Bison bison bison (American bison): 105003971 Help Entry 105003971         CDS       T08726                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism bbis  Bison bison bison (American bison) Pathway bbis00220   Arginine biosynthesis bbis00330   Arginine and proline metabolism bbis01100   Metabolic pathways bbis04020   Calcium signaling pathway bbis04066   HIF-1 signaling pathway bbis04146   Peroxisome bbis04371   Apelin signaling pathway bbis04926   Relaxin signaling pathway bbis05010   Alzheimer disease bbis05014   Amyotrophic lateral sclerosis bbis05022   Pathways of neurodegeneration - multiple diseases bbis05133   Pertussis bbis05140   Leishmaniasis bbis05142   Chagas disease bbis05145   Toxoplasmosis bbis05146   Amoebiasis bbis05152   Tuberculosis bbis05200   Pathways in cancer bbis05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     105003971 (NOS2)    00330 Arginine and proline metabolism     105003971 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105003971 (NOS2)    04066 HIF-1 signaling pathway     105003971 (NOS2)    04020 Calcium signaling pathway     105003971 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     105003971 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     105003971 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105003971 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     105003971 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     105003971 (NOS2)    05152 Tuberculosis     105003971 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     105003971 (NOS2)    05145 Toxoplasmosis     105003971 (NOS2)    05140 Leishmaniasis     105003971 (NOS2)    05142 Chagas disease     105003971 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     105003971 (NOS2)    05014 Amyotrophic lateral sclerosis     105003971 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     105003971 (NOS2) Enzymes [BR:bbis01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      105003971 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  105003971 NCBI-ProteinID:  XP_010859745 Ensembl:  ENSBBBG00000018223 UniProt:  A0A6P3J8K7 LinkDB All DBs Position Unknown AA seq 1155 aa AA seqDB search MREGLGAACEAARPRLCRLLRRILRPQPACRLRRASPVTQDDPKRHSPGKHGNESPQPLT GTVKTSPESLSKLDAPPSACPRHVRIKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIMN PKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQL TGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNIR SAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGR FDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVGG LEFPGCPFNGWYMGTEVGVRDFCDVQRYNILEEVGRRMGLETHKVASLWKDRAVVEINVA VLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEML NYVLSPFYYYQVEAWKTHVWQDERRRPQRREIRFKVLVKAVFFASVLMHKAMASRVRATI LFATETGRSETLAQDLGALFSCAFNPKVLCMDQYQLSHLEEEQLLLVVTSTFGNGDSPGN GEKLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGDE LSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPQHYRLVQDSEPLDLN KALSSMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQP ALVQGILERVVDGPAPHQPVRLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQL LLRKLAQLATEEAEKQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQLP ILKPRYYSISSSRDLTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCFV RSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPEE DHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLYV CGDVRMARDVARTLKQLMATALSLNEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDGA AGLPSDPRAPGAHRS NT seq 3468 nt NT seq  +upstreamnt  +downstreamnt atgcgcgaggggctgggcgccgcgtgcgaggccgcccggccccggctctgccggctcctc cgcaggatcctccggccgcagcccgcctgccgcctccgccgagccagtccagtgacacag gatgaccccaaacgtcacagcccgggcaagcacgggaatgagtctccccagcccctcacg gggacagtaaagacgtctccagaatccctgagcaagctggacgcgcccccgtcagcctgt ccacggcatgtgaggatcaaaaactggggcagcggagtgactttccaagacacgcttcac cagaaggccaaaggggatctctcttgcaagtccaagtcttgcctggcatccatcatgaac cccaaaagtttgaccataggaccccgggacaagccaacccccccagacgagcttctacct caagctatcgaatttgtcaaccagtattacggctccttcaaagaggcaaaaatagaggaa catctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctaccagctg acgggagatgagctcatcttcgccaccaagcaggcctggcgcaatgccccccgctgcatc ggaaggatccagtggtcgaacctgcaggtctttgacgcccggagctgttccacggcccag gaaatgttcgaacacatctgcagacacgtgcgttatgccaccaacaacggcaacatcagg tcggccatcactgtgttcccccagcggagtgatgggaagcatgacttccgggtctggaac gcccagctcatccgctatgccggctaccagatgccggatggcagcatcagaggggaccct gccaacgtggagttcacacagctgtgcatcgacctgggctggaagcccaagtacggccgc ttcgacgtgttgcctctagtcctgcaggctgacggccgtgacccagagctcttcgaaatc ccccctgaccttgtgctcgaggtgcccatggaacatcccaggtacgaatggttccgggag ctggagctcaagtggtacgccctgccagccgtggccaacatgctgcttgaggtgggcggc ctcgagttcccagggtgccccttcaacgggtggtacatgggcacagaagttggagtccgg gacttctgcgacgtccagcgatacaacatcctggaggaagtgggcagaaggatgggcctg gaaacgcacaaggtggcctcactctggaaggaccgggctgtcgttgagatcaacgtcgct gtgctccacagtttccagaagcagaacgtgaccatcatggaccaccactccgctgcagag tccttcatgaagtacatgcagaatgagtaccgctcccgagggggctgcccagctgactgg atttggctggtccccccgatctctggaagcatcacccccgtgttccaccaggagatgtta aattacgtcctgtcccctttctactactaccaggtggaggcctggaaaacccacgtctgg caggacgagaggcggagaccccagagaagagagattcgattcaaagtcttggtcaaagct gtgttcttcgcctcggtgctgatgcataaggccatggcatcccgggtcagagccacgatc ctctttgcaacagagacggggagatcggaaacgctggcccaggacctgggggctttgttc agctgtgccttcaaccccaaggttctctgcatggatcagtaccagctgagccatctggag gaggagcagctgctgctggtggtgaccagcacttttggcaacggagactcccctggcaac ggagagaaactgaagaagtccctcttgatgctgaaagaactcaccaacacattccggtac gccgtgtttggccttggctccagcatgtaccctcagttctgcgcttttgctcatgacatc gaccagaagttgtcccagctgggggcttctcagcttgccccaaccggggaaggagacgaa cttagcgggcaggaggaggcctttcgcagctgggccgtgcaaaccttcaaggcagcctgt gagacattcgatgtcagcggcaagcaccacattgagatccccaagctctacacttccaat gtgacctgggacccgcagcactacaggctcgtgcaggactcagagcctctggacctcaac aaagccctgagcagtatgcacgccaagcatgtgttcaccatgaggctcaaatcgcagcag aatctgcagagtccgaaatccagccgcaccaccctcctggtggaactctcctgtgagggc agccaagctccaagctacctgccgggagagcacctcggagttttcccatgcaaccagccg gccctggttcaaggcatccttgagcgagtggtggatggccctgccccgcaccagcctgtg cgcctggagaccctctgtgagaatggcagctactgggtcaaggataagcggctgccacct tgctcactcagccaggctctcacctatttcctggacatcaccaccccgccaacccagctg ctgctccgaaagctggcccagctggccacagaagaggctgagaagcagaggctggagacc ctatgccagccctcagattacaacaagtggaagttcaccaacagccccacatttctggag gtgctggaggagttcccgtccctgcgggtgtctgccagcttcctgctctcccagctccct attctgaagccccggtactactccatcagctcctccagggacctcacacccacggagatc cacctcactgtggccgtgctcacgtaccgcacccgagatggccaaggtcccctgcaccat ggcgtctgcagcacgtggctcagcagcttgaagccccaagacccggtgccctgctttgtg cgaagtgccagcggcttccagcttcccgaggaccgctcccgtccttgcatcctcattggg cccggcacgggcatcgcccccttccgcagtttctggcagcagcggctccatgaggctgag cacaaagggctccagggcggccgcatgaccctggttttcgggtgccgccgcccagaagag gaccacctctactgggaggagatgctggagatggcccgcaagggggtgctgcacgaggtg cacacggcctattcccgcctgcctgaccagcccaaggtctatgttcaagacatcctgcgg cagcggctggcgggcgaggtgcttcgcgtgctgcacgaggagcaaggccacctctatgtc tgtggggatgtgcgcatggcccgggacgtggcccgcaccctgaagcagctgatggctact gcgctgagcctgaatgaggaacaggtggaggactatttcttccagctcaagaaccagaag cgctatcatgaagacatctttggtgctgtatttccctatgaggtgaaaaaggatggggca gcagggctgcccagtgatcccagagctccaggcgcccacagaagttaa

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