Bubalus bubalis (water buffalo): 102416487
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Entry
102416487 CDS
T05912
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub00010
Glycolysis / Gluconeogenesis
bbub00020
Citrate cycle (TCA cycle)
bbub00620
Pyruvate metabolism
bbub00785
Lipoic acid metabolism
bbub01100
Metabolic pathways
bbub01200
Carbon metabolism
bbub01210
2-Oxocarboxylic acid metabolism
bbub04066
HIF-1 signaling pathway
bbub04922
Glucagon signaling pathway
bbub05230
Central carbon metabolism in cancer
bbub05415
Diabetic cardiomyopathy
Module
bbub_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102416487 (PDHA1)
00020 Citrate cycle (TCA cycle)
102416487 (PDHA1)
00620 Pyruvate metabolism
102416487 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102416487 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102416487 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102416487 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102416487 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102416487 (PDHA1)
Enzymes [BR:
bbub01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102416487 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102416487
NCBI-ProteinID:
XP_006045899
EnsemblRapid:
ENSBBUG00015024535
LinkDB
All DBs
Position
X:18142093..18162774
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRHFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCNDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctctcgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatctcgtcattttgcaaatgatgctacttttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcactacagtgcttaccagagaagat
gggctcaaatactacaggatgatgcagactgttcgccgaatggagttaaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtaggcctggaggccggcatcaaccccacagaccatctgatcacagcgtaccgggct
catggctttacctttactcgtggactctctgtccgggagattcttgcagagcttacagga
cgaagaggtggttgtgctaaaggaaaaggaggatcgatgcatatgtatgccaagaatttc
tacggaggcaatggcatcgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagacgaggtctgtttgactttgtacggcgatggtgctgctaat
cagggtcagatattcgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggaaagagcagcagccagcact
gattactacaagagaggcgactttattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggccacaaaatttgcagctgcctattgtagatctggaaaggggcctata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtgagt
taccgtacccgagaagagattcaggaagttagaagtaagagtgaccctatcatgctcctc
aaggacaggatggtgaacagcaatctcgccagtgttgaagaactaaaggaaattgatgtg
gaagtgagaaaagaaattgaggatgctgctcagtttgctactgctgatcctgaaccacct
ttggaagaacttggctatcacatttactgcaacgatccaccttttgaagtccggggtgca
aaccagtggatcaagtttaagtccatcagttaa
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