Ahaetulla prasina (Asian vine snake): 131195291
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Entry
131195291 CDS
T09329
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
apri
Ahaetulla prasina (Asian vine snake)
Pathway
apri00270
Cysteine and methionine metabolism
apri00480
Glutathione metabolism
apri01100
Metabolic pathways
apri01240
Biosynthesis of cofactors
apri04216
Ferroptosis
Module
apri_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
apri00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
131195291 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
131195291 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
131195291 (GCLC)
Enzymes [BR:
apri01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
131195291 (GCLC)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
131195291
NCBI-ProteinID:
XP_058033071
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All DBs
Position
1:142307680..142339629
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AA seq
636 aa
AA seq
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MGLLSQGSPLSWEKTQRHAEHVRKHGIQQFLHIYRAVGERHKDVLKWGDEVEYMLVAFDH
KNKRARLLLTGEEVLHTLQEKGERINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKKDEVVCTVTSFPRLGCPGFTIPEYHPTPIEMGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPSDDGEAARAAKPDHVYMD
AMGFGMGNCCLQVTFQACSIFEARYLYDQLATICPIVMALSAAAPFYRGYVTDIDCRWGV
ISASVDDRTREERGLEPLKNNRFRINKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEHLV
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDISKGGNAVVDGCGATQNGTETDVEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVANHPEYKHDSVISEEMNY
SLMWKCNQIAQEQVECPELLGVGLNKLKYSGIKATS
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctcctgtcgcaaggctcgccgctcagctgggagaagacgcagcggcacgcggag
cacgtgcgcaaacacggcatccagcagttcctgcacatctaccgggccgtcggggagagg
cacaaggacgtgctcaagtggggtgacgaggtggaatatatgttggtagcctttgaccat
aaaaataagagagcacggttgttattaactggagaagaagtacttcatactttacaagaa
aaaggtgaaagaataaatccaaaccatccaacattatggagaccagagtatggaagctac
atgatcgaagggactcctgggcagccatatggaggaacaatgtctgaatttaacactgta
caggataacatgaggaagcggcgccaggaagctgcttcagtattaaaaaaagatgaagtt
gtttgcactgtcacatcatttccaagattaggttgtccaggatttacgataccagagtat
catccaacacctattgagatgggagcctcaaagtctcttttcttcccagatgaggctata
aacaaacatcccaggtttagtactttaacgagaaatattcgacatagaagaggcgaaaaa
gtagttataaatgtaccaatatttaaggacaagaataccccatcaccgtttatagaaaca
tttcctagtgatgatggtgaagcagcaagagcagctaagcccgatcatgtatatatggat
gccatgggatttggcatgggcaattgttgccttcaggtaacattccaggcctgcagcatt
tttgaagcaagatatctttatgatcagctagccacaatctgtcccattgtgatggcttta
agtgctgcagctcctttttacagaggctatgtgacagatattgattgccgttggggagtt
atatctgcatcagtagatgacaggacaagagaggagaggggtctagagccattgaagaac
aaccgtttcagaatcaataaatccagatacgattccatagacagttatctctcagaatgc
ggtgaaaaatacaatgacattgatttgacaatagataaagaaatctatgagcatctagta
aaagagggcattgatcatcttttggcacaacacattgctcacttatttattcgtgaccct
ttgacactgtttgaagaaaaaattcatctggatgatgcaaatgaatctgatcattttgag
aatattcagtcaacaaattggcagacaatgagatttaagccacctcctccaaattcagat
attggatggagagttgagttcagaccaatggaggtccagttaacagacttcgaaaactca
gcatatgttgtatttgttgtactattaactcgagtcattctctcatacaaattggatttt
ctcattcctttgtcaaaggtggatgaaaacatgaaagtagctcagaaacgagatgctgtc
cgacagggcatgttttattttagaaaagacatttctaaaggtggcaatgcagttgtggat
ggatgtggtgcaactcaaaatggtacagaaacagatgtagaagaatatacgttaatgagc
atagatacaataattaatggaaaggaaggagtatttccaggattaattccaattttaaac
tcttaccttgaaaatatggaagtggatgtggatacaagatgcagcatcctaaactatctg
aaactaataaaaaaaagagcatcaggcgaattaatgacagctgctagatggatgcgagaa
tttgttgcaaaccatccagaatacaagcatgatagtgtgatctcagaagagatgaattac
agcctgatgtggaaatgcaaccaaattgcacaagagcaagttgaatgtcctgagctgctt
ggagtgggcttaaataaactaaagtacagtggaattaaagccacttcttaa
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