KEGG   Bison bison bison (American bison): 104998318
Entry
104998318         CDS       T08726                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01521  EGFR tyrosine kinase inhibitor resistance
bbis01522  Endocrine resistance
bbis04010  MAPK signaling pathway
bbis04014  Ras signaling pathway
bbis04015  Rap1 signaling pathway
bbis04066  HIF-1 signaling pathway
bbis04068  FoxO signaling pathway
bbis04114  Oocyte meiosis
bbis04115  p53 signaling pathway
bbis04150  mTOR signaling pathway
bbis04151  PI3K-Akt signaling pathway
bbis04152  AMPK signaling pathway
bbis04211  Longevity regulating pathway
bbis04213  Longevity regulating pathway - multiple species
bbis04510  Focal adhesion
bbis04550  Signaling pathways regulating pluripotency of stem cells
bbis04730  Long-term depression
bbis04750  Inflammatory mediator regulation of TRP channels
bbis04913  Ovarian steroidogenesis
bbis04914  Progesterone-mediated oocyte maturation
bbis04935  Growth hormone synthesis, secretion and action
bbis04960  Aldosterone-regulated sodium reabsorption
bbis05200  Pathways in cancer
bbis05202  Transcriptional misregulation in cancer
bbis05205  Proteoglycans in cancer
bbis05214  Glioma
bbis05215  Prostate cancer
bbis05218  Melanoma
bbis05224  Breast cancer
bbis05410  Hypertrophic cardiomyopathy
bbis05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104998318 (IGF1)
   04014 Ras signaling pathway
    104998318 (IGF1)
   04015 Rap1 signaling pathway
    104998318 (IGF1)
   04066 HIF-1 signaling pathway
    104998318 (IGF1)
   04068 FoxO signaling pathway
    104998318 (IGF1)
   04151 PI3K-Akt signaling pathway
    104998318 (IGF1)
   04152 AMPK signaling pathway
    104998318 (IGF1)
   04150 mTOR signaling pathway
    104998318 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104998318 (IGF1)
   04115 p53 signaling pathway
    104998318 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104998318 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    104998318 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    104998318 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    104998318 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    104998318 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    104998318 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    104998318 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    104998318 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    104998318 (IGF1)
   04213 Longevity regulating pathway - multiple species
    104998318 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104998318 (IGF1)
   05202 Transcriptional misregulation in cancer
    104998318 (IGF1)
   05205 Proteoglycans in cancer
    104998318 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    104998318 (IGF1)
   05218 Melanoma
    104998318 (IGF1)
   05215 Prostate cancer
    104998318 (IGF1)
   05224 Breast cancer
    104998318 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    104998318 (IGF1)
   05414 Dilated cardiomyopathy
    104998318 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104998318 (IGF1)
   01522 Endocrine resistance
    104998318 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbis04052]
    104998318 (IGF1)
Cytokines and neuropeptides [BR:bbis04052]
 Cytokines
  Growth factors (RTK binding)
   104998318 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 104998318
NCBI-ProteinID: XP_010851726
Ensembl: ENSBBBG00000015932
UniProt: A0A6P3IB16
LinkDB
Position
Unknown
AA seq 188 aa
MGKISSLPTQLFKCCFCDFLKQVKMPITSSSHLFYLALCLLAFTSSATAGPETLCGAELV
DALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSAR
SVRAQRHTDMPKAQKYQPPSTNKKMKSQRRRKGGPKKRPGGEQKEGTEASQQMQGKMKEQ
RRETGARN
NT seq 567 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aagcaggtgaagatgcccatcacatcctcctcgcatctcttctatctggccctgtgcttg
ctcgccttcaccagctctgccacggcgggacccgagaccctctgcggggctgagttggtg
gatgctctccagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtac
ggctcgagcagtcggagggcgccccagacaggaatcgtggatgagtgctgcttccggagc
tgtgatctgaggaggctggagatgtactgcgcgcctctcaagcccgccaagtcggcccgc
tcagtccgtgcccagcgccacaccgacatgcccaaggctcagaagtatcagcccccatct
accaacaagaaaatgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccagga
ggggaacagaaggaggggacggaagcaagtcagcagatgcaagggaagatgaaagagcag
aggagagagactggagctagaaactga

DBGET integrated database retrieval system