Bacillus halotolerans: DIC78_08345
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Entry
DIC78_08345 CDS
T06619
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
bht
Bacillus halotolerans
Pathway
bht00860
Porphyrin metabolism
bht01100
Metabolic pathways
bht01110
Biosynthesis of secondary metabolites
bht01120
Microbial metabolism in diverse environments
bht01240
Biosynthesis of cofactors
Module
bht_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
bht_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
bht00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
DIC78_08345 (cobA)
Enzymes [BR:
bht01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
DIC78_08345 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
DIC78_08345 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
HEM4
RRM_7
Motif
Other DBs
NCBI-ProteinID:
AZV49040
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Position
1658548..1659999
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AA seq
483 aa
AA seq
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MIMKNGIVYFVGAGPGDPGLITIKGKQALEEADVILYDRLANPKLLEYASPDCQFIYCGK
LPDRHFMKQAEINALLIEKASEGLTVVRLKGGDPSVFGRVGEEADALHQHGIRYEMVPGI
TSGIAAPLYAGIPVTHRDFASSFAMITAHDKSLKGTPNLDWEGLARSVQTLVFYMGVKNL
TFICQQLITYGKSPSVPVIVIQWGTWGRQRSVKGTLQDIHQKIQEQQITNPAIIVIGDIV
NVQTHSWFESKPFIGQHMMIVTHGEDEHTLADKLRDYGADVIEWPKWRTEKMPANEDILG
QISTFEDIFFTSRRAVSEFFQALASKRIDIRQLTARLSAASEAGKAELIKRGFIISEHHH
NSPKKLIVGSRHSVEEMQKSESCLCYITHENVIDERFTRMTERTISESPLHMIICPGKQS
AQQLISAGEEIGISPEPSASRPPVICIGDGAAAAAYGFTAVQDQEQLFAFIQNEQVEKKL
LHS
NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atgatcatgaaaaacggaatcgtatattttgtgggcgccggacctggagatccagggctc
atcaccataaaaggaaaacaggcgctggaggaagcggatgtcattttgtatgaccggctc
gcaaaccctaagctgctcgaatacgcatcaccagactgccagttcatttattgcggaaaa
ctgccggaccgccattttatgaaacaagcagagatcaatgccctgctgattgaaaaagcg
tcggagggattaaccgttgtccgtttaaagggcggagatcccagcgtgtttggcagagtc
ggcgaggaagcagacgctctccaccagcatggcatccgctatgaaatggtgccgggcatc
acctcgggaatcgcagcgccgctgtatgcgggaatccccgtcacgcaccgggatttcgct
tcgtctttcgccatgattaccgcacatgataaatccttaaaaggaacgccgaaccttgac
tgggaagggcttgcccgaagcgttcaaacgcttgtgttttacatgggtgtcaaaaacctt
acatttatttgccagcagctcatcacgtacggaaaatctccttctgtccctgtcatcgtg
attcaatggggaacgtggggccgccagcggagcgtaaaaggaacgctgcaggatatccat
caaaaaatacaggaacagcaaatcacaaatcccgccattatcgtcatcggtgatattgta
aacgttcaaacacacagctggtttgaaagcaaaccattcatcgggcagcatatgatgata
gtcactcatggcgaagatgagcatacgctggcagacaagctgcgcgattatggtgccgat
gtcatcgaatggccaaaatggcggactgaaaaaatgcctgccaacgaggatattctagga
cagatcagcacctttgaggatattttcttcacatcacgccgtgcggttagcgaatttttt
caagcgctcgcgtccaaacgaatcgacattcgccagctgaccgcacgcctgagtgcagcg
tcagaagcaggaaaggcagagcttataaaacgcggcttcatcatatccgagcaccatcac
aattcacctaaaaagctgattgtcggcagccgtcattcagtagaagaaatgcagaaatca
gagtcctgtttgtgctatatcacccatgaaaacgtcatagatgagcgattcaccagaatg
accgaacggacgatcagtgagtctcctctgcacatgatcatttgccccggcaagcagtcc
gctcagcaattgatcagcgcaggagaagaaatcggcatttcaccagaaccgtcagcaagc
cgcccccctgtcatctgtataggcgatggcgcggccgccgctgcatatgggtttactgcc
gtacaagaccaagagcaattatttgcgtttatacaaaatgagcaagtggagaaaaagctc
ctccacagctga
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