Actinobacillus pleuropneumoniae AP76 (serotype 7): APP7_0677
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Entry
APP7_0677 CDS
T00717
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
apa
Actinobacillus pleuropneumoniae AP76 (serotype 7)
Pathway
apa00790
Folate biosynthesis
apa01100
Metabolic pathways
apa01240
Biosynthesis of cofactors
Module
apa_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
apa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
APP7_0677 (folC)
Enzymes [BR:
apa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
APP7_0677 (folC)
6.3.2.17 tetrahydrofolate synthase
APP7_0677 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACE61329
UniProt:
B3H160
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Position
752755..754059
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AA seq
434 aa
AA seq
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MMNTLTVPTINDSLAIWLDYLEKSHFKPIDMGLERIKGVAQELDLLQPAPYVITVAGTNG
KGSTCRLLEVALLKAGYRVGVYSSPHLIRYNERVRIQGDLLNDEAHVQSFVKIQQKKTAS
LTYFEFSTLSALQLFKDTNLDIVILEVGLGGRLDATNIVDPNLAVITSIDIDHVEFLGDN
REDIGREKAGIFRENIPVIIGEPDCPRSILQQAKALNCQVVRRNINWKYSVENNHFHWQS
ESIDWQDLPMPQIPIPNAGTALAALAQLPFEINEQVVRAALQEAQMTARFQTLNEQNFAN
FSGKRPLAQVIIDVGHNPHAAKYLAGRLTSLKQPNQKIYAVFSALVDKDLSGIVEPLENV
IDEWHCAGLAGYRGQSGEAVYQKLANVLPNSTACYYRTVPEAAESLFAKTSKTDIILIFG
SFHTVSDFLVWVEQ
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgatgaatactttaactgttccgactattaatgatagcctcgccatatggttggattac
ttagaaaaatcacattttaagccgattgatatgggcttagaacgcattaaaggcgtagca
caagaattagacttacttcaaccagcgccttatgttatcaccgttgccggtactaacggt
aagggttcaacttgtcgtttattagaagtagctttgctaaaagccggttatcgagtcggt
gtctattcatcgcctcacctaattcgttataacgaacgggtaagaattcaaggcgactta
ctcaatgacgaagcgcacgtgcaatcatttgtaaaaatccaacaaaaaaagaccgcttct
ttaacttattttgagtttagtacgctttcggcattacaactttttaaagatacaaattta
gatattgtgattttagaagttggacttggcggacgtttagatgcaaccaatattgttgat
ccgaatttagctgtcatcacatctattgatattgatcacgttgagtttcttggtgataac
cgagaagatatcggtcgagaaaaagcaggcattttccgtgaaaatataccggtgattatc
ggtgaaccggattgtccgaggagcattttacagcaagcgaaagcacttaattgccaagtg
gttagacgcaatataaattggaaatattccgtagaaaataaccacttccactggcaatcg
gaatctattgattggcaagatttaccgatgccgcaaattccgattccgaatgccggtacc
gctttagccgcgttggctcaacttccgtttgaaattaatgaacaagtggttagagccgca
ctgcaagaagcgcaaatgaccgctcgtttccaaacgctaaacgaacaaaattttgcaaac
ttttccggaaaacgaccgcttgcccaagtgattattgatgtcggacacaatccgcatgcg
gcaaaatatttagcagggcgactaacgtcactgaaacagccgaatcaaaagatttatgcg
gtatttagcgcattagttgataaagacttaagcggcatcgtagagccattagaaaatgtg
attgacgaatggcattgtgccggtttagccggatatcgagggcagtcaggtgaagcggtc
tatcaaaaactggcaaatgttttaccaaattcgaccgcttgttattaccgaaccgttccc
gaagcggctgaatcattattcgccaaaacgagcaaaaccgacattatcctgattttcggc
tcattccacaccgtgagcgattttttggtttgggttgaacagtaa
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