Bubalus bubalis (water buffalo): 102409665
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Entry
102409665 CDS
T05912
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X3
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01522
Endocrine resistance
bbub04010
MAPK signaling pathway
bbub04015
Rap1 signaling pathway
bbub04068
FoxO signaling pathway
bbub04071
Sphingolipid signaling pathway
bbub04114
Oocyte meiosis
bbub04148
Efferocytosis
bbub04218
Cellular senescence
bbub04261
Adrenergic signaling in cardiomyocytes
bbub04370
VEGF signaling pathway
bbub04380
Osteoclast differentiation
bbub04550
Signaling pathways regulating pluripotency of stem cells
bbub04611
Platelet activation
bbub04613
Neutrophil extracellular trap formation
bbub04620
Toll-like receptor signaling pathway
bbub04621
NOD-like receptor signaling pathway
bbub04622
RIG-I-like receptor signaling pathway
bbub04625
C-type lectin receptor signaling pathway
bbub04657
IL-17 signaling pathway
bbub04658
Th1 and Th2 cell differentiation
bbub04659
Th17 cell differentiation
bbub04660
T cell receptor signaling pathway
bbub04664
Fc epsilon RI signaling pathway
bbub04668
TNF signaling pathway
bbub04670
Leukocyte transendothelial migration
bbub04714
Thermogenesis
bbub04722
Neurotrophin signaling pathway
bbub04723
Retrograde endocannabinoid signaling
bbub04728
Dopaminergic synapse
bbub04750
Inflammatory mediator regulation of TRP channels
bbub04912
GnRH signaling pathway
bbub04914
Progesterone-mediated oocyte maturation
bbub04917
Prolactin signaling pathway
bbub04926
Relaxin signaling pathway
bbub04932
Non-alcoholic fatty liver disease
bbub04933
AGE-RAGE signaling pathway in diabetic complications
bbub04935
Growth hormone synthesis, secretion and action
bbub04936
Alcoholic liver disease
bbub05014
Amyotrophic lateral sclerosis
bbub05020
Prion disease
bbub05022
Pathways of neurodegeneration - multiple diseases
bbub05132
Salmonella infection
bbub05133
Pertussis
bbub05135
Yersinia infection
bbub05140
Leishmaniasis
bbub05142
Chagas disease
bbub05145
Toxoplasmosis
bbub05152
Tuberculosis
bbub05161
Hepatitis B
bbub05163
Human cytomegalovirus infection
bbub05167
Kaposi sarcoma-associated herpesvirus infection
bbub05169
Epstein-Barr virus infection
bbub05170
Human immunodeficiency virus 1 infection
bbub05171
Coronavirus disease - COVID-19
bbub05205
Proteoglycans in cancer
bbub05208
Chemical carcinogenesis - reactive oxygen species
bbub05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bbub05415
Diabetic cardiomyopathy
bbub05417
Lipid and atherosclerosis
bbub05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102409665 (MAPK12)
04015 Rap1 signaling pathway
102409665 (MAPK12)
04370 VEGF signaling pathway
102409665 (MAPK12)
04668 TNF signaling pathway
102409665 (MAPK12)
04068 FoxO signaling pathway
102409665 (MAPK12)
04071 Sphingolipid signaling pathway
102409665 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102409665 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
102409665 (MAPK12)
04218 Cellular senescence
102409665 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102409665 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102409665 (MAPK12)
04613 Neutrophil extracellular trap formation
102409665 (MAPK12)
04620 Toll-like receptor signaling pathway
102409665 (MAPK12)
04621 NOD-like receptor signaling pathway
102409665 (MAPK12)
04622 RIG-I-like receptor signaling pathway
102409665 (MAPK12)
04625 C-type lectin receptor signaling pathway
102409665 (MAPK12)
04660 T cell receptor signaling pathway
102409665 (MAPK12)
04658 Th1 and Th2 cell differentiation
102409665 (MAPK12)
04659 Th17 cell differentiation
102409665 (MAPK12)
04657 IL-17 signaling pathway
102409665 (MAPK12)
04664 Fc epsilon RI signaling pathway
102409665 (MAPK12)
04670 Leukocyte transendothelial migration
102409665 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
102409665 (MAPK12)
04914 Progesterone-mediated oocyte maturation
102409665 (MAPK12)
04917 Prolactin signaling pathway
102409665 (MAPK12)
04926 Relaxin signaling pathway
102409665 (MAPK12)
04935 Growth hormone synthesis, secretion and action
102409665 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
102409665 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
102409665 (MAPK12)
04723 Retrograde endocannabinoid signaling
102409665 (MAPK12)
04722 Neurotrophin signaling pathway
102409665 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102409665 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
102409665 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
102409665 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102409665 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
102409665 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102409665 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102409665 (MAPK12)
05161 Hepatitis B
102409665 (MAPK12)
05171 Coronavirus disease - COVID-19
102409665 (MAPK12)
05163 Human cytomegalovirus infection
102409665 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
102409665 (MAPK12)
05169 Epstein-Barr virus infection
102409665 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
102409665 (MAPK12)
05135 Yersinia infection
102409665 (MAPK12)
05133 Pertussis
102409665 (MAPK12)
05152 Tuberculosis
102409665 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102409665 (MAPK12)
05140 Leishmaniasis
102409665 (MAPK12)
05142 Chagas disease
102409665 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102409665 (MAPK12)
05020 Prion disease
102409665 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
102409665 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102409665 (MAPK12)
05418 Fluid shear stress and atherosclerosis
102409665 (MAPK12)
05415 Diabetic cardiomyopathy
102409665 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102409665 (MAPK12)
04932 Non-alcoholic fatty liver disease
102409665 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
102409665 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102409665 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbub01001
]
102409665 (MAPK12)
Enzymes [BR:
bbub01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102409665 (MAPK12)
Protein kinases [BR:
bbub01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102409665 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kdo
APH
Kinase-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102409665
NCBI-ProteinID:
XP_006066392
EnsemblRapid:
ENSBBUG00015014546
LinkDB
All DBs
Position
4:442862..450877
Genome browser
AA seq
367 aa
AA seq
DB search
MSSPSPARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQTLKGLKYIHAAGVIHRDLKPSNLAVNEDCELKILDFGLARQADT
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSMGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAERRV
TAAEALAHPYFESLHDTEDEPQAEKYDESFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAK
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgtcgcccgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcagcccgtgggctcgggcgcctacggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccatcaagaagctgtaccgg
ccctttcagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcacgcccgatgagacgctggat
gacttcacggacttctacctggtgatgccgttcatgggcaccgacctgggaaagctcatg
aagcacgagaagctgagcgaggaccgggtgcagttcctcgtctaccagacactcaagggg
ctgaagtacatccacgctgccggcgtcatccacagggacttgaagcccagcaacttggct
gtgaacgaggactgtgagctgaagatcctggacttcggcctggcccggcaggcagacacc
gagatgactggctacgtggtgacccggtggtaccgcgcacccgaggtcatcttgaactgg
atgcactacacgcagacagtggacatctggtccatgggctgcatcatggccgagatgatc
acggggaagacgctcttcaaaggcagcgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctccagcggagtttgtgcagaggctgcaaagtgacgaggccaagaac
tacatgaagggcctccctgagctggagaagaaggattttgcctccgtcctgaccaacgcg
agccccctggccgtgagcctcctggagaaaatgctggtgctggacgcggagcggcgggtg
acggcggccgaggcgctggcccacccctactttgagtcgctgcacgacacggaggacgag
ccccaggccgagaagtatgatgagtcctttgacgatgtggaccgcacgctggatgagtgg
aagcgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gtctccaaggagacagccttgtga
DBGET
integrated database retrieval system