Amycolatopsis methanolica: AMETH_2324
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Entry
AMETH_2324 CDS
T03230
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase complex, dehydrogenase (E1) component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00010
Glycolysis / Gluconeogenesis
amq00020
Citrate cycle (TCA cycle)
amq00620
Pyruvate metabolism
amq00785
Lipoic acid metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01120
Microbial metabolism in diverse environments
amq01200
Carbon metabolism
amq01210
2-Oxocarboxylic acid metabolism
Module
amq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AMETH_2324 (aceE)
00020 Citrate cycle (TCA cycle)
AMETH_2324 (aceE)
00620 Pyruvate metabolism
AMETH_2324 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AMETH_2324 (aceE)
Enzymes [BR:
amq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AMETH_2324 (aceE)
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GFIT
Motif
Pfam:
Transketolase_N
PDH_E1_M
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AIJ22416
UniProt:
A0A076MU38
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Position
complement(2414691..2416994)
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AA seq
767 aa
AA seq
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MSEPAVSPPATDVLRAVEDRVLWLSSAIINHANRVRPNPSGLKVGGHQASSASMVSIMTA
LWFNHLRPADRVSVKPHASPVLHAINHLLGELDASYLPRLREFGGLQSYPSRTKDPDPAD
YSTGSVGIGATAPIWGAISRRYVDTKFGGAGTGRQYSLVGDAELDEGAVWEAVLDPGVAE
LGEIVWIVDLNRQSLDRVVPNIAADKLQGMFAAAGWQVIVLKYGRLLEELFTRPGGAQLR
QRIDAMTNPEYQRLLRCDAAELRRRLPGDSPAIGALLDDLDDTTLTDAIANLGGHDLAAL
DQAFAAIDDTRPTVVFAYTVKGHGLATKGHPQNHSALLTDAQMRELAERLGADLDDPWRA
FADGSPEQELCRATAKRLRRREIPATTPPPVPSDFGRTPTGTATTQAALGRALLDLTREA
PDTARRVVTVSPDVSSTTNLGGWVNKVGVWSVQERPDWFADDSETILHWRERPTGQHIEL
GIAETNLVGLLGELGATWSRWGQPLLPIGVLYDPFVERALEPWSYGIYAGGQSILIGTPS
GVTLAPEGGAHQSIKTPSIGLEQPGCLTYEPAFAIDAEWTLLAAMAQLGKPGGSSAYLRL
STRPVDQTLADVPADPAARERRRRQVVAGAYPLRRPDGAAVTIAVMGALVPEALDAAARL
DQIGVPADVVCVTSPDLLHRAVRARQGHERADTWILDAAFPADRAAPLVTVLDGHPHTLA
FLATINRVRTTALGVTGFGQSGSLEDVYRHHGLDSDSIVRAALDVTG
NT seq
2304 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagcccgccgtctccccgcccgccaccgacgtgctgcgcgcggtcgaggaccgg
gtgctgtggctgtccagcgcgatcatcaaccacgccaaccgcgtgcggccgaacccgtcg
gggctcaaggtcggcggccaccaggcgtcctcggcgtcgatggtctcgatcatgaccgcg
ctgtggttcaaccacctccgcccggcggaccgcgtctcggtcaagccgcacgcctcgccc
gtgctgcacgcgatcaaccacctgctcggcgagctggacgcgtcctacctgccgcggctg
cgcgagttcggcgggctgcagagctaccccagccgcaccaaggatcccgacccggccgac
tactcgaccggctcggtcggcatcggcgccaccgcaccgatctggggcgcgatctcccgg
cgctatgtcgacaccaagttcggcggcgcgggcaccggccgccagtactcgctggtcggc
gacgccgaactggacgagggcgcggtgtgggaggccgtcctcgaccccggcgtggccgag
ctcggcgagatcgtctggatcgtcgacctcaaccgccagtccctggaccgcgtcgtgccg
aacatcgccgccgacaagctgcagggcatgttcgcggccgcgggctggcaggtcatcgtc
ctcaagtacggccgcctgctggaagaactgttcacccgccccggcggcgcgcaactgcgg
cagcgcatcgacgccatgaccaacccggaataccagcggctgctgcgctgcgacgccgcc
gaactgcgccgccgcctccccggtgacagccccgccatcggggccctgctcgacgacctc
gacgacaccaccctcaccgacgcgatcgccaacctcggcggccacgacctcgccgcactc
gaccaggccttcgcggcgatcgacgacacccgcccgacggtcgtcttcgcctacacggtc
aagggccacggcctggccaccaagggccacccgcagaaccactccgccctgctcaccgac
gcccagatgagggaactcgccgagcggctgggcgccgacctcgacgacccctggcgcgcc
ttcgccgacggcagccccgaacaggagctgtgccgggcgaccgcgaaacgcctgcgccgc
cgggaaatcccggcgaccactcccccgccggtgccgtcggatttcggccgcaccccgacc
ggcaccgccaccacccaggccgcgctgggccgcgccctgctcgacctcacccgcgaagcg
ccggacaccgcccgccgcgtcgtcacggtcagccccgacgtcagctccaccaccaacctg
ggcggctgggtcaacaaggtcggcgtctggtccgtgcaggaacggccggactggttcgcc
gacgacagcgaaaccatcttgcactggcgggaacgcccgaccggtcagcacatcgaactg
ggcatcgccgagaccaacctcgtcggcctgctcggcgaactcggcgccacctggagccgc
tggggccagccgctgctgcccatcggcgtgctctacgaccccttcgtggagcgcgcgctc
gaaccgtggtcctatggcatctacgccggcggccagtccatcctcatcggcaccccgtcc
ggcgtgaccctggcgcccgaggggggtgcgcaccagtccatcaaaaccccgtcgatcgga
ctggaacagcccggctgcctcacctacgaacccgcgttcgcgatcgacgccgagtggacg
ctgctcgcggcgatggcccagctcggcaagccgggcggcagctcggcctacctgcggctg
tccacccgcccggtcgaccagaccctcgccgacgtgcccgcggacccggccgcccgcgaa
cgccgccgccgccaggtcgtcgccggcgcgtatccgctgcgccgcccggacggcgcggcc
gtcaccatcgccgtgatgggcgcgctcgtccccgaagccctcgacgccgcggcccggctg
gaccagatcggcgtgcccgccgacgtcgtgtgtgtgaccagccccgacctgctccaccgc
gcggtccgcgcccggcagggccacgaacgggccgacacctggatcctggacgccgccttc
cccgccgaccgcgccgctcccctggtgaccgtcctcgacgggcacccgcacacgctggcg
ttcctcgccacgatcaaccgcgtccggacgacggcgctcggcgtgacgggcttcggccag
tccggctcgctcgaagacgtctaccggcaccacggcctggacagcgacagcatcgtccgc
gccgcgctcgacgtcaccggctga
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