Amycolatopsis roodepoortensis: NQK81_12585
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Entry
NQK81_12585 CDS
T08507
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
aroo
Amycolatopsis roodepoortensis
Pathway
aroo00790
Folate biosynthesis
aroo01100
Metabolic pathways
aroo01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aroo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NQK81_12585
Enzymes [BR:
aroo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NQK81_12585
6.3.2.17 tetrahydrofolate synthase
NQK81_12585
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UUV34242
LinkDB
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Position
complement(2699880..2701556)
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AA seq
558 aa
AA seq
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MPRGDGRDSEDFRESPDLADLDSFAGVDELGARAHDPSDDTDPDLDAPDAAYQAGGGSRG
GIGGIGQLGDNLALGPVPDLVAPEDVELHELDDQGDEFAPADPNGQQARRELLAVEAELN
QRWPETKIEPSLARIAALVNLMGEPHRGYPVLHVAGTNGKGSTTRMIDALLTRMGLRVGR
YTSPHLQLVTERIALDGAPISAAAYVDLYRDVAPYVTMVDNAGGPDAVPMSKFEVLTGMA
FAAFADAPVEAAVIETGLGGSWDATNVVDGEVAVITPIGVDHVEYFGGSPAKAAVEKAGI
IKPGSVAVIAEQEPEVQKILLERAVEVDASVARAGSEFGVLEREVAVGGQMLKLQGLGGV
YDEIFLPLHGAHQAANAALALAAVEAFFGAGKDKQLVIEAVREAFAEVETPGRLERVRAA
PTVLLDAAHNPHGAKALATTVAEEFAFRRLVAVVGVMAEKDARGILDALEPVVSEIVVTK
NSSPRAMPLDELNDIAISIFGEDRVVAEPSLDAAIETAIGLVEQSDDPEEPLAGGGVLVT
GSVVTAGEARTLFGKEPA
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcgaggtgacggccgggattccgaagatttcagggaatccccggacctggcagat
ctggacagtttcgccggtgtcgacgaattgggggcccgcgcccacgatccgtccgacgac
accgacccggatctggacgcacccgacgccgcgtaccaggcgggcggcggttcacggggc
ggtatcggcgggatcgggcagctgggggacaacctcgcgctcggccccgtgccggacctc
gtcgcccccgaggacgtggagctgcacgaactggacgaccagggcgacgagttcgccccg
gccgacccgaacgggcagcaggcgcgccgcgaactgctcgccgtcgaggccgagctgaac
cagcgctggcccgagaccaagatcgagccgtccctcgcccggatcgcggccctggtcaac
ctcatgggtgaaccgcaccgcggctacccggtgctgcacgtcgccgggaccaacggcaag
ggctcgaccacccggatgatcgacgcgctgctgacccggatgggcctgcgcgtcggccgg
tacacgagcccgcacctgcagctggtcaccgaacggatcgcgctcgacggcgcccccatt
tccgccgccgcgtacgtcgatctgtatcgcgacgtcgcgccgtacgtgaccatggtggac
aacgcgggcgggcccgacgcggtgccgatgagcaagttcgaggtgctcaccgggatggcg
ttcgcggccttcgccgacgcgcccgtcgaagccgcggtcatcgagaccgggctcggcggc
tcctgggacgccaccaacgtcgtggacggtgaagtcgccgtcatcaccccgatcggcgtc
gaccacgtcgagtacttcggcggctctccggccaaggccgcggtggagaaggccgggatc
atcaagcccggcagcgtcgcggtcatcgccgagcaagagcccgaagtgcagaagatcctg
ctggaacgcgccgtcgaggtcgacgcgagcgtcgcccgcgccggcagcgagttcggcgtg
ctggagcgcgaggtcgccgtcggcgggcagatgctgaagctgcagggcctcggcggggtg
tacgacgagatcttcctgccgctgcacggtgcgcaccaggccgccaacgccgcgctcgcg
ctggccgccgtcgaagcgttcttcggggcgggcaaggacaagcaactggtcatcgaggcc
gtccgcgaggccttcgccgaggtcgaaaccccgggaaggctggagcgcgtgcgcgccgca
ccgaccgtgctgctcgacgccgcccacaacccgcacggcgccaaggcgctcgcgaccacc
gtcgccgaggagttcgccttccgccgtctcgtcgccgtggtcggcgtgatggcggagaag
gacgcccgcggcatcctggacgcgctcgaaccggtggtgtccgagatcgtcgtcaccaag
aactcgtctccgcgcgcgatgccgctcgacgagctcaacgacatcgccatctcgatcttc
ggtgaagaccgggtcgtggccgagcccagcctggacgccgcgatcgagaccgccatcggc
ctcgtcgagcagagcgacgaccccgaagagccgctggcgggcggcggtgtgctggtcacc
ggctcggtcgtcaccgcgggtgaggcgaggaccctgttcggtaaggagccggcgtga
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