Bos indicus (zebu cattle): 109555177
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Entry
109555177 CDS
T04792
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00010
Glycolysis / Gluconeogenesis
biu00020
Citrate cycle (TCA cycle)
biu00620
Pyruvate metabolism
biu00785
Lipoic acid metabolism
biu01100
Metabolic pathways
biu01200
Carbon metabolism
biu01210
2-Oxocarboxylic acid metabolism
biu04066
HIF-1 signaling pathway
biu04922
Glucagon signaling pathway
biu05230
Central carbon metabolism in cancer
biu05415
Diabetic cardiomyopathy
Module
biu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
109555177 (PDHA1)
00020 Citrate cycle (TCA cycle)
109555177 (PDHA1)
00620 Pyruvate metabolism
109555177 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
109555177 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
109555177 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109555177 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
109555177 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109555177 (PDHA1)
Enzymes [BR:
biu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
109555177 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
109555177
NCBI-ProteinID:
XP_019811373
UniProt:
A0A6P5AXB8
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All DBs
Position
X:complement(76084048..76106957)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRHFANDATFEIKKCDLHXLEEGPPVTXVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINXTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGXMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCNDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctctcgcgtgttgtcgggcgttgcccagaagccggca
agcagagtgctggtggcatctcgtcattttgcaaatgatgctacttttgaaattaagaaa
tgtgatcttcacyggctggaagagggccctcctgtcactayagtgcttaccagggaggat
ggrctcaaatactacaggatgatgcagaccgttcgccgaatggagttaaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtaggcctggaggccggcatcaacmccacagaccatctgatcacagcgtaccgggct
catggctttacctttactcgtggactctctgtccgggagatccttgcagagcttacagga
cgaagaggtggttgtgctaaaggaaaaggaggatyratgcatatgtatgccaagaatttc
tacggaggcaatggcatcgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagaygaggtctgtttgactttgtacggtgatggcgctgctaat
cagggtcagatattcgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggaragagcagcagccagcact
gattactacaagagaggcgactttattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggccacaaaatttgcagctgcctattgtagatctggaaaggggcctata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtgagt
taccgtacccgagaagagattcaggargttagaagtaagagtgaccctatcatgctcctc
aaggacaggatggtgaacagcaatctcgccagtgttgaagaactaaaggaaattgatgtg
gaagtgagaaaagaaattgaggatgctgctcagtttgctactgctgatcctgaaccacct
ttggaagaactcggctatcacatttactgcaacgatccaccttttgaagtccggggtgca
aaccagtggatcaagtttaagtccatcagttaa
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