Brettanomyces bruxellensis: BRETT_004196
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Entry
BRETT_004196 CDS
T07183
Symbol
LEU1
Name
(RefSeq) 3-isopropylmalate dehydratase
KO
K01702
3-isopropylmalate dehydratase [EC:
4.2.1.33
]
Organism
bbrx
Brettanomyces bruxellensis
Pathway
bbrx00290
Valine, leucine and isoleucine biosynthesis
bbrx01100
Metabolic pathways
bbrx01110
Biosynthesis of secondary metabolites
bbrx01210
2-Oxocarboxylic acid metabolism
bbrx01230
Biosynthesis of amino acids
Module
bbrx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bbrx00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BRETT_004196 (LEU1)
Enzymes [BR:
bbrx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
BRETT_004196 (LEU1)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Aconitase_C
Motif
Other DBs
NCBI-GeneID:
64576119
NCBI-ProteinID:
XP_041135468
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Position
5:complement(389316..391649)
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AA seq
777 aa
AA seq
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MSSEAAKKQPRTLYDKVFDAHVVHKDPSGSYLLYIDRHLVHEVTSPQAFEGLRNAGRTVR
RPDCTLATVDHNIPTDSRKNFKSISTFIKQGDSRLQVETLEQNVKRYNIPFFGMTDTRQG
IVHIVGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTIIQARSKNM
RIRIEGDLEPGITSKDLVLHVIHVIGTAGGTGCVIEFAGKAIRNLSMEARMSICNMSIEA
GARAGMIQPDERTFEYVKGRPLAPRGAEWEKALAYWKTLYSDEGAKFDREVVIQAKDIIP
TVTWGNSPQDALPITGKVPDPATIEDPSAKSSCIAALEYMGLKPNTPLKDIYVDKIFIGS
CTNSRIEDLREAARVARGHHIAKNIKRALVVPGSGAIKKEAEEEGLDKIFKDAGFEWREA
GCSMCLGMNPDILDPYERCASTSNRNFRGRQGALSRTHLMSPAMAAATAILGHFSDIRDF
DYIDSVDKPKLPLSSAEELERLQIEKRELDEDLAEPAAPHDGVDDSAKVTEEISSEQSKD
GKSSGMEKFVTLTSVAAPLTKENIDTDAIIPKQFLKTIKRTGLRKGLFYESRFAKDANGK
MVPTDFVLNVDPYTHAKILVVTGKNFGCGSSREHAPWALKDFGIRSIIAPSFGDIFYNNS
FKNGLLPIRLPQEVIEKKLYPLAVAKKELTVDLPNQQIKGPDGSVLVDNFDVEDFRKHCL
LNGLDDIGITLQKVKFIDDYEKIRKSKFSFLEGGSKRLISPVGEVNKSIHGAKESEW
NT seq
2334 nt
NT seq
+upstream
nt +downstream
nt
atgtcttccgaagctgctaaaaaacaacctagaacattatacgataaggttttcgatgcg
cacgttgtgcacaaggacccatcaggatcatatcttctatacattgaccgtcacttggtt
catgaggttacttcacctcaggcatttgaaggtttaagaaatgcaggccgtactgtgaga
agaccagactgcaccttggcaactgttgaccacaatattcctactgactcaagaaagaat
ttcaagagcatctccacgttcatcaagcagggagactctagattgcaggtggaaactttg
gagcagaatgtcaaaaggtacaacattccattctttggaatgaccgataccagacagggt
attgttcatattgttggtcctgagcaaggattcactcttccaggtaccactgttgtttgt
ggtgactctcacacttccacacatggtgcctttggtgcattggcatttggtattggtacc
tcagaggtcgagcatgttttggccacacaaaccattattcaggctagatcaaagaacatg
agaattcggattgaaggtgatctcgagccaggtatcacctctaaggatcttgttttgcac
gtcatccacgtgattggtaccgccggtggtacgggttgcgttattgaatttgctggtaag
gccatcagaaacctttcgatggaggctagaatgtctatttgtaacatgtctatagaggcc
ggtgcaagagctggtatgattcagcctgatgaaagaaccttcgaatacgttaagggaaga
ccattggctccaagaggtgctgaatgggagaaggctcttgcatactggaaaacgctttat
tccgacgagggagccaagtttgatcgtgaggttgtgattcaggccaaggatatcattcca
actgtcacctggggtaactctccacaggatgcattgcctatcacaggaaaggttccagat
ccagctacgatcgaagatccttccgcaaagagtagttgcattgccgctttggaatacatg
ggcttgaagccaaacactcctttgaaggacatctacgtggataagattttcattggttcg
tgcacaaactcccgtattgaggatcttcgtgaagcagcaagggtggctcgtggacaccat
attgctaagaacattaaaagagcattggttgttccaggttccggtgcaattaagaaggag
gctgaggaagaaggactcgacaaaattttcaaggatgctggatttgaatggagagaggcc
ggatgttctatgtgcttaggtatgaatccggatatcttggacccatacgagagatgcgca
tccacctcaaacaggaacttccgtggaagacaaggtgctctttcaagaacgcacttgatg
tcaccggctatggctgctgcaactgcaatcttgggtcatttctctgacattagagacttt
gactatattgacagcgtcgataagccaaaacttcctcttagtagcgctgaggaattggag
aggcttcaaattgaaaagcgtgagcttgatgaggacttggcagagccagctgctcctcac
gatggagtggatgatagcgcaaaggttacggaagaaatttcttcagaacagtcaaaggat
ggaaagtcatctggaatggagaagtttgttacattaacgtctgtggctgctccattgaca
aaggagaacatcgatactgatgctatcattccaaagcagttcttgaagactattaagaga
accggtctacggaaaggtctcttctacgaatcgagatttgccaaagatgcaaacggaaaa
atggttcctacggactttgttcttaatgtggatccatacactcatgctaagattttggtg
gtaacaggtaaaaactttggatgtggatcatccagagagcacgctccttgggcattgaaa
gactttggtatcagatccatcattgctccttcatttggtgatatcttctacaacaactcc
ttcaagaatggtttgttgccaatcagacttcctcaggaggtcatcgagaaaaagctttat
ccattggctgttgccaagaaggagcttactgtggatcttccaaatcaacaaatcaaaggc
ccagatggatctgttttggttgacaactttgacgtcgaagacttcagaaagcattgcttg
ttgaatggtctcgatgatattggaattacattacagaaggtcaagttcatcgacgattat
gagaagattagaaagagtaagttctcattcttggagggtggctctaagagattaatttct
ccggttggggaggtcaacaagtcgatacatggggctaaagaatctgaatggtga
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