Actinoplanes sp. SE50/110: ACPL_1533
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Entry
ACPL_1533 CDS
T02044
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1 component
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase00280
Valine, leucine and isoleucine degradation
ase00640
Propanoate metabolism
ase00785
Lipoic acid metabolism
ase01100
Metabolic pathways
ase01110
Biosynthesis of secondary metabolites
ase01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ACPL_1533
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ACPL_1533
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACPL_1533
Enzymes [BR:
ase01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
ACPL_1533
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Gene cluster
GFIT
Motif
Pfam:
Transketolase_C
Transket_pyr
E1_dh
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
AEV82430
UniProt:
G8S6H3
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Position
1601431..1603704
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AA seq
757 aa
AA seq
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MIGFRRVAALAPVRDADFVTTPQSLDERFRDAVSALRPPEHPHAPGDPVRDGSTLTGARA
LEIFDAQLTSRHLDLAARWLRSFNEGFHTVASSGHEGNAAVAAALRGDDPALPHDRAAAF
YCMRAAASAPGDRTHRLEDAARDILRGVVASVRDPISGGRDKVFGNAGLHLVPVVSTPAG
HLPRAVGLAYGLSRSPDPRWPADAIVAATFGDDGVDRPGATAALHAAGWHDRAGRPIPLL
LVCEDDTPGGADPDGWAAAVLRGRPGVRYSYADGGDLAATHDAAAEAAAYVRRERRPAVL
HLGTVRLLGRPGDPDPGPDLDRDPLAGTARLLVETGLLTVDEVITRYDEIGWQVRKAAEE
VLGEPKLATVGEIVASLAPRRPLRVAHAIADAAERALGPAGANRSRVFGGRLPEQAGPMT
LAQAINATLTDALAARPGLLVFGPGTTRGGRHGVTAGLRDRGGDRVFDTPPDTTSVVGLA
LGAGLAGLLPVPELPGLGSLHSGEDQVRVEAATMSFLSSGAYRNPLVLRVPALADPYGLG
GPLDNDNSLAVLRDVPGLVVAVPARAQDAAPMLRTCLAAADLDGSVCVFLEPAALYQTRD
LYQQGDNEWLSPYPGPAQWAAEHAPIGRARIYTLGTAQDLTIVTYGGGVRMSLRVAARLA
ADGYGTRVVDLRWLSPLPVADLVRESLATGRVLIVDETRRSGGVGEGVLAALVDGSFVGS
ARRVAAADAPVPLGPAAQHVLVGEDAITQGAHALLAR
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgatcgggttccggcgggtggcagcgctcgccccggtccgcgatgctgatttcgtgacc
accccgcaaagcctcgacgagcggttccgcgatgcggtctcggccctgcggcccccggag
cacccccacgcccccggcgacccggtccgcgacggctccacgctgaccggcgcccgcgcc
ctggaaatcttcgacgcccagctcaccagccgtcacctcgacctggccgcgcgctggctg
cgcagcttcaacgagggcttccacaccgtcgcgtcgtccggccacgaggggaacgcggcg
gtcgccgccgcgctgcgcggcgacgatccggccctgccgcacgaccgggccgcggcgttc
tactgcatgcgggccgccgcgtcggcccccggcgaccggacccaccggctggaggacgcc
gcccgcgacatcctgcgcggcgtcgtcgcctcggtgcgcgacccgatcagcggcggccgc
gacaaggtcttcggcaacgccgggctgcacctggtcccggtggtctcgacgccggcgggt
cacctgccgcgcgcggtcggactggcgtacgggttgagccgctcgccggacccgcgctgg
ccggccgacgcgatcgtggccgccaccttcggcgacgacggggtcgaccggcccggcgcg
accgcggccctgcacgccgccggctggcacgaccgggccggccggcccatcccgctgctg
ctcgtctgcgaggacgacacgcccggcggcgccgacccggacggctgggccgccgcggtg
ctgcgcgggcggcccggggtgcgctactcgtacgccgacggcggcgacctggccgccacc
cacgacgccgccgccgaggcggccgcctacgtgcgccgcgaacgccgccccgccgtgctg
cacctgggcacggtccgactgctgggccgcccgggggacccggaccccggccccgacctg
gaccgcgacccgctcgccgggaccgcccggctgctcgtcgaaaccggtctgctcaccgtc
gacgaggtgatcacccggtacgacgagatcggctggcaggtccgcaaagccgccgaggag
gtgctcggcgaaccgaaactcgccaccgtcggcgagatcgtcgcctcgctcgctccacgc
cgcccactgcgggtcgcgcacgccatcgccgacgccgccgaacgcgccctcggcccggcc
ggcgcgaaccggtcccgcgtcttcggcggccggctgcccgaacaggccggcccgatgacc
ctcgcccaggcgatcaacgcgaccctcaccgacgccctcgccgcccggcccggcctgctc
gtgttcggccccggcaccacccgcggcggccggcacggagtcaccgccggactccgcgac
cgcggcggcgaccgggtcttcgacaccccgccggacaccaccagcgtggtcggtctcgcc
ctcggcgccggcctggccggcctgctcccggtgcccgaactgcccggcctgggcagcctg
cacagcggcgaggaccaggtgcgggtcgaggcggccaccatgtcgttcctgtcctccggc
gcctaccgcaacccgctggtgctgcgcgtcccggccctcgccgacccgtacggcctgggc
ggcccgctggacaacgacaactccctggccgtgctccgcgacgtgcccggcctggtcgtc
gccgtcccggcccgggcccaggacgccgccccgatgctgcgcacctgcctggccgccgcc
gacctggacggcagcgtctgcgtcttcctcgaacccgccgcgctgtatcagacgagggac
ctctatcagcaaggcgacaacgagtggctgtcgccctatccggggccggcccagtgggcc
gccgagcacgccccgatcggccgcgcccgcatctacaccctgggcacggcgcaggacctg
accatcgtcacgtacggtggcggggtgcggatgtccctgcgagtggcggcccggctggcc
gccgacgggtacggcacccgagtcgtcgatctacgctggctgagcccgctacccgtcgct
gacctggtgcgcgagtcgctggccaccggccgggtgctgatcgtcgacgagacccgccgc
tccggcggcgtcggcgaaggagtgctcgccgccctggtcgacggctccttcgtcggatcc
gcccgccgggtggccgcggctgacgccccggttccactcggaccagccgcccagcacgtg
ctggtgggagaggatgccatcacacagggtgcccacgccctgctggcgcggtaa
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