Amycolatopsis sp. AA4: CU254_38615
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Entry
CU254_38615 CDS
T05278
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00280
Valine, leucine and isoleucine degradation
amyc00640
Propanoate metabolism
amyc00785
Lipoic acid metabolism
amyc01100
Metabolic pathways
amyc01110
Biosynthesis of secondary metabolites
amyc01210
2-Oxocarboxylic acid metabolism
Module
amyc_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CU254_38615 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CU254_38615 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CU254_38615 (pdhA)
Enzymes [BR:
amyc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CU254_38615 (pdhA)
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Motif
Pfam:
E1_dh
Motif
Other DBs
NCBI-ProteinID:
ATY15645
UniProt:
A0A2K8MCN3
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Position
8322914..8324119
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AA seq
401 aa
AA seq
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MPSEQWTHPEPGDGPAAVAAQPSPEQVIAGLRATSEGGAELTQLLTPEGQRVPSERFDRY
VEDVDDETLKNLYRDMVLVRRADREANAMQRQGQLGIWVPLLGQEAAQVGSGRALQPRDM
AFPSYREHGVAYTRGVDMRELIGIFRCTDHSGWDYQAHRFHPYTIVIGNQVLNAAGYAMG
QKFEGKVGDEGGEATICYFGDGATSQGDVHEGFVWAAVYDAPLVFFCQNNQWAISEPTER
QSRLPLYQRARGYGFPGIRVDGNDVLACLAVTRWALDECRHGNGPVLIEAFTYRMDAHTT
TDDPTRYRLSDELEEWKLKDPIERVRAFLARNGHADQAFFDSVQAEADQFAAELRDYTFN
MPEPPPDRVFSQVYAEPSPVLEAQREEYLSYLDGFAAAGEH
NT seq
1206 nt
NT seq
+upstream
nt +downstream
nt
atgccgtccgaacagtggacgcacccggaacctggagacgggccggccgccgtagcggcc
cagccttcccccgaacaggtgatcgccggtttgcgagcgacaagcgaaggtggcgctgag
ctgactcagctgctcacccccgagggccagcgcgtcccgtccgagcggttcgaccgctac
gtcgaggacgtcgacgacgaaacgctgaagaacctctaccgcgacatggtgctggtgcgc
cgcgcggaccgcgaggccaacgcgatgcagcgccaggggcagctgggcatctgggtgccg
ctgctcggccaggaagccgcgcaagtcgggtccgggcgcgcgctgcagccgcgggacatg
gcgttcccgagctaccgcgagcacggcgtcgcgtacacgcgcggcgtcgacatgcgcgag
ctgatcgggattttccggtgcaccgaccacagcggctgggactaccaggcccaccggttc
cacccgtacaccatcgtgatcggcaaccaggtgctcaacgccgctggttacgcgatgggc
cagaagttcgaaggcaaagtcggggacgagggcggcgaagccaccatctgctacttcggt
gacggcgcgacttcgcagggcgacgtgcacgaaggtttcgtctgggccgcggtgtacgac
gcgccgctggtcttcttctgccagaacaaccagtgggcgatatccgagccgaccgaacgc
cagtcgcggctgccgctctaccagcgcgcccgcggttacggcttccccggcatccgcgtg
gacggcaacgacgtcctcgcctgcctcgccgtcacccggtgggcgctggacgaatgccgg
cacggcaacggcccggtgctgatcgaggcgttcacctaccggatggacgcgcacaccacc
accgacgaccccacccgctaccggctctcggacgagctggaggagtggaagctcaaggac
ccgatcgagcgcgtgcgggcgttcctggctcgcaatgggcacgcggaccaggcgttcttc
gacagcgtccaggccgaggcggaccagttcgccgccgagctgcgcgactacacgttcaac
atgccggagccgccgccggaccgggtgttttcccaggtctacgccgaaccttcgccggtg
ctggaagcgcagcgcgaggagtatctgtcctatctcgacggtttcgccgcggcgggtgag
cactga
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