Brevibacillus brevis: BBR47_18250
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Entry
BBR47_18250 CDS
T00879
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
bbe
Brevibacillus brevis
Pathway
bbe00790
Folate biosynthesis
bbe01100
Metabolic pathways
bbe01240
Biosynthesis of cofactors
Module
bbe_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
bbe00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BBR47_18250 (folC)
Enzymes [BR:
bbe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BBR47_18250 (folC)
6.3.2.17 tetrahydrofolate synthase
BBR47_18250 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
BAH42802
UniProt:
C0ZAJ3
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All DBs
Position
1919520..1920893
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AA seq
457 aa
AA seq
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MHAEEGFVEYTQALDWLHGLLRFGQRPGLERMQWVLEQVGHPERRIPFIHVAGTNGKGST
CAFLTQMLMEAGYSVGTFTSPYLVDFRERIRYNGSMIAEEDLLQLVNEVKVWVQRCEQET
EYGSPTEFEVITLIAILYFSRVARPAVVVWETGLGGRLDSTNVVLPLVSVITNIGMDHTQ
VLGESLEDIAREKAGIIKPGVPVVTGEVRPELLAVFEERARQMKSTLYHIGEHFQAEQVE
EQLGDQQFGYKSIHRRAEASYRLTMNGIHQTTNAAVALMTIDVLRNYFSFLLEEEEISRG
LQQTRWPGRLEVISPRPMVILDGAHNQEGMEALVSSLDRLLPDGVQLHLLFSGLADKPLA
KMAESLAPVKSKMKKLHVTTFDFPRAAEANSLQESFLAGGWEQEFLDAVPDWRAFLLSWM
REKQLAKADDWLVVCGSLYFIAQVRAFFPTIVEEAGE
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgcatgcagaagaagggtttgtagaatacacccaagcgctcgactggctgcatggactg
ctcaggttcggtcaacggccggggcttgagagaatgcagtgggttttggagcaggtagga
catcctgagcggagaatcccgtttattcatgtggctggcaccaatggaaaaggttcaacc
tgcgcattcctgacgcaaatgctgatggaagccggatatagtgtaggtacatttacctcc
ccctatttggtggatttccgtgaacgcatccgttacaacggcagcatgattgcggaagaa
gatctattgcagctggtgaatgaagttaaggtgtgggtgcaacgatgcgaacaagaaaca
gagtatggttcccctaccgaatttgaagtgattacgctgatcgccattctttatttttca
agagtggcgagaccagcggtagtcgtttgggaaacaggactaggcgggcgattggattcg
acgaacgtcgtccttccgcttgtttcagtcatcacgaatatcggcatggaccatacacaa
gtgctgggagaaagcttggaagatattgcccgggaaaaagcggggattatcaagccgggt
gttcctgtagtcacaggtgaggttaggccggaacttctcgcggtttttgaggagcgcgcg
agacaaatgaagagtacgctatatcatataggtgaacatttccaggcagagcaggtagag
gagcagctgggtgatcaacagtttggttacaaaagcattcaccgtcgtgcggaagcatcc
taccgtcttaccatgaatggcattcaccaaacaaccaatgcagccgttgctttaatgact
atcgatgtcctgcgaaattacttctctttcttgctggaggaagaagaaatatctcgtggt
ttgcaacaaacgcgttggcctggtcgtctagaagtcatctctccaagaccaatggttatc
ttggatggggcacacaatcaggaaggaatggaggcgcttgtaagcagtctggatcggttg
ttgccggacggagtacagttgcatttgctcttttctggattggcagataagccgctcgcc
aaaatggcagagtcgctcgcaccagttaagtcaaaaatgaaaaagctgcatgtgacaacc
tttgacttcccgcgtgcagccgaagccaatagcttacaagagtcgtttttagccggaggc
tgggagcaagagtttctcgatgcagtcccagactggcgggcgtttctcctttcttggatg
cgggagaagcaattagcgaaggcggatgactggctggtcgtctgcggttcgctctacttc
atcgcccaagtacgcgcattctttcccactatagtagaagaggcaggtgaatag
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