Arvicanthis niloticus (African grass rat): 117694504
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Entry
117694504 CDS
T08817
Symbol
Araf
Name
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu01521
EGFR tyrosine kinase inhibitor resistance
anu01522
Endocrine resistance
anu04010
MAPK signaling pathway
anu04012
ErbB signaling pathway
anu04068
FoxO signaling pathway
anu04270
Vascular smooth muscle contraction
anu04650
Natural killer cell mediated cytotoxicity
anu04720
Long-term potentiation
anu04726
Serotonergic synapse
anu04730
Long-term depression
anu04810
Regulation of actin cytoskeleton
anu04910
Insulin signaling pathway
anu04914
Progesterone-mediated oocyte maturation
anu04928
Parathyroid hormone synthesis, secretion and action
anu05010
Alzheimer disease
anu05022
Pathways of neurodegeneration - multiple diseases
anu05034
Alcoholism
anu05160
Hepatitis C
anu05161
Hepatitis B
anu05200
Pathways in cancer
anu05205
Proteoglycans in cancer
anu05208
Chemical carcinogenesis - reactive oxygen species
anu05210
Colorectal cancer
anu05211
Renal cell carcinoma
anu05212
Pancreatic cancer
anu05213
Endometrial cancer
anu05214
Glioma
anu05215
Prostate cancer
anu05218
Melanoma
anu05219
Bladder cancer
anu05220
Chronic myeloid leukemia
anu05221
Acute myeloid leukemia
anu05223
Non-small cell lung cancer
anu05224
Breast cancer
anu05225
Hepatocellular carcinoma
anu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117694504 (Araf)
04012 ErbB signaling pathway
117694504 (Araf)
04068 FoxO signaling pathway
117694504 (Araf)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
117694504 (Araf)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
117694504 (Araf)
09152 Endocrine system
04910 Insulin signaling pathway
117694504 (Araf)
04914 Progesterone-mediated oocyte maturation
117694504 (Araf)
04928 Parathyroid hormone synthesis, secretion and action
117694504 (Araf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
117694504 (Araf)
09156 Nervous system
04726 Serotonergic synapse
117694504 (Araf)
04720 Long-term potentiation
117694504 (Araf)
04730 Long-term depression
117694504 (Araf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117694504 (Araf)
05205 Proteoglycans in cancer
117694504 (Araf)
05208 Chemical carcinogenesis - reactive oxygen species
117694504 (Araf)
09162 Cancer: specific types
05210 Colorectal cancer
117694504 (Araf)
05212 Pancreatic cancer
117694504 (Araf)
05225 Hepatocellular carcinoma
117694504 (Araf)
05226 Gastric cancer
117694504 (Araf)
05214 Glioma
117694504 (Araf)
05221 Acute myeloid leukemia
117694504 (Araf)
05220 Chronic myeloid leukemia
117694504 (Araf)
05218 Melanoma
117694504 (Araf)
05211 Renal cell carcinoma
117694504 (Araf)
05219 Bladder cancer
117694504 (Araf)
05215 Prostate cancer
117694504 (Araf)
05213 Endometrial cancer
117694504 (Araf)
05224 Breast cancer
117694504 (Araf)
05223 Non-small cell lung cancer
117694504 (Araf)
09172 Infectious disease: viral
05161 Hepatitis B
117694504 (Araf)
05160 Hepatitis C
117694504 (Araf)
09164 Neurodegenerative disease
05010 Alzheimer disease
117694504 (Araf)
05022 Pathways of neurodegeneration - multiple diseases
117694504 (Araf)
09165 Substance dependence
05034 Alcoholism
117694504 (Araf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117694504 (Araf)
01522 Endocrine resistance
117694504 (Araf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
anu01001
]
117694504 (Araf)
Enzymes [BR:
anu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117694504 (Araf)
Protein kinases [BR:
anu01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
117694504 (Araf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
TUG-UBL1
Kdo
Motif
Other DBs
NCBI-GeneID:
117694504
NCBI-ProteinID:
XP_034341336
EnsemblRapid:
ENSANLG00005020774
LinkDB
All DBs
Position
X:complement(606810..618380)
Genome browser
AA seq
605 aa
AA seq
DB search
MEPPRNPPVSGAEPSRAVGTVKVYLPNKQRTVVTVREGMTVYDSLDKALKVRGLNQDCCV
VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEAPSNLSVNELL
TPQGPSSFPQHRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPVDSSLMQFTTQSFS
TDAAGRSGGDGAPRGSPSPASVSSGRKSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGY
YWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKT
RHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH
AKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQ
DPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKA
MRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSA
ARLVP
NT seq
1818 nt
NT seq
+upstream
nt +downstream
nt
atggaaccaccacgaaaccctcctgttagtggggctgagccatctcgggcagttggcact
gtcaaagtatacctgcctaacaagcaacgcacggtggtgactgtccgggaaggcatgact
gtctatgactctttggacaaggccctcaaggtgcggggcctcaatcaggactgctgtgtg
gtctacagactcatcaaaggaagaaagacagtcactgcctgggacacagccattgcacct
ttggatggtgaagagctcattgtggaggtcctggaagatgtgccgctgaccatgcacaat
tttgtccggaagacgttcttcagcctggccttctgtgacttctgccttaagtttctgttc
catggattccgctgccagacctgtggctacaagttccaccagcattgttcctccaaggtt
cccaccgtctgcgttgacatgagtaccaaccgccgacagttctaccacagcatccaggat
ttgtctggaggctccaggcagcaggaggctccctcaaatctctctgtgaatgagctgcta
accccccagggtcccagctcctttccccagcaccgtgaccaggagcacttctccttccct
gcccctgccaatcccccactgcagcgcatccgttccacatctactcctaacgtccacatg
gtcagcaccacagctcccgtggactccagcctcatgcagtttactactcagagcttcagc
accgatgctgctggcagaagtggtggtgacggagcccctcggggtagccctagcccagct
agtgtgtcttcagggaggaagtccccacattccaagttaccttcagaacagcgggagcgg
aagtccttggcagatgaaaagaaaaaagtgaagaacctggggtaccgggactcaggctat
tactgggaggtgccacccagtgaggtacagctgttgaagaggatcgggacaggctctttt
ggcactgtgtttcgggggcgttggcatggcgatgtagctgtgaaggtactcaaggtggcc
caacctaccgctgagcaggcccaggccttcaagaatgaaatgcaggtgctcaggaagaca
cgacatgtcaacattttgctgttcatgggtttcatgactcggccagggtttgccatcatc
acacagtggtgtgagggttccagcctctaccaccacctacatgtggctgacacgcgcttt
gacatggtccagctcattgacgtggcccggcagactgcccagggcatggactacctccac
gccaagaacatcattcaccgagacctaaagtccaacaatatcttcctacatgaggggctc
acagtcaagattggtgacttcggcctggccacggtgaagacacggtggagtggggcccag
cccttagagcagccctcggggtctgtgctatggatggcagctgaggtgatccgtatgcag
gacccgaacccctacagcttccagtcggatgtctatgcctatggtgttgtgctgtatgag
cttatgaccggctcactgccctacagccacattggcagccgtgaccagatcatctttatg
gtgggccgtggctatctgtctccggacctcagcaaaatcttcagtaattgccccaaagcc
atgaggcgcctgctgactgactgcctcaagttccagcgggaggagcggcccctatttccc
cagattctggccacgatcgagctactgcagcggtcactccccaagattgagcggagtgcc
tccgaaccatccttgcaccgcacccaggctgatgagttgcctgcctgccttctcagcgca
gcccgccttgtgccttag
DBGET
integrated database retrieval system