Arvicanthis niloticus (African grass rat): 117694157
Help
Entry
117694157 CDS
T08817
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00010
Glycolysis / Gluconeogenesis
anu00020
Citrate cycle (TCA cycle)
anu00620
Pyruvate metabolism
anu00785
Lipoic acid metabolism
anu01100
Metabolic pathways
anu01200
Carbon metabolism
anu01210
2-Oxocarboxylic acid metabolism
anu04066
HIF-1 signaling pathway
anu04922
Glucagon signaling pathway
anu05230
Central carbon metabolism in cancer
anu05415
Diabetic cardiomyopathy
Module
anu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
117694157 (Pdha1)
00020 Citrate cycle (TCA cycle)
117694157 (Pdha1)
00620 Pyruvate metabolism
117694157 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
117694157 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
117694157 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
117694157 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
117694157 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
117694157 (Pdha1)
Enzymes [BR:
anu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
117694157 (Pdha1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
117694157
NCBI-ProteinID:
XP_034340861
EnsemblRapid:
ENSANLG00005026208
LinkDB
All DBs
Position
X:29022395..29038438
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSEPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agcagagtgctggtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggcttaagtactacaggatgatgcagactgtgcgccggatggagctaaaggcagatcag
ctgtataagcagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgtgtgggcctggaggctggcataaaccccacggaccatcttatcactgcctaccgagct
catggcttcaccttcactcggggcctgcctgtccgagcaattcttgcagagctaacagga
cgaagagggggctgtgctaaagggaaaggcggatcaatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagcacaggtgcccctgggagcaggaattgctctggcc
tgcaagtacaatggaaaagatgaggtctgtttgacattatatggcgacggggctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaattaccttgtattttc
atctgtgagaataaccgctatggcatggggacatcggttgagagagcagcagccagcact
gattactacaaaagaggagattttattcctggactgagggtagatggaatggatatcctg
tgtgtccgagaggcaacaaagtttgcagctgcctattgtaggtctggtaaggggcccatc
ctgatggagctacagacttaccgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgtggaagaattaaaggagattgatgtg
gaagtgaggaaagaaatcgaggatgctgcccagtttgccacggctgatccagagccaccg
ctggaggagctaggctatcacatctacagcagtgagcctccctttgaagtacgtggtgcc
aaccagtggatcaagtttaagtcagttagttaa
DBGET
integrated database retrieval system
