KEGG   Arvicanthis niloticus (African grass rat): 117717401
Entry
117717401         CDS       T08817                                 
Symbol
Tph1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
anu  Arvicanthis niloticus (African grass rat)
Pathway
anu00380  Tryptophan metabolism
anu00790  Folate biosynthesis
anu01100  Metabolic pathways
anu04726  Serotonergic synapse
Module
anu_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:anu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    117717401 (Tph1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    117717401 (Tph1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    117717401 (Tph1)
Enzymes [BR:anu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     117717401 (Tph1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT zf-C2HE ACT_4 DUF262
Other DBs
NCBI-GeneID: 117717401
NCBI-ProteinID: XP_034370568
EnsemblRapid: ENSANLG00005009029
LinkDB
Position
1:complement(20342788..20360439)
AA seq 444 aa
MIEDNKENKDHSSDRGRVTLIFSLKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFPLLKSHTTVLSVDSPDQLTVKEDVMDTVPWFPKKISDLDFCAN
RVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPRIEFTEEEIKTWGTIFRE
LTKLYPTHACREYLRNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKVAC
KQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDTKSIASA
VDELRYDLDVVSDALAKVSRWPSV
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgattgaagacaacaaggagaacaaagaccattcctctgatcgggggagagtgactctc
atcttttccttgaagaatgaagttggaggactcataaaagcactgaaaatcttccaggag
aatcatgtgaacctgttacatattgagtcccggaaatcaaagcgaagaaattcagaattt
gagatttttgttgactgtgacatcaaccgagaacagctgaatgacatctttcccctgctg
aagtcccacaccactgtcctctccgtggactcgcccgatcagctcaccgtgaaggaagat
gttatggacactgtcccttggtttccaaagaagatttctgacctggacttctgcgccaac
agagtgctgttgtacggatccgaactcgacgcggaccaccctggcttcaaagacaatgtc
taccgtagaagacgaaagtatttcgcagagttggctatgaactacaaacatggggacccc
attcccaggattgaattcacagaagaagagattaagacctggggaaccatcttccgagag
ctaaccaaactctacccgacccacgcctgcagagagtacctcagaaaccttcctttgctc
tcaaaatactgtggctatcgggaagataacatcccacaactggaagatgtctccaacttt
ttaaaagaacgcacagggttttccatccgtcctgtggctggttacctctcaccgagagat
ttcctgtcggggttagcctttcgagtctttcactgcactcagtacgtgagacacagttca
gatcctctctatactccagagccagacacctgccatgaactcttaggccatgttcctctc
ttggctgaacccagttttgctcaattctcccaagaaattggcctggcatcccttggagct
tcagaggagactgttcaaaaattggcaacgtgctactttttcactgtggagtttgggctg
tgcaaacaagatggacagctgagagtctttggtgccggcttgctttcttccatcagtgag
ctcaaacatgcactttctggacatgccaaagttaagccttttgatcccaaagttgcctgc
aaacaggaatgtctcatcacaagcttccaggatgtctactttgtatctgagagctttgaa
gacgcaaaggagaagatgagagaatttgccaagaccgtgaaacgcccgtttggagtgaag
tacaatccatacacacagagcatccaggttctgagagacaccaagagcatagctagcgcc
gtggatgagttgcggtatgacctcgatgtcgtcagcgatgcgcttgctaaggtcagcagg
tggcccagtgtgtga

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