KEGG T08726: 104994894

Bison bison bison (American bison): 104994894

Entry

104994894         CDS       T08726

Symbol

HSD17B8

Name

(RefSeq) estradiol 17-beta-dehydrogenase 8 isoform X1

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

bbis Bison bison bison (American bison)

Pathway

bbis00061

Fatty acid biosynthesis

bbis00140

Steroid hormone biosynthesis

bbis01100

Metabolic pathways

bbis01212

Fatty acid metabolism

Module

bbis_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:bbis00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    104994894 (HSD17B8)
   00140 Steroid hormone biosynthesis
    104994894 (HSD17B8)
Enzymes [BR:bbis01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     104994894 (HSD17B8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     104994894 (HSD17B8)

SSDB

Motif

Pfam:

adh_short adh_short_C2 KR Epimerase RmlD_sub_bind ALOG_dom

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

Unknown

AA seq 271 aa
MASPLRLRSALALVTGAGGGIGRAISVRLAAEGAAGAACDLDGAAARETVQLLGGPGTEE
GAPRGAHAAFQADVSEAGAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEDNWDK
VIAVNLKGIFLVTQAAAQALVSSGCPGSIINISSIIGKVRLSWEEVGNMGQTNYAASKAG
VIGLTQSAARELGRHGIRCNSVLPGFIRTPMTQKVPQKVLDKMWQMSSHSWHLKTVDTSQ
GYQWKSLEVFSCNCLKDPGLCSPPTALLASC

NT seq 816 nt +upstreamnt +downstreamnt
atggcgtctccgctccgattgcgctccgcgctggccctggttacaggtgcgggcggcggc
attggccgcgccatcagcgtgcgcctcgccgctgagggggccgccggagccgcttgcgac
ctggacggggcagcagcgcgggagacggtgcagctgctgggagggccggggaccgaggag
ggggcgccccgcggagcccacgccgccttccaggctgatgtgtctgaggcaggggccgct
aggcgcctgctggagcaagtgcaggcctgcttttctcgcccgccgtctgtcgttgtgtcg
tgtgcgggcatcaccagagatgaatttctactccacatgtctgaggacaactgggacaaa
gtcatagctgtcaacctcaagggcatctttctagtcactcaggctgcagcccaagccctc
gtgtccagcggctgtcctggctccatcatcaacatcagtagcatcataggcaaggtcagg
ctgagctgggaggaggtggggaacatgggacagacaaactatgcagcatccaaggctgga
gtgattgggctgacccagtctgcagcccgggaacttggacgacacgggatccgctgtaac
agtgtcctcccaggattcattagaacacccatgacccagaaagtgccacagaaagtgctg
gacaagatgtggcagatgtcgtcgcattcttggcatctgaagacagtggatacatcacag
gggtatcagtggaagtcactggaggtcttttcatgtaactgcctcaaggaccctggactc
tgctcaccccccactgctctgctggcctcctgctga

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