagtggatacatcacaggggcctcagtggaagtcactggaggtcttttcatgtaa
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