Aspergillus puulaauensis: APUU_40975S
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Entry
APUU_40975S CDS
T08081
Symbol
LYS2
Name
(RefSeq) putative NRPS-like protein biosynthetic cluster
KO
K00143
L-2-aminoadipate reductase [EC:
1.2.1.95
]
Organism
apuu
Aspergillus puulaauensis
Pathway
apuu00300
Lysine biosynthesis
apuu01100
Metabolic pathways
apuu01110
Biosynthesis of secondary metabolites
apuu01230
Biosynthesis of amino acids
Module
apuu_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:
apuu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
APUU_40975S (LYS2)
Enzymes [BR:
apuu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.95 L-2-aminoadipate reductase
APUU_40975S (LYS2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NAD_binding_4
AMP-binding
Epimerase
Condensation
PP-binding
3Beta_HSD
RmlD_sub_bind
NAD_binding_10
AMP-binding_C
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
64974536
NCBI-ProteinID:
XP_041556725
LinkDB
All DBs
Position
4:join(2431545..2431916,2431966..2435233,2435313..2435637,2435733..2436036)
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AA seq
1422 aa
AA seq
DB search
MGVESVPLQERLERWAQRLQNLTVSPLTRDYPDNQNQELPKRAIEAFESLKLSNETSSAL
QKLSSTSSGFTVFLTAFVVLVARLTGDEDIAIGTSAGEDGRPFVLRVPIDTSETFLQLLS
KVQKAYDEGSSEIVPLGSLRSHIQEKSQSERSPILFRFAAYDAPAASQDYPANTFETTDL
VVNVAPASTSDRSTELGAYYSQRLFSSARISTILNQLTQLVQNATSNPETAIGRIDFMTP
EQRALLPDPTADLHWSKFRGAIHDIFSENAQSHPDKLCVVETKSATSAHREFTYRQINEA
SNILGHHLVQAGVERGDVVMVYAYRGVDLVVAVMGILKAGATFSVIDPAYPPERQCIYLD
VARPRALINIAKATKDAGELSEIVRTFIGENLELRTEIPALALLDDGTLLGGSIDGQDVL
EKQVPLKSKSVGVVVGPDSTPTLSFTSGSEGRPKGVRGRHFSLAYYFPWMAETFKLNPND
KFTMLSGIAHDPIQRDIFTPLFLGAQLLVPAREDIQNERLAEWMRDYGASVTHLTPAMGQ
ILVGGASAQFPTLHHAFFVGDILIKRDCRSLQGLAPNVNIVNMYGTTETQRAVSYFEVPS
YSSDGGYLDTMKDVIPAGRGMLDVQMLVVNRFEPSRICAIGEVGEIYVRAAGLAEGYLGS
PELSQKKFLTNWFVDPKTWADKDAAESQGTNEPWREFYVGPRDRLYRSGDLGRYTPSGDV
ECSGRADDQVKIRGFRIELGEIDTHLSRHPLVRENVTLVRRDKFEEPTLVSYFVPDMGKW
ASWLEQKGLKDDDSAEGMVGMLRRFRPLRDDVRDLLRSKLPTYAVPTVFIPLKRMPLNPN
GKIDKPALPFPDTAELSAAAPQRRPSALKSLSETEQALAQIWANRIANVTAPMIGPEDSF
FDLGGHSILAQQMFFDLRRKWRGIDISMSAIFRSPTLRAFAAEIDRLLNFESFASNDDAA
ETAAVANEPDDEYSRDARKLVDTLPKTFPARTEDILSTEPTIFLTGATGFLGAHILRDLL
TRKSPSARVVALVRGKSAEQALARVRSTCRAYGFWEESWASRLECICGSLGDARFGLTEE
AWDGLTNRVDAVIHNGALVHWVYPYSTLKPANVLGTIDALKLCATGKPKQFSFVSSTSVL
DSDHYVLESERSIAGGGAGISEDDDLEGSSVGLGTGYGQSKWAGEYLVREAGKRGLKGTI
VRPGYVLGDSNSGTTNTDDFLIRMVKGCIQLSARPNINNTVNMVPVDHVARVVIAGAFRP
TVSPIGVAQVTGHPRLRFNQFLGALQLYGYDVPQVDYVPWSKSLEQYVNSGEHDDPESQH
ALMPLYHFVTADLPSNTKAPELDDVHAAASLRADAAWSGVDASAGAGVTEELVGLYASYL
VSVGFLPAPSASTAGARPLPAVTITDDQKEAMAGVGGRGGAA
NT seq
4269 nt
NT seq
+upstream
nt +downstream
nt
atgggtgtcgaatccgttccattgcaggaacgccttgagcgctgggctcaaaggctacaa
aacctcaccgtctccccactaacccgcgattatcccgacaaccagaaccaagagctgccc
aagagggccattgaggctttcgagtcccttaagctctccaatgagacatcatccgcgtta
caaaaactatccagcacatcttcaggattcacagttttcctgactgcgttcgttgtactc
gtcgctcgtttgactggtgatgaggatatcgccattggcacaagcgctggtgaagatggc
cggcccttcgtcctgagagtgccaattgatacctcagagacattccttcagctgctctcc
aaagttcaaaaggcctacgatgaggggtcatccgagatcgtgccattgggcagtttacga
tcccacatccaagagaaatcgcaatccgagcgatccccaatcctcttccgcttcgccgca
tacgatgctcccgctgcctcccaagactaccccgccaatacctttgagacaacggatttg
gtggtcaatgttgcgcccgcaagcacctcggaccggtcgacggagctgggagcatactat
agtcagagactgttctccagtgccagaataagcacaattttgaaccagttaactcagctg
gttcagaatgctacaagcaacccagaaacggcaattgggcgcattgatttcatgaccccc
gagcagcgagcccttcttccagaccccaccgcagacctacattggtccaagtttcgaggg
gctatccacgacatcttctccgagaacgctcaaagtcacccggacaagctttgcgttgtc
gaaaccaagtccgccacttccgcccaccgcgagttcacctaccgtcagattaatgaggcg
tcgaacattctcggtcaccacctggttcaagcaggtgttgagaggggcgacgttgtcatg
gtctacgcttaccgcggcgttgacctggtcgtggctgtcatgggtattcttaaggccggt
gcgacattttccgttatcgatcctgcataccctcctgagagacaatgcatttacctcgat
gtggctcgtcctcgggcattgattaacattgcgaaggctactaaggatgcaggcgagctg
tctgaaatagtacgcacatttatcggtgagaacctagagcttcgaactgagattcctgcg
ctcgccttgcttgacgacggtaccctcctgggaggctcgattgatggacaggatgtcctg
gaaaagcaggtgcctttgaagtctaagtctgtcggcgtcgtcgttggtcctgattctact
ccaactctgtcgttcacctcaggctccgaaggtagacccaagggtgtcagaggtcgccat
ttctccttggcgtactatttcccatggatggcggagacattcaagctgaaccctaacgac
aagttcacaatgctcagcggaattgcccatgaccccatccaaagagatatcttcacccct
cttttcttgggagctcagctacttgtacccgcgcgcgaggatatccagaacgaaaggctg
gccgagtggatgcgcgattatggcgctagtgtcacccatcttacacctgccatgggtcaa
attcttgtgggaggtgcttccgcacagttccctactctccaccacgctttcttcgtcgga
gacatcctgattaagagagactgtcgctctctacaagggctggcgccgaacgtcaacatc
gttaacatgtatggaaccaccgagacgcaacgtgctgtcagttacttcgaggtcccgagt
tactcgagcgacggcggatacttggacaccatgaaggatgtgatcccggctggacgcgga
atgctcgatgtgcagatgctggttgtcaaccgcttcgagcctagccgtatctgcgctatc
ggcgaagtgggtgagatctacgttcgtgcggctggtcttgcggaagggtaccttggttcg
cctgaactcagccagaagaagttcctcaccaactggttcgttgatcctaagacgtgggcg
gacaaggatgctgcggagtcgcaaggcaccaatgagccctggagggagttctacgttgga
cctagggaccgtttgtaccgcagcggtgaccttggcagatacactccatctggagatgtc
gagtgctcaggccgtgccgatgatcaagtgaagatccgtggtttccgtatcgagttgggt
gaaatcgatacccatctctcccgtcatcctcttgttagagagaatgtgacgttggtccgt
cgagacaagtttgaggagcccactcttgtcagctactttgtacctgatatgggcaagtgg
gcttcgtggctagagcagaagggcttgaaggatgacgactccgctgaaggaatggttggc
atgctaagacgattccgcccacttcgtgatgatgttcgcgacctactccgcagcaagctc
cccacctacgctgtgcccaccgtctttattccgctcaagcgaatgccgctcaaccctaac
ggaaagattgacaagcctgctttgccgttccctgatactgcagagctcagcgctgcagct
cctcaacgcaggccatcagccttgaagtccctttcagagactgagcaggccctggcacag
atctgggctaatcggattgccaatgtcactgcccccatgatcggccccgaagattcattc
tttgaccttggaggccacagtatcctcgcgcaacagatgttctttgatctacgacgtaag
tggcgtggcatcgacatcagcatgagtgccattttccgcagccctaccctccgcgccttc
gctgcggagatcgatcgcctgctgaacttcgaatccttcgccagcaacgatgacgccgct
gaaaccgctgccgtagctaacgagcctgatgacgaatactcccgcgatgcccgcaagttg
gtcgataccctacccaagaccttcccggctcgcacagaagacatcctttccaccgaaccc
acgatcttcctcactggtgctaccggcttcctcggcgcgcacatcctccgagaccttctc
acccgcaagtctccgtccgcaagggttgtcgcgcttgtccgtggcaagagcgccgagcaa
gcccttgcccgcgtccgctcaacctgccgagcctacggcttctgggaagaatcctgggct
tcccgcctcgaatgcatctgcggttctctcggcgatgcccgcttcggactcactgaagaa
gcctgggatggcctgaccaaccgcgtcgacgcagtcatccacaacggcgccctcgtccac
tgggtctatccctactccacactcaagccagccaacgtccttggtaccatcgatgccctg
aagctctgtgcaaccggtaaacccaagcagttctcctttgtcagttcaactagtgtcctc
gatagcgaccactacgtcctggaatccgagcgcagcatcgccggcggcggggcgggtatc
agcgaagacgatgacctagagggtagcagcgtcggtctaggaacgggctacggccagagc
aagtgggccggcgagtaccttgtccgtgaagcaggcaagcgcggactgaaggggaccatc
gtccgtcctggttacgtactaggtgattcaaacagcggaacaacgaacaccgatgacttc
ctcattcgcatggtcaagggttgcatccagctttccgcgcgcccgaacatcaacaatacg
gtcaacatggttcccgttgaccacgtcgcgcgtgtcgtgattgccggtgccttccgaccc
accgtctcgcctatcggagtcgcacaagtaacaggccacccacgcctgcgtttcaaccag
ttcctcggtgcgctccagctgtacgggtatgatgttccgcaggtcgactacgtgccgtgg
tcgaagtcgctggagcagtatgtgaatagcggggagcacgatgacccggagtcgcagcat
gctttgatgccattataccatttcgtcacggcggacttgccgtctaatactaaggcgcct
gagttggatgacgtccatgcggctgcttcgttacgtgctgatgccgcgtggtcgggcgtt
gacgcctctgcgggtgccggtgtgacggaagagctagtcggtctctacgcctcttatctt
gtgtccgttggcttcctaccagcgccatcagcgtcgaccgcgggagcgcgtccgctgccc
gccgttacgattactgatgatcagaaggaggcaatggcaggcgttggtggccgtggcggt
gctgcttga
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