Anopheles stephensi (Asian malaria mosquito): 118505641
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Entry
118505641 CDS
T08252
Name
(RefSeq) glutamate--cysteine ligase
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
aste
Anopheles stephensi (Asian malaria mosquito)
Pathway
aste00270
Cysteine and methionine metabolism
aste00480
Glutathione metabolism
aste01100
Metabolic pathways
aste01240
Biosynthesis of cofactors
Module
aste_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
aste00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
118505641
09106 Metabolism of other amino acids
00480 Glutathione metabolism
118505641
Enzymes [BR:
aste01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
118505641
BRITE hierarchy
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
118505641
NCBI-ProteinID:
XP_035897609
LinkDB
All DBs
Position
2:82236400..82244015
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AA seq
658 aa
AA seq
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MGLLSEGSPLTWDETKALAQHVREHGIEQFINLFARLKDRQGDVLKWGDEVEYIIVRFDD
KQRAVQVSLRAQEILALLNEKEAADPQGVKSLWRPEYGAYMIEGTPGKPYGGLLAHFNVV
EANMRYRRMEVAALLPENEVVMSITSFPRLGCPGFTFPPAVPTPDDELCAARSNFFPDEA
IFPGHPRFKTLTRNIRQRRGEKVSINLPIFPDRDTVVPVPGSIPSHPDYVHMDAMGFGMG
CCCLQLTFQACNISEARTLYDQLTPMCPIMLALTAASPAYRGFLTDVDCRWNVISASVDC
RTREERGEVPLKNDRFRIYKSRYDSIDSYLSPAGEKYNDVPLVLDDALYKRLREGDIDHL
LAQHIAHLFIRDSVSLFSEKVHQNDREDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEF
RPCEAQLTDFENAAIVCFVVLLTRVILSYQLDFLIPISKVDENMQNSQKRGAVLTERFWF
KKNITAIPPGPAQQPDGDETQRKSAEQQQQQQQHNGTSDESAGSRSGADEYELMTIDQII
NGKGTFPGLVPLINSYLGSMDVDADTHCTIQQYLKLIQKRASGELMTTAAWIRQQVVSHP
EYKNDSVISEGNCYDLLRKAKDIQDGVLACPELLGNNISSKTTDNIPAAIEKHLTKRC
NT seq
1977 nt
NT seq
+upstream
nt +downstream
nt
atgggtttgctaagcgaaggcagtcctttgacgtgggacgaaacgaaggcgctggcgcag
cacgtccgcgagcacggcatcgagcagtttatcaatctgttcgcgcggctaaaagatcgc
cagggcgatgtgctgaagtggggcgacgaggtggagtacatcatcgttcgcttcgatgat
aagcagcgcgcggtgcaggtatcgctgcgtgcgcaagaaatactggccctgctgaacgaa
aaggaggcggccgatccgcaaggagtaaaatcgctttggcgtcccgagtatggcgcgtac
atgatcgagggaacgcccggcaagccgtacggggggctgctcgcccatttcaacgtcgtc
gaagcgaatatgcgctaccgccgtatggaggtggccgccctgctaccggagaacgaggta
gtcatgtcgattacaagcttcccccggttgggctgtccagggttcacgttcccaccggcc
gtcccaacgccggacgatgagctgtgtgctgcgcggtcgaactttttccccgacgaagcc
atctttcccggccacccgcggttcaagacgctcacgcgcaacattcgccaacggcgggga
gagaaggtgtcgatcaatttgcccatcttcccggaccgcgatacggtggtgccggtcccg
ggcagcataccgtcccatccggactacgtgcacatggatgcgatggggttcggtatggga
tgttgctgtttgcagcttacgttccaggcgtgtaacatcagcgaggcccgtacgctgtac
gatcagctgacgccgatgtgtcccattatgctggcgctgaccgcggccagcccggcgtac
cgcggattcctgaccgatgtggattgccggtggaacgtaatttcggcctcggtcgactgc
cgcacgcgggaggagcgtggcgaggtgccgctgaagaacgatcggttccgcatttacaaa
tcgcgttacgattcgatcgattcctacctatcaccggcaggagagaaatacaacgatgtg
cctttggtgctggacgacgcgctctacaagcggctgcgcgagggtgacatcgaccatctg
ctggcgcaacacatcgcccatctcttcatacgcgactcggtgtcgctgttcagcgagaag
gtccaccagaacgatcgcgaggacacggatcacttcgaaaacattcagtccaccaactgg
caaacgatgcggttcaagccaccgccccccaactcgtcgatcgggtggcgcgtcgagttc
cggccgtgcgaggcacagctgaccgacttcgagaacgcagccatcgtgtgcttcgtggtg
ctgctgacgcgcgtcatcctttcgtaccagctcgatttcctcattcccatcagcaaggtg
gacgaaaacatgcaaaactcgcagaagcgtggcgccgtgctgaccgagcgcttttggttc
aagaaaaacattaccgccattccgcccggtccggcacagcagccggacggtgatgagacg
caacggaaatcggccgaacagcagcagcagcagcagcagcataatggcaccagcgatgaa
tcggccggttcccgttccggtgcggacgagtacgagctgatgacgatcgatcagattatc
aacggcaaagggacattcccgggcttggtgccgctgattaacagttatctcggttcgatg
gatgtcgatgcggacacacactgcacgattcagcagtacctgaagctgatacagaaacga
gcgtccggtgagctgatgacgactgcggcctggatacgtcagcaggtcgtgtcacatccc
gaatacaaaaatgattccgtcatcagcgagggcaactgctacgatctgctgcgaaaggcg
aaggacatccaggacggtgtgctggcgtgcccggaactgctcggcaacaacatcagctcc
aaaacgacggacaacattccggctgcgatcgagaagcatctcaccaagcgctgttag
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