KEGG   Bison bison bison (American bison): 104994637
Entry
104994637         CDS       T08726                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01523  Antifolate resistance
bbis04010  MAPK signaling pathway
bbis04014  Ras signaling pathway
bbis04024  cAMP signaling pathway
bbis04062  Chemokine signaling pathway
bbis04064  NF-kappa B signaling pathway
bbis04066  HIF-1 signaling pathway
bbis04071  Sphingolipid signaling pathway
bbis04151  PI3K-Akt signaling pathway
bbis04210  Apoptosis
bbis04211  Longevity regulating pathway
bbis04218  Cellular senescence
bbis04380  Osteoclast differentiation
bbis04613  Neutrophil extracellular trap formation
bbis04620  Toll-like receptor signaling pathway
bbis04621  NOD-like receptor signaling pathway
bbis04622  RIG-I-like receptor signaling pathway
bbis04623  Cytosolic DNA-sensing pathway
bbis04625  C-type lectin receptor signaling pathway
bbis04657  IL-17 signaling pathway
bbis04658  Th1 and Th2 cell differentiation
bbis04659  Th17 cell differentiation
bbis04660  T cell receptor signaling pathway
bbis04662  B cell receptor signaling pathway
bbis04668  TNF signaling pathway
bbis04722  Neurotrophin signaling pathway
bbis04917  Prolactin signaling pathway
bbis04920  Adipocytokine signaling pathway
bbis04926  Relaxin signaling pathway
bbis04931  Insulin resistance
bbis04932  Non-alcoholic fatty liver disease
bbis04933  AGE-RAGE signaling pathway in diabetic complications
bbis04936  Alcoholic liver disease
bbis05010  Alzheimer disease
bbis05022  Pathways of neurodegeneration - multiple diseases
bbis05030  Cocaine addiction
bbis05132  Salmonella infection
bbis05133  Pertussis
bbis05134  Legionellosis
bbis05135  Yersinia infection
bbis05140  Leishmaniasis
bbis05142  Chagas disease
bbis05145  Toxoplasmosis
bbis05146  Amoebiasis
bbis05152  Tuberculosis
bbis05160  Hepatitis C
bbis05161  Hepatitis B
bbis05162  Measles
bbis05163  Human cytomegalovirus infection
bbis05164  Influenza A
bbis05165  Human papillomavirus infection
bbis05166  Human T-cell leukemia virus 1 infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05168  Herpes simplex virus 1 infection
bbis05169  Epstein-Barr virus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05171  Coronavirus disease - COVID-19
bbis05200  Pathways in cancer
bbis05202  Transcriptional misregulation in cancer
bbis05203  Viral carcinogenesis
bbis05206  MicroRNAs in cancer
bbis05207  Chemical carcinogenesis - receptor activation
bbis05208  Chemical carcinogenesis - reactive oxygen species
bbis05212  Pancreatic cancer
bbis05215  Prostate cancer
bbis05220  Chronic myeloid leukemia
bbis05221  Acute myeloid leukemia
bbis05222  Small cell lung cancer
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05321  Inflammatory bowel disease
bbis05415  Diabetic cardiomyopathy
bbis05417  Lipid and atherosclerosis
bbis05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104994637 (NFKB1)
   04014 Ras signaling pathway
    104994637 (NFKB1)
   04064 NF-kappa B signaling pathway
    104994637 (NFKB1)
   04668 TNF signaling pathway
    104994637 (NFKB1)
   04066 HIF-1 signaling pathway
    104994637 (NFKB1)
   04071 Sphingolipid signaling pathway
    104994637 (NFKB1)
   04024 cAMP signaling pathway
    104994637 (NFKB1)
   04151 PI3K-Akt signaling pathway
    104994637 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    104994637 (NFKB1)
   04218 Cellular senescence
    104994637 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    104994637 (NFKB1)
   04620 Toll-like receptor signaling pathway
    104994637 (NFKB1)
   04621 NOD-like receptor signaling pathway
    104994637 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    104994637 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    104994637 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    104994637 (NFKB1)
   04660 T cell receptor signaling pathway
    104994637 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    104994637 (NFKB1)
   04659 Th17 cell differentiation
    104994637 (NFKB1)
   04657 IL-17 signaling pathway
    104994637 (NFKB1)
   04662 B cell receptor signaling pathway
    104994637 (NFKB1)
   04062 Chemokine signaling pathway
    104994637 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    104994637 (NFKB1)
   04917 Prolactin signaling pathway
    104994637 (NFKB1)
   04926 Relaxin signaling pathway
    104994637 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104994637 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104994637 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    104994637 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104994637 (NFKB1)
   05202 Transcriptional misregulation in cancer
    104994637 (NFKB1)
   05206 MicroRNAs in cancer
    104994637 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    104994637 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    104994637 (NFKB1)
   05203 Viral carcinogenesis
    104994637 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104994637 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104994637 (NFKB1)
   05221 Acute myeloid leukemia
    104994637 (NFKB1)
   05220 Chronic myeloid leukemia
    104994637 (NFKB1)
   05215 Prostate cancer
    104994637 (NFKB1)
   05222 Small cell lung cancer
    104994637 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104994637 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    104994637 (NFKB1)
   05161 Hepatitis B
    104994637 (NFKB1)
   05160 Hepatitis C
    104994637 (NFKB1)
   05171 Coronavirus disease - COVID-19
    104994637 (NFKB1)
   05164 Influenza A
    104994637 (NFKB1)
   05162 Measles
    104994637 (NFKB1)
   05168 Herpes simplex virus 1 infection
    104994637 (NFKB1)
   05163 Human cytomegalovirus infection
    104994637 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104994637 (NFKB1)
   05169 Epstein-Barr virus infection
    104994637 (NFKB1)
   05165 Human papillomavirus infection
    104994637 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104994637 (NFKB1)
   05135 Yersinia infection
    104994637 (NFKB1)
   05133 Pertussis
    104994637 (NFKB1)
   05134 Legionellosis
    104994637 (NFKB1)
   05152 Tuberculosis
    104994637 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    104994637 (NFKB1)
   05145 Toxoplasmosis
    104994637 (NFKB1)
   05140 Leishmaniasis
    104994637 (NFKB1)
   05142 Chagas disease
    104994637 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    104994637 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104994637 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    104994637 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    104994637 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104994637 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    104994637 (NFKB1)
   05415 Diabetic cardiomyopathy
    104994637 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    104994637 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    104994637 (NFKB1)
   04931 Insulin resistance
    104994637 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    104994637 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    104994637 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bbis03000]
    104994637 (NFKB1)
Transcription factors [BR:bbis03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    104994637 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 104994637
NCBI-ProteinID: XP_010846583
Ensembl: ENSBBBG00000023074
UniProt: A0A6P3HVI3
LinkDB
Position
Unknown
AA seq 974 aa
MHSSRMAEDDPYLGGHEQMFHLDPLNHTMFSPELFQPEMPLPTADGPYLQILEQPKQRGF
RFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVG
KHCEDGVCTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTDACIRGYNPGLLVHPDL
AYLQAEGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVV
SDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWE
GFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKD
KEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGAGGGGAGSTGPGYGFPHYGFPTYG
GITFHTGTTKSNAGMKHGTIDTPSKNDPESCGKSDDREVVNLSEQVTETTEQDGGSCKGG
TAANLTCSVGVKEENRSFQDNLFLEKAMQLAKQHANALFDYAVTGDVKMLLAVQRHLTAV
QDENGDSVLHLAIIHLHNQLVRDLLEVTSGLISDEIINMRNDLYQTPLHLAVITRQEAVV
EDLLRAGADLSLLDRLGNSVLHLAAKEGHDKILGILLKHKKAAQLIDHPNGEGLNAIHVA
MMSNSLPCLLLLMAAGADVNAQERKSGRTALHLAVEHDNVSLAGCLLLEGDAHVDSTTYD
GTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWDEDGEDEGVVPGTTPLDM
ASSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQK
LGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIDVIQAAFCTTDTS
PAKTTSQAHSLPFAPASTRPQIDELRDDSICDSGVETSFRKLSFTESLTSGTSLLTLNKV
PHDYGQEGPIEGKI
NT seq 2925 nt   +upstreamnt  +downstreamnt
atgcacagctccagaatggcagaagacgacccgtatttgggagggcatgaacaaatgttt
catctggatcctctgaatcatacaatgtttagtccagaattatttcaaccggagatgcca
ctaccaacagcagatggcccataccttcaaatattagagcaacctaaacagagaggattt
cgtttccgttacgtgtgtgaaggcccctcccatggagggctccccggtgcgtctagtgaa
aagaacaagaagtcctaccctcaggtcaaaatctgcaactatgtgggacctgcaaaggtt
attgttcagttggtcacaaatggaaaaaacatccacctgcatgcacacagcctggtggga
aaacactgtgaggatggcgtctgcactgtgacagccgggcccaaggacatggtggtcggc
tttgcaaacctgggtattcttcatgtgacaaagaaaaaagtattcgaaacactggaagca
cgaatgacagatgcctgtatacggggctataatcccggacttttggtgcatcctgatctt
gcctatttgcaggcagaaggcggaggagaccggcagctcacagatcgggaaaaagaaatc
atccgccaggcagctcttcagcagacgaaggagatggacctcagcgtggtacggctcatg
tttacagctttccttccagacagcaccggcagcttcacgaggcgtctggaacctgtggtg
tcggacgccatctatgacagcaaagcccccaatgcatctaacttgaaaatagtaagaatg
gacaggacagctggatgtgtaactggaggggaagagatttatcttctctgtgacaaggtt
cagaaagatgacatccagattcgattttatgaagaggaggaaaacggtggaatttgggaa
ggatttggagatttttcccccacagatgttcatagacaatttgccattgtcttcaaaact
ccaaagtataaagatgtcaacattacaaaaccagcctccgtgttcgtccagcttcggagg
aaatctgatttggaaactagcgaaccaaaacctttcctctactatcctgaaatcaaagat
aaagaggaagtgcaaaggaaacgacagaagctcatgcccaatttctcggacagtttcggc
ggtggcagcggtgctggagccggaggcgggggcatgtttggcagcggtgctggaggtggg
ggtgctggaagtaccggcccagggtatggcttcccccactatggattccccacgtatggc
ggaattaccttccatactggaaccactaaatctaatgctgggatgaagcatggaaccata
gacaccccatctaaaaatgaccctgaaagttgtggcaagagtgatgacagagaggttgta
aatctctctgagcaagtaacagaaaccacagaacaagatggaggatcctgcaaggggggc
actgcagctaacctgacgtgctccgtaggagtaaaggaagagaaccgcagcttccaggat
aacctctttctggagaaggctatgcagctggccaagcagcacgccaacgccctctttgac
tacgcagtgacaggagacgtgaagatgctgctggccgtccagcgccatctcactgccgtg
caggatgagaacggggacagtgtcttacacttggcaatcatccaccttcataatcagctt
gtgagagatctgctggaagtcacatctggcttgatttctgatgaaattatcaacatgaga
aatgatctctaccagacacccctgcacttggcagtgatcaccagacaggaagctgtggtg
gaggacttgctgagggctggcgctgacctgagcctcctggaccgcttgggtaactctgtt
ttgcacctcgctgccaaagaaggacatgataaaattctcggtattttactcaagcacaaa
aaggcagcacaacttattgaccaccccaacggggaaggtctgaatgccatccatgtagcc
atgatgagcaacagcttgccgtgtctgctgctgctgatggccgcgggggctgacgttaac
gcccaggagcggaagtcggggcgcacggcgctgcacctggccgtggagcacgacaacgtc
tccttggctggttgcctgctcctggagggtgatgcccacgtggacagcaccacttatgac
gggactacacccctgcacatagcggccggcagagggtccaccaggctggcagctcttctc
aaagcagcaggagcagatcccctggtggagaacttcgagcctctgtacgacctggatgac
tcctgggatgaggatggagaggatgaaggggtcgtaccgggaaccactcctctggacatg
gccagcagctggcaggtatttgacatattaaatgggaaaccctatgagccagagtttacg
tctgatgatttgctggcacaaggagacatgaaacagctgactgaagatgcaaagctgcag
ctgtacaagttgctagaaattcctgatccagacaaaaactgggctactctggcacagaaa
ttaggtctggggatactgaacaacgccttccggctgagtcccgctccttccaagaccctc
atggacaactacgaggtctccgggggcaccataaaggagctggtggaggccctgagacag
atgggctacactgaggccattgacgtgatccaggcagccttctgcaccacagacaccagc
ccggccaagaccacctcccaagcccactcgctgccattcgcccccgcctccacaaggcca
caaatagacgagctccgggacgacagcatctgtgacagcggtgtagagacctccttccgc
aaactcagcttcactgagtctctgaccagcggcacctccttgctaactcttaacaaagtg
ccccacgactacgggcaggaaggacctatagaaggcaaaatttag

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