Actinobacillus suis ATCC 33415: ASU1_01295
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Entry
ASU1_01295 CDS
T03246
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ass
Actinobacillus suis ATCC 33415
Pathway
ass00260
Glycine, serine and threonine metabolism
ass00261
Monobactam biosynthesis
ass00270
Cysteine and methionine metabolism
ass00300
Lysine biosynthesis
ass01100
Metabolic pathways
ass01110
Biosynthesis of secondary metabolites
ass01120
Microbial metabolism in diverse environments
ass01230
Biosynthesis of amino acids
Module
ass_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ass_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ass_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ass00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ASU1_01295 (thrA)
00270 Cysteine and methionine metabolism
ASU1_01295 (thrA)
00300 Lysine biosynthesis
ASU1_01295 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ASU1_01295 (thrA)
Enzymes [BR:
ass01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ASU1_01295 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ASU1_01295 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
DapB_N
DUF1131
Motif
Other DBs
NCBI-ProteinID:
AIJ30536
LinkDB
All DBs
Position
complement(279612..282068)
Genome browser
AA seq
818 aa
AA seq
DB search
MRVLKFGGTSLANPERFMQAADIIEKAHLKDQAAGVLSAPAKITNHLVAIVDKAIIGESF
ESNLKEATEIFHNIINGLYAVNNNVDRDGLLALVAAELTQIQDVASEAAKTKALPDNVAA
TIHCSGEKLSIAMMQAWFEAKGYEVTRIDPVEKLLAHGSYLESSVDITESTKRVDADSIP
KKNVVLMAGFTAGNENGELVLLGRNGSDYSAACLAACLKADCCEIWTDVDGVYTCDPRLV
PEAICLESMSYQEAMELSYFGAKVIHPRTIGPLVPLNIPCLIKNTANPDAKGTLIDGNVA
TDSLKVKGITNLDNVAMFNVSGSGMQGMVGMAARVFSTMSKAGISVILITQSSSEYSISF
CVPAKFAEKATACLNAEFAQELTNGDLDPIDMIRELSIISVVGDGMRTAKGVAARFFSSL
AQANISIVAIAQGSSERSISAVVPMNKAIEAVKATHQGLFSNKKSIDVFLVGVGGVGGEL
IEQIKQQKDFLAKKDIEIRVCALANADKMLLNENGLNLDNWKSDLETATQPSDFDVLLSF
IKLHHVVNPVFVDCTAAQSVANLYTRALKEGFHVVTPNKKANTGSYQYYQELRDAARQGQ
HKFLYETNVGAGLPVIENLQNLLAAGDEVEKFEGILSGSLSFIFGKLDEGLSLSEATLIA
KEKGFTEPDPRDDLSGADVARKLLILARETGLALEFDDIEVEGVLPKGFSEGMSKEEFLK
VLPEVDSEFAQRVQAAKAEGKVLRYVGSITGDKCRVAIEAVDENHPLYKVKDGENALAFL
TRYYSPIPLLLRGYGAGTDVTAAGIFADILRTLQGGAN
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttcttaaatttggcggtacatcgcttgctaacccggaacgctttatgcaagcg
gccgatatcatcgaaaaggcacacttaaaagaccaagcggcaggtgtactttccgctccg
gctaaaatcaccaatcatcttgtcgctattgttgataaagcaattattggcgaatctttc
gaatccaatctcaaagaagcaactgaaatcttccacaacattattaatggtctctatgca
gtaaataataatgtggatcgtgatggtttattagctttagtcgcagcggaactgacccaa
attcaagatgttgcgagcgaagcggcaaaaacaaaagcattgccggataatgtagcggca
accattcactgcagtggtgaaaaattatcaatcgcaatgatgcaagcttggttcgaagcc
aaaggttatgaagttactcgcattgatcctgttgaaaaattattagctcatggtagttat
ttagaatcttcagtagatattaccgaatcgaccaagcgtgttgatgcagattcaattccg
aagaaaaacgtggtgttaatggctggttttaccgctggtaatgaaaatggcgaactcgta
ttacttggtcgtaacggttctgactattcggctgcgtgtttagctgcttgcttaaaagcg
gattgttgcgaaatttggacggatgtggacggtgtttatacctgtgaccctcgcttagtg
cctgaagcgatttgtttagagtcaatgagttaccaagaagcgatggagctttcctacttc
ggtgcgaaagtgattcacccacgtaccatcggcccgttagtcccgttaaatatcccgtgc
ttaattaaaaataccgcaaatcctgatgcaaaaggcacattaattgacggtaacgtagca
accgacagcttaaaagtgaaaggtattactaaccttgataacgttgcaatgtttaacgtt
tcgggttctggtatgcaaggtatggtcggcatggctgctcgtgtattctctaccatgtca
aaagccggtatttcagtcatcttaattacccaatcttcttctgaatacagtattagcttc
tgtgtacctgcaaaatttgccgaaaaagcgaccgcttgtttaaatgcggaatttgctcaa
gaacttacaaacggcgatttagatccgattgatatgattcgtgagctttcaattatttcg
gtagttggtgacggtatgcgtaccgcgaaaggtgttgctgctcgtttcttctcatcactt
gcgcaagcaaatatcagtattgttgcgattgcacaaggttcgtcagaacgttcaatttct
gcagtagttccgatgaataaagcaattgaagcggtaaaagcgactcaccaaggtttattt
agcaataaaaaatcaattgatgtctttctcgttggggtcggtggtgttggcggcgaatta
atcgagcaaatcaaacaacaaaaagattttttagcaaagaaggacattgaaattcgagta
tgtgcattagcaaatgccgacaaaatgttactcaatgaaaacggtttaaatttagataac
tggaaaagcgacttagaaacggcaactcaaccttcagactttgacgtattgttatcattt
atcaaattgcatcatgtagttaacccggtatttgttgactgtactgcagcacaatctgta
gcaaacctttatactcgagccttaaaagaaggtttccacgtcgtaacgccaaataaaaaa
gcgaatacaggtagctatcaatattaccaagagcttcgtgatgccgctcgccaaggtcag
cataaattcttatacgaaacaaatgtaggcgcaggtttaccggtaattgaaaacttacag
aatttgctggctgccggtgatgaagtagaaaaattcgaagggattttatccggttcactt
tcatttatcttcggaaaactagacgaaggcttaagcctttcagaagcaactttaattgcg
aaagaaaaaggtttcactgagccagatcctcgtgatgatctctcgggggcggacgtagcg
cgtaagctgttaattcttgcgcgtgaaaccggtttagcattggaattcgatgatatcgaa
gttgaaggcgtattaccgaaaggcttctctgaaggcatgagcaaggaagaattcttaaaa
gtattaccggaagtcgattcagaatttgctcaacgtgttcaagcagcaaaagcggaaggc
aaagtattacgttatgtcggctcaattaccggcgataaatgccgtgtagcaattgaagct
gtcgatgaaaaccatccgctttataaagtaaaagacggtgaaaatgcacttgcattctta
acccgttactacagtccgattcctctcttattaagaggttatggtgcaggaactgatgta
actgccgcaggtatttttgccgatattcttcgcacactccaaggaggcgcaaactaa
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