Bufo bufo (common toad): 121009488
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Entry
121009488 CDS
T07950
Symbol
HSD17B8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
bbuf
Bufo bufo (common toad)
Pathway
bbuf00061
Fatty acid biosynthesis
bbuf00140
Steroid hormone biosynthesis
bbuf01100
Metabolic pathways
bbuf01212
Fatty acid metabolism
Module
bbuf_M00873
Fatty acid biosynthesis in mitochondria, animals
bbuf_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bbuf00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
121009488 (HSD17B8)
00140 Steroid hormone biosynthesis
121009488 (HSD17B8)
Enzymes [BR:
bbuf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
121009488 (HSD17B8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
121009488 (HSD17B8)
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GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
GDP_Man_Dehyd
Polysacc_synt_2
TrkA_N
3Beta_HSD
Sacchrp_dh_NADP
RmlD_sub_bind
F420_oxidored
MgtC_SapB_C
CbiA
3HCDH_N
NAD_binding_7
2-Hacid_dh_C
Motif
Other DBs
NCBI-GeneID:
121009488
NCBI-ProteinID:
XP_040298573
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All DBs
Position
8:complement(209627992..209636339)
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AA seq
255 aa
AA seq
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MAAPMRLKSTLALVTGGGGGIGRAVCQRLSQEGASVVVVDCNIDSANETLRSLSRGVPGQ
DHVALTADVSRSESVRALMEQIQSHFSAPPRVAVNNAGITRDEFLLRLSEESFQSVLDVN
LKGPFLITQAVAQSIVTSGQNGGSIINMGSIVGKVGNLGQASYAASKAGVEGLTKTAAKE
LAKFGIRCNTVLPGFIATPMTDKVPQKVLDKIAGLIPMGRLGQPEDVADVCAFLASDDSR
YITGASIEVTGGLYL
NT seq
768 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgcccatgaggttgaagtccacgctggctctagtgacaggtgggggcggcggg
atcggtcgcgctgtctgtcagcgcctgtcgcaggaaggggcttcagtcgtcgtcgttgat
tgtaacattgactcggctaatgaaaccctccggagcctgtcacgtggggtcccagggcag
gaccatgtggccctcactgccgacgtctccaggtctgagagtgtcagggctctcatggag
cagatacagtctcacttctctgctcctcctcgtgtggccgtcaacaatgcgggaatcacc
agggacgagtttctgcttcgtctgtcagaggaatccttccagtccgtgctggatgtcaac
ctcaagggtccgttcctcatcacacaggccgtggcccaatccattgtaaccagcgggcag
aacggtggctccatcatcaacatgggcagcatcgtgggaaaggtaggtaatctcggccag
gccagctacgctgcctctaaagccggagtggaaggtcttacgaagactgcagctaaagaa
ctggccaagtttggtatccgctgtaacacagtattacctggatttatagccaccccaatg
actgataaagtcccacagaaagtgctggacaagattgcgggtctgattccgatggggagg
ctcggccagcctgaagatgtcgccgatgtttgcgctttcctggcttcagatgacagcaga
tatatcacaggggcgagtatagaagtgacaggtggcctgtatttatga
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