Actinomyces urogenitalis: R3I39_10305
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Entry
R3I39_10305 CDS
T09523
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase family protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
auo
Actinomyces urogenitalis
Pathway
auo00790
Folate biosynthesis
auo01100
Metabolic pathways
auo01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
auo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
R3I39_10305
Enzymes [BR:
auo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
R3I39_10305
6.3.2.17 tetrahydrofolate synthase
R3I39_10305
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
PPDK_N
DUF6158
Beta-APP
Motif
Other DBs
NCBI-ProteinID:
WOO95048
LinkDB
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Position
complement(2408988..2410928)
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AA seq
646 aa
AA seq
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MSTTHDDVTGQHPGAAFGIPEGAEGEEVVDAVFGDARPSEGLEALRAELAAQAEGRIAGI
EGIDPALMPYLEAAQEEDSLVGPDGSLTLAQVREAGISQAEREAAQEEEDLQALRELVAH
NMLGSTGSGDLDQLDALLAEVDEDDSDDWDQWDQWEPVLPQADDPTDLGEELASEIEQHQ
ADLRAAAHGVEVSARMRQVEAEILSRAPEHKVQPSLERVEAVLDIIGHPERTYTVVHITG
TNGKTSTARMTERLLAATGMRTGRFTSPHLATIRERISLDGEPISEEGFIAAWEDVAPYV
AMVDERSQASGGPRMSFFEVLTVMAFAAFADYPVDVAVIEVGMGGTWDSTNVVDSAVEVI
TPIGRDHQAWLGDTIEQIASNKAGIIKDGATLITSTQPRQAQEVIAEAAAAHAVVWRREL
GTQEDPDATDAGVLQVVDRTLAVGGQMVTLKTAAATYEDVFIPLHGQYQAHNALLALAAA
EAVFAGRALPARVVQDGFAAATSPGRLEVLRSSPTVIVDAGHNPHGVSALVPAVQEAFGF
QHLVAVVGAMADKDVEGILSVLEPATDAVVVVPMDSPRAMEVEDLAAVAREVYGEDRVIV
AEDLGSGVEQAVALSEGFDAPMTASGVLIVGSVVLAAEARALFHRA
NT seq
1941 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccacgcacgacgacgtcaccggccagcacccgggagccgccttcggtatccct
gagggcgccgagggcgaggaggtcgtcgacgccgtcttcggcgatgcccggcccagtgag
ggcctggaggccctgcgcgcggagctcgccgcccaggccgaggggcgcatcgccggcatc
gagggcattgatcccgcgctgatgccctacctggaggccgcgcaggaggaggactcgctg
gtaggcccggacgggtccctgaccctggcgcaggtgcgtgaggccggtatctcgcaggcc
gagcgcgaggcggcacaggaggaagaggacctgcaggccctgcgtgagctggtggctcac
aacatgctgggttcgacgggctccggcgacctggaccagctcgacgccctgctcgctgag
gtcgacgaggacgacagcgacgactgggaccagtgggaccagtgggagccggtcctgccg
caggcggatgatcccaccgacctgggtgaggagctggccagcgagatcgagcagcaccag
gccgatctgcgcgcagccgcccacggcgtcgaggtctcggcgcgtatgcgccaggttgag
gccgagatcctctctcgcgcccctgagcacaaggtccagccctccctggagcgtgtcgag
gcggtcctcgacatcatcggccaccccgaacgcacctacacggtcgtccacatcaccggc
accaacggcaagacctcgacggcgcggatgaccgagcggctgctggcggccacggggatg
cgcaccggccggttcaccagcccgcacctggccaccatccgcgagcgcatcagcctggac
ggtgagcccatcagcgaggagggcttcatcgccgcctgggaggacgtggccccctacgtc
gccatggtggacgagcgctcgcaggcgagcggcggcccgaggatgtccttcttcgaggtc
ctgaccgtcatggccttcgcggccttcgccgactacccggtggacgtcgcggtgatcgag
gtcggcatgggcggtacctgggactcgaccaacgtcgtcgactccgccgtcgaggtcatc
acgcccatcggccgtgaccaccaggcctggctgggggacacgatcgagcagatcgcctcc
aacaaggccggcatcatcaaggatggcgccaccctcatcacctccacccagcctcgccag
gcccaggaggtcatcgctgaggccgctgcggcccacgccgtggtgtggcgccgcgagctg
gggacgcaggaagacccggacgccacggacgccggagtgctgcaggtggtggaccgcacg
ctggctgtggggggacagatggtcactctcaagacggcggcagctacctacgaggacgtc
ttcatccccctgcacgggcagtaccaggctcataacgccctgctcgccctggccgcggcg
gaggcggtcttcgccgggcgggctctgccggcccgggtggtccaggacgggttcgctgcg
gcgacctcgcccgggcgcctggaggtgctgcgctcctcgccgaccgtgatcgtggacgcc
gggcacaacccgcacggcgtgtccgccttggtcccggccgtgcaggaggccttcggcttc
cagcacctggtggccgtggtcggggcgatggcggacaaggacgtcgaggggatcctctcc
gtcctggagccggcgacggacgccgtggtcgttgtccccatggactctccgcgggccatg
gaggtcgaggacctggccgccgtggcgcgggaggtctacggcgaggaccgtgtcatcgtg
gccgaggacctgggttccggcgtcgagcaggccgtggcgctgtccgagggctttgacgct
ccgatgacggcctcaggcgtgctcatcgtcgggtccgtcgtcctggcggctgaggccagg
gcgctgttccaccgcgcctga
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