Brugia malayi (filaria): BM_BM3889
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Entry
BM_BM3889 CDS
T01050
Symbol
Bma-gcs-1
Name
(RefSeq) glutamate--cysteine ligase, putative
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
bmy
Brugia malayi (filaria)
Pathway
bmy00270
Cysteine and methionine metabolism
bmy00480
Glutathione metabolism
bmy01100
Metabolic pathways
bmy01240
Biosynthesis of cofactors
bmy04212
Longevity regulating pathway - worm
Module
bmy_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
bmy00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
BM_BM3889 (Bma-gcs-1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
BM_BM3889 (Bma-gcs-1)
09150 Organismal Systems
09149 Aging
04212 Longevity regulating pathway - worm
BM_BM3889 (Bma-gcs-1)
Enzymes [BR:
bmy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
BM_BM3889 (Bma-gcs-1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
6096836
NCBI-ProteinID:
XP_001893383
UniProt:
A0A158T1F1
A0A4E9FFW5
LinkDB
All DBs
Position
Unknown
AA seq
652 aa
AA seq
DB search
MGLLTLGTPLSWNEIVPYVEYIKEHGIAQFIALYHRLKGREGDQLKWGDEIEYTIVKFDD
DAKKVRVSLRAEELLNQLQAGEELNALLGNDNCCLWRPEFAAYMIEGTPGAPYGGLLACF
NVVESNMISRRAEVTRLLKGDESVMSISFPSLGTPDFTSPSYEPRPDGDNNSGCSIFFPD
EAIYAGHPRFRNLVRNIKQRRGEKVAINVPIYKDINTPNPYQENFAQAKDGGQSARAAKP
DHIYMDHMGFGMGCCCLQVTFQAVNIDEARWLYDQLTPITPVLLALSAATPVFRSRLADV
DSRWDVISASVDDRTAEERGLLPLKNNKFVLKKSRYDTTDCYIYPCSESYNDIPLQYDDK
IYKQLIDGGIDNLLAQHVAHMFTRDPLQVYRERIEQDDMKTTEHFETVQSSNWMNMRFKP
PPPDSEIGWRVEFRPTEVQLTDFENAAYCCFVVLLTRVMISFRITLILPISVVTENMKRA
QRRNAVLEQKLLFRKRIATCNSPPCAKGAGCTLDSDDVVEMTVNEIINGSGEDFPGLIPL
MRQYLDSADVDVDSRCTVSQYLSFIQKRASGELQTLAAWMREFICKHPDYRHDSYVGDRI
IYDMLKKMDSISKGLVCCPELLGDYRTRTDSRIPMAVRRAEENLIVSHKQTQ
NT seq
1959 nt
NT seq
+upstream
nt +downstream
nt
atgggcttactaacgcttgggacgccattgtcatggaatgaaatagtaccctacgttgaa
tatattaaagaacacggtattgcacagttcattgctctgtatcatcgattgaaaggacgc
gaaggtgatcagctgaaatggggcgatgaaattgaatatacaattgttaagtttgatgat
gacgcaaagaaggttcgggtaagtttacgggcagaagagcttcttaatcaattgcaagct
ggtgaagagttgaatgcattgttgggtaatgataattgttgcttatggcgtccagaattt
gctgcatacatgattgaaggaacaccgggagcaccatatggaggcctgttagcatgcttt
aatgtagtggaaagtaacatgatatctcgtcgagctgaagttacacgattgttaaaaggt
gacgaatcagttatgtcaatatcatttccatctctgggtacaccagatttcacttcacct
tcatatgaaccacgtcctgatggtgataacaactctggttgttcaatatttttccctgat
gaagcaatttatgcaggacatccaagatttcggaatttggtaagaaatatcaaacaacgt
cgtggtgaaaaagttgccataaatgtaccaatatataaagatatcaatacacctaatcca
tatcaggaaaattttgcgcaagcaaaagatggtggtcaatctgcacgagcagcaaaacca
gatcatatttatatggatcatatgggttttggaatgggttgttgttgtttgcaagtcact
tttcaagctgtcaatattgacgaagcgagatggttatatgaccagttgacaccaataacg
cctgtattactggcattatcagctgctacacctgtttttcgatcacgattggctgatgtt
gattctcgttgggatgtcatatcagcgagtgttgacgatcgtacagctgaggaaagaggg
ttacttccattaaagaataataaatttgtattgaaaaaaagtcgatatgatactactgat
tgttatatctatccctgttctgaatcatataacgatataccgcttcaatatgacgacaag
atttataagcagttaatagatggtggaattgataaccttcttgcacagcatgttgcgcat
atgtttactcgtgatcctttacaggtatatcgtgaacgtatagagcaagatgacatgaag
acaactgaacattttgaaacagttcaaagttcaaattggatgaatatgcgtttcaaacca
cctccacctgattcagaaattggctggcgtgttgaatttcgaccaactgaagtgcaacta
acagatttcgaaaatgcagcttactgttgttttgttgtacttttaacaagggtaatgata
tcatttcgtatcactttgattttgcctatttctgttgttacggagaatatgaaacgtgca
cagcgtcgaaatgccgtactggaacaaaaactacttttccgtaaacgtattgcaacttgc
aattcacccccatgtgcaaagggagctggttgtacactcgattctgatgatgtggtggag
atgactgtcaatgaaatcatcaacgggagcggtgaagattttccaggattaataccacta
atgcgccaatatttagatagtgctgatgttgatgtggattcacgatgcaccgtatctcag
tatttaagctttatacagaaacgagcttctggcgagctgcaaacattggctgcttggatg
cgtgagtttatttgtaaacatcccgactacagacacgactcatatgtaggagatcgtatt
atctacgacatgttaaaaaagatggatagcatatcaaaaggattagtgtgctgtccagag
ttactgggtgattatcgtacaaggacagattcacgtataccgatggcagttcgtcgagcc
gaagaaaatttgattgtgagccataaacaaactcaataa
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