Aquincola tertiaricarbonis: MW290_18540
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Entry
MW290_18540 CDS
T08158
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ater
Aquincola tertiaricarbonis
Pathway
ater00790
Folate biosynthesis
ater01100
Metabolic pathways
ater01240
Biosynthesis of cofactors
Module
ater_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ater00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MW290_18540 (folC)
Enzymes [BR:
ater01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MW290_18540 (folC)
6.3.2.17 tetrahydrofolate synthase
MW290_18540 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
URI11857
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Position
2:946503..947801
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AA seq
432 aa
AA seq
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MTTPPRSLADWLAHCERLHPKNIDMTLDRVRAVAQRLGIRFSVPVITVAGTNGKGSTCAM
LEAIAQCAGYRVGLYIKPHLVHFEERCRINGRMADEATLLPHFEAVEAARGDTTLSYFEF
TMLAILRTFMHAPLDLVILEVGLGGRLDAVNIIDTDCAVITSIDLDHTEWLGPTREDIGR
EKAHIMRPGKPAIVSDPVPPQTVIDHAQAIGADLWLAGRDFRHSGDRQQWQWAGRQRRFS
ALAYPALRGANQLLNAAGALAVFEALYQQLPITAQAVRQGLALVDLPGRFQIVPGQPTLV
LDVAHNAQSVAALALNLDQMGFFPRTHAVFGAMRDKDLPALLAKLSPLVDHWHLCNLDTA
RAATADELAAAVQAMPRQQPVTVQTHADPAAALAAAVAAADPADRIVVFGSFYTVGGVLK
DGLPRLSAKHTG
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
ctgacgacgcccccccgctcgctcgccgactggctggcccactgcgagcgcctgcacccc
aagaacatcgacatgacgctggaccgcgtgcgcgcggtcgcccagcgcctgggcatccgt
ttcagcgtgcccgtgatcaccgtggccggcaccaacggcaagggctccacctgcgccatg
ctggaagcgattgcccagtgcgccggctaccgcgtggggctgtacatcaagccgcacctg
gtgcacttcgaggagcgctgccgcatcaatggccgcatggccgacgaggccacgctgctg
ccgcacttcgaggccgtggaagccgcccgcggcgacaccacgctgagctacttcgagttc
accatgctggccatcctgcgcaccttcatgcatgcgccgctggacctggtgatcctggaa
gtgggcctgggcggccggctggacgcggtgaacatcatcgacaccgattgcgcggtgatc
accagcatcgacctcgaccacaccgagtggctgggcccgacgcgtgaagacatcggccgc
gagaaggcgcacatcatgcggccgggcaagccggccatcgtcagcgacccggtgccgccg
cagacggtgatcgaccatgcgcaggccatcggcgccgacctctggctggcgggccgcgat
ttccgccacagcggcgaccgccagcagtggcaatgggccggccgccagcggcgcttcagc
gcgctggcctacccggcgctgcgtggcgccaaccagctgctcaatgccgccggtgcgctg
gcggtgttcgaggcgctttaccagcagctgcccatcaccgcgcaggcggtgcgccagggg
ctggcgctggtggatctgccgggccgtttccagatcgtgcccggccagccgacgctggtg
ctggacgtggcgcacaacgcgcaatcggtggcggcgctggcgctcaacctcgaccagatg
ggcttcttcccgcgcacgcatgcggtgttcggtgccatgcgcgacaaggacctgcccgcg
ctgctggccaagctctcgccgctggtggaccactggcacctgtgcaacctggacaccgcc
cgcgccgccacggccgacgagctggccgccgcggtgcaggccatgccgcgccagcagccg
gtgacggtgcagacgcacgccgatccggcggccgcactggcggctgcggtggctgccgca
gacccggctgatagaatcgtggtcttcggttctttctacaccgtaggcggcgtgctgaag
gacggtttgccgcggctgagcgccaagcacacgggttga
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