Bos mutus (wild yak): 102275901
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Entry
102275901 CDS
T02919
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase (lipoamide) alpha 1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00010
Glycolysis / Gluconeogenesis
bom00020
Citrate cycle (TCA cycle)
bom00620
Pyruvate metabolism
bom00785
Lipoic acid metabolism
bom01100
Metabolic pathways
bom01200
Carbon metabolism
bom01210
2-Oxocarboxylic acid metabolism
bom04066
HIF-1 signaling pathway
bom04922
Glucagon signaling pathway
bom05230
Central carbon metabolism in cancer
bom05415
Diabetic cardiomyopathy
Module
bom_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102275901 (PDHA1)
00020 Citrate cycle (TCA cycle)
102275901 (PDHA1)
00620 Pyruvate metabolism
102275901 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102275901 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102275901 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102275901 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102275901 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102275901 (PDHA1)
Enzymes [BR:
bom01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102275901 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
102275901
NCBI-ProteinID:
XP_005897781
UniProt:
L8IIP9
LinkDB
All DBs
Position
Un
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRHFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCNDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctctcgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatctcgtcattttgcaaatgatgctacttttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcactacagtgcttaccagggaggat
gggctcaaatactacaggatgatgcagaccgttcgccgaatggagttaaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtaggcttggaggccggcatcaaccccacagaccatctgatcacagcgtaccgggct
catggctttacctttactcgtggactctctgtccgggagatccttgcagagcttacagga
cgaagaggtggttgtgctaaaggaaaaggaggatcaatgcatatgtatgccaagaatttc
tacggaggcaatggcatcgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagacgaggtctgtttgactttgtacggcgatggcgctgctaat
cagggtcagatattcgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggaaagagcagcagccagcact
gattactacaagagaggcgactttattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggccacaaaatttgcagctgcctattgtagatctggaaaggggcctata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtgagt
taccgtacccgagaagagattcaggaagttagaagtaagagtgaccctatcatgctcctc
aaggacaggatggtgaacagcaatctcgccagtgttgaagaactaaaggaaattgatgtg
gaagtgagaaaagaaattgaggatgctgctcagtttgctactgctgatcctgaaccacct
ttggaagaactcggctatcacatttactgcaacgatccaccttttgaagtccggggtgca
aaccagtggatcaagtttaagtccatcagttaa
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