KEGG   Brucella melitensis bv. 1 16M: BMEII0564
Entry
BMEII0564         CDS       T00072                                 
Name
(GenBank) proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
bme  Brucella melitensis bv. 1 16M
Pathway
bme00250  Alanine, aspartate and glutamate metabolism
bme00330  Arginine and proline metabolism
bme01100  Metabolic pathways
bme01110  Biosynthesis of secondary metabolites
Module
bme_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:bme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    BMEII0564
   00330 Arginine and proline metabolism
    BMEII0564
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:bme03000]
    BMEII0564
Enzymes [BR:bme01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     BMEII0564
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     BMEII0564
Transcription factors [BR:bme03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    BMEII0564
SSDB
Motif
Pfam: Aldedh Pro_dh Pro_dh-DNA_bdg PRODH Bombinin
Other DBs
NCBI-ProteinID: AAL53806
UniProt: Q8YCG6
LinkDB
Position
II:590616..594272
AA seq 1218 aa
MAVFQNFAPPIREQSALRQAITAAYRRPEAECVSALAEQATLPEETRQQIRSTARKLIEA
LRAKHKGTGIEGLVHEYSLSSQEGVALMCLAEALLRIPDMATRDALIRDKISNGDWKSHI
GGGRSLFVNAATWGLVVTGKLTNTVNDRGLSAALTRLIARCGEPVIRRGVDMAMRMMGEQ
FVTGETIDEALKRAKELEERGFRYSYDMLGEAATTAADAERYYKDYETAIHAIGRASAGR
GIYDGPGISIKLSALHPRYTRAQSERVMGELLPKVKALAAIAKSYNIGLNIDAEEADRLE
LSLDLLQSLCEDPDLAGWDGIGFVVQAYGKRCPLVLDFIIDLARRTKRRVMVRLVKGAYW
DAEIKRAQVDGLEDFPVYTRKVHTDVSYIACARKLLAATDVIFPQFATHNAQTLATIYHL
AGPDFKTGKFEFQCLHGMGEPLYDEVVGPEKLGRPARIYAPVGTHETLLAYLVRRLLENG
ANSSFVNRIGDKNVSVDELIADPVEVVRSMAVVGARHDQIALPENLYGARRNSAGFDLSN
EVTLAELSKTLKETAGRAWTAEPQVAGAKVKGVSRPVLNPGDRNDVVGTVTEIAEADVAK
AMKAAQTATTSWSAVAPAERAACLERAADIMQRDMPALLGLVMREAGKSMPNAIAEVREA
IDFLRYYAEQTRRTLGVGHKALGPVVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEET
PLIAAEGVRILHEGGIPADALQLLPGDGRIGAALVAAPETCGVMFTGSTEVARLIQAQLA
SRLLPNGKPVPLIAETGGQNAMIVDSSALAEQVVFDVIASAFDSAGQRCSALRVLCLQED
VADRILTMLKGALRELSIGRTDQLKVDIGPVITDEAKNTIEKHIQAMRDLGRKVEQLPLG
PETQNGTFVAPTIIEIESLRDLKREVFGPVLHVVRYKRDDMESLIDDINSTGYGLTFGLH
TRLDETIANVADRIRVGNIYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVETA
PIPPRHASVHTDAALKDFARWLGNRGMNDLAQAARDTGSASALGLELELPGPVGERNLYA
LHPRGRVLLVPQTEIGLYRQLTAVLATGNTAVIDEACGLRAVLKDLPETVAARAIWTGDW
QADAPFAGALIEGDSARIKEVNSRIAALPGPLVLTQAASPEDLAANQDAYCLNWLLEEVS
TSINTTAAGGNASLMAIG
NT seq 3657 nt   +upstreamnt  +downstreamnt
gtggccgttttccagaattttgcgccgccgatccgcgagcaaagcgcactgaggcaagcg
atcactgccgcttatcgccgccccgaagccgaatgcgtttcagcgctggccgagcaggca
accttgccggaggagacgcgccagcaaatccgttccaccgcccgcaagctgatcgaagcg
ctgcgtgccaagcataagggcaccggcatcgaaggtctggtgcatgaatattcgctgtcg
agccaggaaggcgtggcgctgatgtgccttgccgaagccttgctgcgcattcccgatatg
gcgacgcgcgatgcgctgatccgcgacaagatatcgaatggcgactggaaatcccacatt
ggcggcgggcgctcgcttttcgtcaatgctgcgacatggggcctggtcgttaccggcaag
ctcaccaataccgtcaatgatcgtggcctttccgccgctcttacccgcctcatcgcccgc
tgcggcgagccggtcatccgtcgcggcgtggacatggccatgcgcatgatgggcgagcag
ttcgtcaccggcgaaaccatcgatgaggcgttgaaacgcgccaaggagctggaagagcgc
ggcttccgctattcctacgacatgctgggcgaggccgcgaccaccgccgccgatgcagag
cgttattataaggattatgaaaccgcgatccacgccatcggtcgtgcttccgcagggcgc
ggcatttatgatggtcccggcatttccatcaagctttcggcgcttcacccgcgttatacc
cgcgcgcaaagtgagcgcgtcatgggtgaacttctgccgaaggtgaaggcactcgcggcc
atcgccaagtcctataatatcggcctcaatatcgacgcggaggaggccgaccgtcttgaa
ctgtcgctcgacctgttgcaaagcctttgcgaagaccctgatctggcaggctgggatggc
atcggcttcgtggtgcaggcctatggcaagcgctgccccctcgtgcttgatttcatcatc
gatctggctcgccgcaccaagcgccgcgtcatggtgcgtctggtgaagggcgcctattgg
gatgcggagatcaagcgtgcgcaggtggatgggctggaggattttccggtctatacccgc
aaggtgcatacggacgtttcctatattgcctgcgcgcgcaagcttctggccgcgacggat
gtgatctttccgcaatttgcgacccataacgcgcagacactcgccacgatctatcatctg
gccgggccggatttcaaaaccggtaagtttgagttccaatgcctgcacggcatgggtgag
ccgctttatgatgaagtcgtcggccccgaaaagctcggtcgcccggcccgcatttatgca
ccggtcggcacgcatgaaacgctgctcgcctatctcgtccgccgccttcttgaaaacggc
gcgaactcctccttcgtcaaccgtattggcgacaaaaacgtctcggtcgatgagctgatc
gccgatccggtggaagtcgtccggtcgatggctgtcgtcggtgcgcgtcatgaccagatt
gcgctgccggaaaatctctatggcgcgcgccgcaattccgcaggctttgatctttccaat
gaggtgacgcttgcggaactgagcaaaaccttgaaggaaacggcaggccgtgcatggacc
gccgaaccgcaggtggcgggtgcaaaggtgaagggcgtaagccgtccggttctcaatccc
ggcgaccggaatgatgttgtcggcaccgtaacggaaatcgcagaggccgatgtggcaaag
gcgatgaaggcagcgcaaaccgcgaccacaagctggtccgcggttgcgcccgcagaacgc
gccgcctgtctggagcgcgcagccgatatcatgcagcgcgacatgccggctctgctcggc
ctcgtcatgcgcgaggcgggcaagtccatgccgaacgccattgccgaagtgcgtgaagcc
atcgatttcctgcgctattatgccgaacagacccgccgcacgcttggcgtcggccacaag
gcgcttggccctgtcgtctgcatcagcccgtggaacttcccgctggcaatcttcaccggc
cagattgcggctgcacttgttgcaggcaatccggttctggcaaagcctgccgaggaaacc
ccgctgatcgccgctgagggcgtgcgcattctgcatgaggggggcattccggcggatgcg
ctccagcttctgccgggtgatggccgcattggcgccgcgctggttgcagcaccggaaact
tgcggcgtaatgttcaccggctccaccgaggtggcgcggctcatccaggcgcagcttgcc
tcgcgcctgctgccgaacggaaagccggtcccgctcattgccgaaacgggcggtcagaac
gccatgatcgtggattcctcggcacttgccgagcaggtggtgtttgatgtcatcgcttcg
gctttcgatagcgccggccagcgctgttcggcgctgcgtgtcctctgcttgcaggaagat
gtggccgaccgcattctcaccatgctcaagggcgccttgcgtgagctttccattggccgc
acggaccagctcaaggtcgatatcggcccggttatcaccgatgaggcgaagaacaccatt
gaaaagcatattcaggccatgcgcgatcttggccgcaaggtggaacagcttccccttggc
ccggaaacgcagaacggcacttttgttgcgccgacaatcatcgagattgaatcgctgcgc
gatctcaagcgcgaagtgttcggcccggtcctgcatgtggttcgttacaagcgcgacgac
atggaaagcctgatcgatgatatcaattcgaccggctatgggcttacttttggtttgcat
acgcgccttgacgagacgattgccaatgttgcggatcgcatccgtgtcggcaatatctat
atcaatcgcaacattatcggcgcagtggtgggcgtgcagcctttcggcgggcgtggcctt
tccggcaccggcccgaaggcgggcggtccgctctatcttggccgtctggtcgaaaccgcg
ccgatcccgccgcgtcacgcttcggttcataccgatgcggcgctgaaggactttgcccgg
tggctcggcaatcgcggcatgaacgatctggcgcaggcggcgcgcgataccggcagtgct
tcggcgctcggtctcgaactcgaactgccgggcccggttggcgagcgcaatctctatgct
ctccacccgcgcgggcgcgtgcttctggtcccccagaccgaaattggcctctatcgccaa
ttgacggcggtgctggcaaccggcaacactgcggtcatcgacgaggcttgcggtttgcgc
gccgtgttgaaggatctgccggaaacagttgccgcgcgcgccatctggacgggcgactgg
caggcggatgcgccttttgccggagcacttatcgaaggcgacagcgcgcgcatcaaggag
gtgaactccaggatcgccgccctgccgggaccgctcgtactcacacaggcggcatcgccg
gaagatcttgcagccaatcaggatgcttattgcctcaactggctgcttgaggaagtctcg
acctccatcaacaccacggcagcaggcggcaacgccagcctgatggcgatcggctga

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