Bos indicus (zebu cattle): 109555842 Help Entry 109555842         CDS       T04792                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04726   Serotonergic synapse biu04727   GABAergic synapse biu04728   Dopaminergic synapse biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04924   Renin secretion biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05012   Parkinson disease biu05030   Cocaine addiction biu05031   Amphetamine addiction biu05032   Morphine addiction biu05034   Alcoholism biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05207   Chemical carcinogenesis - receptor activation biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109555842 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109555842 (ADCY5)    04371 Apelin signaling pathway     109555842 (ADCY5)    04072 Phospholipase D signaling pathway     109555842 (ADCY5)    04024 cAMP signaling pathway     109555842 (ADCY5)    04022 cGMP-PKG signaling pathway     109555842 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109555842 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     109555842 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109555842 (ADCY5)    04062 Chemokine signaling pathway     109555842 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     109555842 (ADCY5)    04923 Regulation of lipolysis in adipocytes     109555842 (ADCY5)    04912 GnRH signaling pathway     109555842 (ADCY5)    04913 Ovarian steroidogenesis     109555842 (ADCY5)    04915 Estrogen signaling pathway     109555842 (ADCY5)    04914 Progesterone-mediated oocyte maturation     109555842 (ADCY5)    04921 Oxytocin signaling pathway     109555842 (ADCY5)    04926 Relaxin signaling pathway     109555842 (ADCY5)    04935 Growth hormone synthesis, secretion and action     109555842 (ADCY5)    04918 Thyroid hormone synthesis     109555842 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     109555842 (ADCY5)    04916 Melanogenesis     109555842 (ADCY5)    04924 Renin secretion     109555842 (ADCY5)    04925 Aldosterone synthesis and secretion     109555842 (ADCY5)    04927 Cortisol synthesis and secretion     109555842 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109555842 (ADCY5)    04270 Vascular smooth muscle contraction     109555842 (ADCY5)   09154 Digestive system    04970 Salivary secretion     109555842 (ADCY5)    04971 Gastric acid secretion     109555842 (ADCY5)    04972 Pancreatic secretion     109555842 (ADCY5)    04976 Bile secretion     109555842 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     109555842 (ADCY5)    04727 GABAergic synapse     109555842 (ADCY5)    04725 Cholinergic synapse     109555842 (ADCY5)    04728 Dopaminergic synapse     109555842 (ADCY5)    04726 Serotonergic synapse     109555842 (ADCY5)    04723 Retrograde endocannabinoid signaling     109555842 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109555842 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     109555842 (ADCY5)    04213 Longevity regulating pathway - multiple species     109555842 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     109555842 (ADCY5)    04714 Thermogenesis     109555842 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109555842 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     109555842 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109555842 (ADCY5)    05163 Human cytomegalovirus infection     109555842 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     109555842 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     109555842 (ADCY5)    05031 Amphetamine addiction     109555842 (ADCY5)    05032 Morphine addiction     109555842 (ADCY5)    05034 Alcoholism     109555842 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109555842 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109555842 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109555842 (ADCY5) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109555842 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  109555842 NCBI-ProteinID:  XP_019812241 UniProt:  A0A6P5B5X5 LinkDB All DBs Position 1:complement(68779454..68946733) Genome browser AA seq 1259 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPQAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDEDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGSGGGSVXXXXAAGGTEVRPRSVELGLEERRGKGRAADDLEAGAVEE DEGSGDGGSSAGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESSNPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI TLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGSSWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFNNNGTSQCPEHPTKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgactcccgcgccaat ggctacccccaagcccccgggggttctgcccgcggctccaccaagagacctgggggggcg gtgaccccgcagcagcaacagcgcctggccagccgctggcgcagcgacgacgaagacgat cctccgctgagtggcgatgaccccctggccgggggcttcggcttcagcttccgttccaag tcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcagcggcgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggcagcggcggcggttcggtg nnnnnnnnnnncgcagcgggcgggacggaagtgcgcccccgttcggtggagctaggcctg gaggagcggcgtggcaagggccgcgcggccgacgatctggaggccggcgccgtcgaggaa gacgaagggtccggggatgggggcagctcggcaggctcgggcgcggggcctggcgcggtg ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctctaagaagttccca tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctc acaatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttccacgcggca cggcccccgctgcagctgccctacctggccgtcctagcggccgccgtgggtgtgatcctc gttatggccgtgctctgcaaccgtgccgccttccaccaggaccacatgggcctggcctgc tacgcgcttatcgccgtggtgctggccgtccaggtggtgggcctgttgctgccccagccg cgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatctacacgctc ctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgccctccacctg gccatcgccctgcgcaccaacgcccaggatcagttcctgctcaagcagctcgtctccaac gtcctcattttctcctgcaccaacattgtgggtgtgtgcacccactacccggctgaggtc tcgcagaggcaggccttccaggagacccgggagtgcatccaggctcggctccactcacag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcacgttgccatg gagatgaaagccgacatcaacgccaaacaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcattctgtttgctgacatcgagggtttcaccagcctggca tcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggagattgttattactgt gtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggagatgggcatg gacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtgaacatgcgt gtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaagtggcagttc gatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggcaaggcggga cgcatccacatcaccaaggccactctcaactacttgaatggtgactacgaagtggagcca ggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacctttctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgattgccaagatgaaccgtcag agaaccaactccatcgggcacaacccgccccactggggggccgagcgccccttctataac cacctggggggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaatgcccaggaaagttcgaaccctgaggatgaagtggatgaatttctgggccgt gccattgatgccaggagcatcgacaggctgcgatctgaacatgttcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctacgtggcctgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccatt gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgaccttg gtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccagccccgctgcagacg ctctccaggaagatcgtgcggtccaagatgaacagcaccctggtgggggtgttcaccatc accctcgtgttcctgtcggctttcgtcaacatgttcacgtgcaactccaaggacctgttt ggctgcctgggggacgagcacaacatcagtgccagtcaggtcaatgcatgccacgtggtg gagtcggccgtcaactacagtctgggtgacgagcagggcttctgcggcagctcctggccc aactgcaacttccccgagtacttcacctatagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcatc tacgtgctcgtcgttgaggtgcccggtgtcacgctctttgacaatgccgacctactggtc acggccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcatccaacc aaggtggcgctgaaggtggtgacgcccatcatcatctccgtcttcgtgctggccctgtac ctgcatgcccagcaggtggagtccactgcccgcctcgacttcctctggaaacttcaggcc acggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac attctgcccaaggacgtggccgcacacttcctggcccgcgaacggcgcaacgacgagctc tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctctgag ttctacgtggaactagaggccaacaacgagggcgtcgagtgcctgcggctgctcaacgag atcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctggaaaagatc aagaccatcggcagcacctacatggccgcctccggcctcaatgactccacctacgacaag gtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatggaccaaatg aagtacatcaacgagcactctttcaacaacttccagatgaagatcgggctcaatattggc cccgtggtggcgggtgtgattggagcccgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca gacatgtaccaggtgctggccgccaatacgtaccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggaggacccccgcccagttag

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