Bubalus bubalis (water buffalo): 102402213
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Entry
102402213 CDS
T05912
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub04217
Necroptosis
bbub04380
Osteoclast differentiation
bbub04620
Toll-like receptor signaling pathway
bbub04621
NOD-like receptor signaling pathway
bbub04630
JAK-STAT signaling pathway
bbub04658
Th1 and Th2 cell differentiation
bbub04659
Th17 cell differentiation
bbub05145
Toxoplasmosis
bbub05160
Hepatitis C
bbub05161
Hepatitis B
bbub05162
Measles
bbub05164
Influenza A
bbub05165
Human papillomavirus infection
bbub05167
Kaposi sarcoma-associated herpesvirus infection
bbub05168
Herpes simplex virus 1 infection
bbub05169
Epstein-Barr virus infection
bbub05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102402213 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102402213 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102402213 (TYK2)
04621 NOD-like receptor signaling pathway
102402213 (TYK2)
04658 Th1 and Th2 cell differentiation
102402213 (TYK2)
04659 Th17 cell differentiation
102402213 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
102402213 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
102402213 (TYK2)
05160 Hepatitis C
102402213 (TYK2)
05171 Coronavirus disease - COVID-19
102402213 (TYK2)
05164 Influenza A
102402213 (TYK2)
05162 Measles
102402213 (TYK2)
05168 Herpes simplex virus 1 infection
102402213 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102402213 (TYK2)
05169 Epstein-Barr virus infection
102402213 (TYK2)
05165 Human papillomavirus infection
102402213 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102402213 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102402213 (TYK2)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102402213 (TYK2)
Protein kinases [BR:
bbub01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102402213 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
102402213
NCBI-ProteinID:
XP_006068401
EnsemblRapid:
ENSBBUG00015008184
LinkDB
All DBs
Position
9:96284490..96312587
Genome browser
AA seq
1187 aa
AA seq
DB search
MPLCQWRATTRGRQPNGDGAQPMATREGLKVLLHWAGPSGGEPWVTFTEPTLTAEDVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGAETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMALLHLCHLALRNGVPLEKVAKKTSFKDCIPRSFRRQIRQHNALTRLRQRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELQSQANGEPCYIRDGGQA
PPDPGSESAAGPPTHEVLVSGTEGIRWRLVPAEGPADGGAGGGSRMPDADPSGKKMKAKE
VDSEPVDRPRESPWSYFCDFQDITHMVLKERHVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTTDSNHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLKPEAGLYLIHWSTSHL
HRLILTVAQRDQLQAPGTKGLRLRKFPIELQAGTVMLEGWGRSFPSVRDLRAALQDCSLR
AGDDCFSLCRCCLPRPGEISNLIVTRGPQASTRPLNLSHLSFYRVRQEDITQLSHLGQGT
RTNVYEGLLRVGGRGPEEDKADGEEPPTPAGDHGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVFVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLTVAQQLAS
ALSYLEDKSLVHGNVCGRNILLARLGLVEGTSPFIKLSDPGVGLSALSREERVERIPWTA
PECLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPE
LATLTSQCLTYEPAQRPSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIDILRTLYHKHIV
KYKGCCEDQGEKSIQLVMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHTQHYV
HRDLAARNVLLDNNRLVKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYF
ASDVWSFGVLMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPERC
PSEIYCLMKDCWKAEASFRPTFQNLVPILRSYHEKYQGQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggagggccaccaccaggggcaggcagcccaacggggacggagct
cagcccatggccaccagagaaggcctgaaagtgcttctgcactgggctggccccagtggt
ggggagccctgggtcaccttcactgagcccacactgaccgcggaggatgtctgcatccac
atcgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacatcctggatacctccagggactccagcctg
acgctgtacttccgcatgaggttttatttccgaaactggcatggcacgaatcctcaggag
ccagctgtgtaccgctgtgggcccccaggggccgagacttcctcagaacaggcagagcag
ggggtgcaactcctggaccctgcctcctttgagtacctctttgagcagggcaagcatgaa
tttgtaaatgacgtggcatcactatgggagctgtccagtgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccacctcgctctccgcaacggt
gtcccccttgaaaaggtggccaagaagaccagcttcaaggattgcatcccacgctccttc
cggcggcagatccggcagcacaacgctctgacacggctgcgccaacggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctgtcccagcaggtcgtcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcccgtgtgccac
ctggagctgcagtcccaagccaacggggagccctgctacatccgggacggtgggcaggcc
cctcccgaccccgggtctgagtctgctgctggaccccccacccacgaggtgctggtgtca
ggcacggaaggcatccggtggcggctggtaccggcggaggggcctgctgatggtggtgct
ggtggtggcagcaggatgcctgatgctgacccatctgggaagaaaatgaaggccaaggag
gtggacagcgagccagtggacaggcctcgagagagcccctggtcctacttctgtgacttc
caggacatcacccacatggtgctgaaggaacgccacgtcagcatccattgtcaggacaac
aagtgcctggagctgaccctgccttcccgggctgcggccctatccttggtgtcgctggtg
gatggctacttccgcctgaccaccgactcaaaccactacctgtgccacgaggtggctcct
ccacggctggtgatgagtatccaggatggtatccatggccccctgctggagccatttgtg
ctggccaagctgaagcccgaggctggcctctaccttatccactggagcaccagccacctc
caccgcctcatcctcacggtggcccagcgcgaccagctgcaggctccgggcactaagggc
ttgcgcctgcggaagttccctatcgagctccaggccgggacagtcatgctggagggctgg
ggccggtctttccccagcgtgcgggacctgcgggccgccctgcaggactgctcgctgcgg
gccggcgacgactgcttttccctgtgtcgctgctgcctgccccggcctggagagatctcc
aacctcatcgtcacgcgggggcctcaggccagcaccagaccgctcaacctcagtcatctc
agcttctaccgagtccgccaggaagacatcacccagctgtcccacttgggccagggcaca
aggaccaacgtgtatgagggcctcttgcgagtggggggcagaggccccgaggaggacaag
gcagatggcgaggaaccccccacgcccgctggggaccatgggcaggagctgcgcgtggta
ctcaaggtgctagaccccagtcaccacgacatcgccctggccttctacgagacagccagc
ctcatgagccaggtctcccacgtgcacctggccttcgtgcacggtgtcttcgtgcacggc
tccgagaacatcatggtgaccgagtacgtggagcacgggcccctggacgtatggctgcgg
cgggagaggggccgcgtgcccctggcctggaagttgacagtggcccagcagctggccagc
gccctcagttacctggaagacaaaagcctggttcatggcaacgtgtgtggccggaacatc
ctgctggcacggctggggctggtggagggcaccagccccttcatcaagctgagtgacccc
ggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatcccctggacagcc
cctgagtgcctgtctggtggagccaacagcctgagcaccgcagccgacaagtggggcttt
ggtgccaccctcctggagatctgcttcgacggcgaggcccccctgcagggccgcagtccc
tctgagaaagagcgcttctaccagaagcagcacaaactgcctgagccctcgtgcccagag
ctggccacactcaccagccagtgcctgacctacgagccagcccagcggccatccttccgc
accatcctgcgtgacttcactcagctacagccccagaatctcgctgatgtcttgtctgtg
agcccggattcactggcttcagatcccacggttttccacaagcgatacttgaaaaagatc
cgggatctgggtgagggtcacttcggaaaggtcagcctgtattgctacgaccccaccaac
gacggcactggtgagatggtagccgtgaaggccctcaaggcaggctgcggtccccagctc
cggacgggctggaggcgagaaatcgacatcctacgcacgctctaccacaagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcgatacagctggtcatggaatac
atgcccctgggcagcctccgagactacttgccccggcacaatgtcgggctggtccagctg
ctgctcttctccctgcagatctgcgagggtatggcctacctgcacacacagcactacgtg
catcgagacctggccgcgcgcaacgtgctgctagacaacaacaggctggtcaagatcggg
gacttcggcctcaccaaggccgtgcccgaaggccacgagtattactgcgtgcgcgaggat
ggggacagtcctgtgttctggtatgccccggagtgcctgaaggagtgtaagttctacttt
gcatcagacgtctggtcctttggggtcctcatgtatgagctgctgacctactgtgactcc
agccagagccctccctcgaaattcattgagctcataggcctcacccaagggcagatgact
gtgctgaggctcacagagctgctggaacgaggggagaggctgccacaaccagagagatgc
ccctctgagatctattgcctcatgaaggactgctggaaggcagaggcctcattccgcccg
accttccagaacctcgtacccatcctcagatcataccacgagaaataccaaggccaggcc
ccctcggtgttcagtgtctgctga
DBGET
integrated database retrieval system
