Burkholderia cenocepacia HI2424: Bcen2424_1243
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Entry
Bcen2424_1243 CDS
T00415
Name
(GenBank) branched-chain alpha-keto acid dehydrogenase E1 component
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bch
Burkholderia cenocepacia HI2424
Pathway
bch00280
Valine, leucine and isoleucine degradation
bch00640
Propanoate metabolism
bch00785
Lipoic acid metabolism
bch01100
Metabolic pathways
bch01110
Biosynthesis of secondary metabolites
bch01210
2-Oxocarboxylic acid metabolism
Module
bch_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bch00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Bcen2424_1243
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Bcen2424_1243
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Bcen2424_1243
Enzymes [BR:
bch01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Bcen2424_1243
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ABK07995
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Position
1:1373295..1374527
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AA seq
410 aa
AA seq
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MSLSEPLRLHVPEPTGRPGCKTDFSYLHLSPAGAVRRPPIDVAAADTADLARSLVRVLDD
NGKAVGPWAPDLDDARLIAGLRAMLKTRIFDARMMIAQRQKKISFYMLSLGEEAIGTAHA
MALRDGDMCFPTYRQQSILIARDVPLERMICQLMSNEGDPLKGRQLPVMYSDREAGFFSI
SGNLATQFIQAVGWAMASAIKGDTKIASAWIGDGATAEADFHTALTFAHVYRAPVVLNVV
NNQWAISTFQAIAGGEGTTFAGRGVGCGIASLRVDGNDFLAIYAASSWAAERARRNLGPT
LIEWVTYRAGAHSTSDDPTKYRPSDDWSHFPLGDPIERFKRHLIVKGIWSDSAHDALTAE
LEAEVIAAQKEAEKYGTLADDRIPSPASMFDDVYKELPAHLRRQRQELGA
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagcctgtcagagccattgcgtctgcatgtgccggagcccaccgggcgcccgggctgc
aagacggacttttcctatctgcatctatcgccggccggcgccgtgcgccgcccaccgatc
gacgttgccgcggcggacaccgccgatctcgcccgcagcctcgtgcgcgtgctcgacgac
aacggcaaggccgtcggcccgtgggcccccgatctcgacgatgcgcggctgatcgccggg
ctgcgcgcgatgctcaagacccgcattttcgacgcgcgcatgatgatcgcgcagcgtcag
aagaaaatctccttctacatgttgagcctcggcgaagaggcgatcggcaccgcgcacgcg
atggcgctgcgcgacggcgacatgtgctttccgacctaccggcagcagagcatcctgatc
gcgcgcgacgtgccgctcgagcggatgatctgccagctgatgtcgaacgaaggcgatccg
ctgaagggccgccagctcccggtgatgtactcggaccgcgaagccggcttcttctccatt
tccggcaacctcgcgacgcagttcatccaggcggtcggctgggcgatggcgtcggcgatc
aagggcgacacgaagatcgcatccgcatggatcggcgacggcgcgacggccgaagccgat
ttccataccgcgctcacgttcgcgcatgtgtaccgcgcgccggtcgtgctgaacgtggtc
aacaaccagtgggcgatctcgacgttccaggcgatcgcgggcggcgagggcacgaccttc
gcggggcgcggcgtcggttgcgggatcgcgtcgctgcgcgtcgacggcaacgacttcctc
gcgatctatgcggcgtcgagctgggcggccgagcgtgcgcgccgcaatctcggcccgacg
ctgatcgagtgggtgacctaccgcgcgggcgcgcattcgacgtcggacgatccgaccaag
taccggccgagcgacgactggtcccatttcccgctgggcgatccgatcgagcgcttcaag
cgccacctgatcgtgaagggcatctggtcggacagcgcgcacgacgcgttgacggccgag
ctcgaggccgaggtgatcgccgcgcagaaggaagcggagaagtacgggacgctggccgac
gaccggattccgtcgccggcctcgatgttcgacgacgtgtacaaggagctgcccgcgcac
ctgcgccgtcagcgccaggaactgggagcgtga
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