Brevibacillus humidisoli: LOK74_13415
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Entry
LOK74_13415 CDS
T08900
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
bhui
Brevibacillus humidisoli
Pathway
bhui00860
Porphyrin metabolism
bhui01100
Metabolic pathways
bhui01110
Biosynthesis of secondary metabolites
bhui01120
Microbial metabolism in diverse environments
bhui01240
Biosynthesis of cofactors
Module
bhui_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
bhui00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LOK74_13415 (cobA)
Enzymes [BR:
bhui01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LOK74_13415 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LOK74_13415 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
ANF_receptor
Motif
Other DBs
NCBI-ProteinID:
UFJ39074
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Position
complement(2716051..2717589)
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AA seq
512 aa
AA seq
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MNRGKVYLVGAGPGDPKLLTIRGLETIQEADCIVYDRLVSPRLLANARVDAEMIYCGKLP
DRHTLTQEEINQVLVEKALDGKIVTRLKGGDPSIFGRVGEEAEELAKHDIPFEIVPGITS
GIAAPAYAGIPVTHRDFNSSLAIVTGHERPDKTDSSINWEKLATAVGTIIFYMGVGNLPF
IREQLIKYGRAPETPVALIRWGTTVEQQTVVGTLADIVEKREQAGLTNPAIIIVGEVVSL
RDRLQWFEKKPLFGKRVLVTRARSQASELSEQIMELGGEAYEFPLIKMVPPKELERLDEA
LWKLDQFDWVIFTSVNGVNHFFKRLRELRIDIRTMTGRLAAVGPKTAEALEAKGLTVSVL
PGEFRAEGLLERLKDELKPGQSVLLPRADVAREVLPKELRERGLNVTEADTYQTVIDAEN
SAETAALLKEKAIHIVTFTSSSTVKNFVQALEGYDLQELLAGVQVACIGPITAQTARDLG
LPVHIVATDSHIQGLVDAIIQSQGREKQDAAV
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgaacagaggaaaggtgtatttagtcggtgctggtccgggcgaccccaagctgcttacg
attcgcggattggagacgatccaggaggcggattgtatcgtatacgaccgtctggtcagc
ccgcgcctgttggccaacgccagagtagatgccgagatgatctactgcggcaagctaccg
gatcggcatacgcttacccaggaagagatcaatcaggtattggtggagaaagcgcttgac
ggtaaaatcgtcacccgtttgaagggaggcgacccttccatctttggccgggtgggcgaa
gaagcagaggaactggctaaacacgacatcccgtttgagattgtaccgggcatcacatcc
ggcatcgctgctccggcatacgccggaatcccggtgacccatcgtgattttaactcatcg
ctggccattgtcactggtcatgaacgtccagacaaaacggactcaagcattaattgggaa
aagctggccactgcggttgggacgatcatcttttacatgggagtgggcaatctgccgttt
atccgggaacagctgatcaaatacggacgcgcaccggaaacgccggtggcattgatccgt
tggggaaccacggtggaacagcagacggttgtcgggacgctggccgacatcgtagagaaa
cgggaacaggctggattgaccaatcccgcgatcatcatcgtgggggaagtggtttccctt
cgcgacaggctgcagtggtttgagaaaaagccgttgttcggcaagcgggtactggtcaca
agggcgcgcagtcaggccagcgagttgtcggagcagatcatggagctgggcggggaggca
tacgagtttccactgatcaagatggtcccgccaaaagagctggagcgactggatgaagca
ctgtggaaactggaccagtttgactgggttatctttaccagtgtcaacggtgtcaaccat
ttcttcaaacggctgcgtgaactgcgcatcgacattcgcacaatgacagggcgcctggcg
gcagtcggaccaaaaacggcagaagcgttggaagcgaaggggctgaccgtcagcgtgctg
ccgggagagttccgtgcggaagggctgctggaacggttgaaggacgagttgaagccaggt
cagtccgtgctgctgccgcgtgcggatgttgctcgtgaagttttgcctaaagaactgcga
gagcgtggactgaacgtaacggaagcagatacgtaccagacggtgatcgatgctgaaaac
agtgctgagacagctgcactgctgaaagaaaaagcgatccacatcgtcacctttaccagt
tcctcgactgtgaaaaacttcgtccaggcactggagggatacgatctgcaggaactgctt
gccggggtacaggttgcctgtatcggcccgataaccgctcagacggcacgtgacctggga
ctgcccgtacacatcgtcgcgaccgactctcacattcaagggctggtggatgccatcatc
caaagtcaggggagggagaaacaagatgcagccgtttga
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