Amycolatopsis keratiniphila: AORI_1985
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Entry
AORI_1985 CDS
T02678
Symbol
folC
Name
(GenBank) dihydrofolate synthase / folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
aoi
Amycolatopsis keratiniphila
Pathway
aoi00790
Folate biosynthesis
aoi01100
Metabolic pathways
aoi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aoi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AORI_1985 (folC)
Enzymes [BR:
aoi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AORI_1985 (folC)
6.3.2.17 tetrahydrofolate synthase
AORI_1985 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGM04573
UniProt:
R4T1L0
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Position
2135963..2137639
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AA seq
558 aa
AA seq
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MPRGDGRDSEDFRESPDLADLDSFAGVDELGARAHDPSDDTDPDLDAPDAAYQAGGGARG
GIGGIGQLGDNLALGPVPDLVAPEDVELHELDDQGDAFAPSDPNGQQARRELLAVEAELN
QRWPETKIEPSLARIAALVNLMGEPHRGYPVLHVAGTNGKGSTTRMIDALLTRMGLRVGR
YTSPHLQLVTERIALDGAPISAAAYVDLYRDVAPYVTMVDNAGGQDAVPMSKFEVLTGMA
FAAFADAPVEAAVIETGLGGSWDATNVVDGDVAVITPIGVDHVEYFGGSPVKAAVEKAGI
IKPGSVAVIAEQDPEVQKVLLERAIEVDASVARAGSEFGVLEREVAVGGQMLKLQGLGGV
YDEIFLPLHGAHQAANAALALAAVEAFFGAGKDKQLVIEAVREAFAEVETPGRLERVRAA
PTVLLDAAHNPHGAKALATTVAEEFAFRRLAAVVGVMAEKDARGILDALEPVVSEIVVTK
NSSPRAMPLDELNDIAISIFGEDRVVAEPSLDAAIETAIGLVEQSDDPEEPLAGGGVLVT
GSVVTAGEARTLFGKEPA
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcgaggtgacggccgggattccgaagatttcagggaatccccggacctggcagat
ctggacagtttcgccggtgtcgacgaattgggggcccgcgcccacgatccgtccgacgac
accgacccggatctggacgcacccgacgccgcgtaccaggcgggcggcggtgcgcggggc
ggcatcggcgggatcgggcagctgggggacaacctcgcgctcggccccgtgccggacctc
gtcgccccggaggacgtggaactgcacgaactggacgaccagggcgacgcgttcgccccg
tccgaccccaacgggcagcaggcccgccgggaactgctcgccgtcgaggccgagctgaac
cagcgctggcccgagaccaagatcgagccgtccctcgcccggatcgcggccctggtcaac
ctcatgggtgaaccgcaccgcggttacccggtgctgcacgtcgccgggaccaacggcaag
ggctcgaccacccggatgatcgacgcgctgctgacccgcatgggcctgcgcgtcggccgg
tacacgagcccgcatctgcaactcgtcaccgagcggatcgcgctcgacggcgcccccatc
tccgccgccgcgtacgtcgacctgtaccgcgacgtcgcgccgtacgtgaccatggtggac
aacgccggcggccaggacgcggtgccgatgagcaagttcgaggtgctcaccgggatggcg
ttcgcggccttcgccgacgcgcccgtcgaagccgcggtcatcgagaccgggctcggcggc
tcttgggacgccaccaacgtcgtggacggcgacgtcgccgtcatcacaccgatcggcgtc
gaccacgtcgagtacttcggcggctccccggtcaaggccgcggtggagaaggccgggatc
atcaagcccggcagtgtcgcggtcatcgcggagcaggaccccgaagtgcagaaggtcctg
ctggaacgcgccatcgaggtcgacgcgagcgtcgcccgcgcgggcagtgagttcggcgtg
ctggagcgcgaggtcgccgtcggcgggcagatgctgaaactgcagggcctcggcggggtc
tacgacgagatcttcctgccgctgcacggcgcgcaccaggccgccaacgccgcgctggcg
ctggccgccgtcgaagcgttcttcggcgcgggcaaggacaagcaactggtcatcgaggcc
gtacgcgaggccttcgccgaggtcgagacccccggtcggctggagcgcgtccgcgccgcc
ccgaccgtgctgctcgacgccgcccacaacccgcacggcgcgaaggcactcgcgaccacc
gtcgccgaggagttcgccttccgccgcctcgccgccgtggtcggcgtgatggcggagaag
gacgcgcgcggcatcctggacgccctcgaaccggtggtgtccgagatcgtcgtcaccaag
aactcttccccgcgcgcgatgccgctcgacgaactcaacgacatcgccatctcgatcttc
ggcgaagaccgggtcgtggccgagcccagcctggacgccgcgatcgagaccgccatcggc
ctcgtcgagcagagcgacgaccccgaggaaccactggcgggcggcggcgtgctggtcacc
ggctccgtcgtcaccgcgggcgaggccaggaccctgttcggtaaggagccggcgtga
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