Bos mutus (wild yak): 102285848
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Entry
102285848 CDS
T02919
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom01522
Endocrine resistance
bom04010
MAPK signaling pathway
bom04015
Rap1 signaling pathway
bom04068
FoxO signaling pathway
bom04071
Sphingolipid signaling pathway
bom04114
Oocyte meiosis
bom04148
Efferocytosis
bom04218
Cellular senescence
bom04261
Adrenergic signaling in cardiomyocytes
bom04370
VEGF signaling pathway
bom04380
Osteoclast differentiation
bom04550
Signaling pathways regulating pluripotency of stem cells
bom04611
Platelet activation
bom04613
Neutrophil extracellular trap formation
bom04620
Toll-like receptor signaling pathway
bom04621
NOD-like receptor signaling pathway
bom04622
RIG-I-like receptor signaling pathway
bom04625
C-type lectin receptor signaling pathway
bom04657
IL-17 signaling pathway
bom04658
Th1 and Th2 cell differentiation
bom04659
Th17 cell differentiation
bom04660
T cell receptor signaling pathway
bom04664
Fc epsilon RI signaling pathway
bom04668
TNF signaling pathway
bom04670
Leukocyte transendothelial migration
bom04714
Thermogenesis
bom04722
Neurotrophin signaling pathway
bom04723
Retrograde endocannabinoid signaling
bom04728
Dopaminergic synapse
bom04750
Inflammatory mediator regulation of TRP channels
bom04912
GnRH signaling pathway
bom04914
Progesterone-mediated oocyte maturation
bom04917
Prolactin signaling pathway
bom04926
Relaxin signaling pathway
bom04932
Non-alcoholic fatty liver disease
bom04933
AGE-RAGE signaling pathway in diabetic complications
bom04935
Growth hormone synthesis, secretion and action
bom04936
Alcoholic liver disease
bom05014
Amyotrophic lateral sclerosis
bom05020
Prion disease
bom05022
Pathways of neurodegeneration - multiple diseases
bom05132
Salmonella infection
bom05133
Pertussis
bom05135
Yersinia infection
bom05140
Leishmaniasis
bom05142
Chagas disease
bom05145
Toxoplasmosis
bom05152
Tuberculosis
bom05161
Hepatitis B
bom05163
Human cytomegalovirus infection
bom05167
Kaposi sarcoma-associated herpesvirus infection
bom05169
Epstein-Barr virus infection
bom05170
Human immunodeficiency virus 1 infection
bom05171
Coronavirus disease - COVID-19
bom05205
Proteoglycans in cancer
bom05208
Chemical carcinogenesis - reactive oxygen species
bom05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bom05415
Diabetic cardiomyopathy
bom05417
Lipid and atherosclerosis
bom05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102285848 (MAPK12)
04015 Rap1 signaling pathway
102285848 (MAPK12)
04370 VEGF signaling pathway
102285848 (MAPK12)
04668 TNF signaling pathway
102285848 (MAPK12)
04068 FoxO signaling pathway
102285848 (MAPK12)
04071 Sphingolipid signaling pathway
102285848 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102285848 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
102285848 (MAPK12)
04218 Cellular senescence
102285848 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102285848 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102285848 (MAPK12)
04613 Neutrophil extracellular trap formation
102285848 (MAPK12)
04620 Toll-like receptor signaling pathway
102285848 (MAPK12)
04621 NOD-like receptor signaling pathway
102285848 (MAPK12)
04622 RIG-I-like receptor signaling pathway
102285848 (MAPK12)
04625 C-type lectin receptor signaling pathway
102285848 (MAPK12)
04660 T cell receptor signaling pathway
102285848 (MAPK12)
04658 Th1 and Th2 cell differentiation
102285848 (MAPK12)
04659 Th17 cell differentiation
102285848 (MAPK12)
04657 IL-17 signaling pathway
102285848 (MAPK12)
04664 Fc epsilon RI signaling pathway
102285848 (MAPK12)
04670 Leukocyte transendothelial migration
102285848 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
102285848 (MAPK12)
04914 Progesterone-mediated oocyte maturation
102285848 (MAPK12)
04917 Prolactin signaling pathway
102285848 (MAPK12)
04926 Relaxin signaling pathway
102285848 (MAPK12)
04935 Growth hormone synthesis, secretion and action
102285848 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
102285848 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
102285848 (MAPK12)
04723 Retrograde endocannabinoid signaling
102285848 (MAPK12)
04722 Neurotrophin signaling pathway
102285848 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102285848 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
102285848 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
102285848 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102285848 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
102285848 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102285848 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
102285848 (MAPK12)
05161 Hepatitis B
102285848 (MAPK12)
05171 Coronavirus disease - COVID-19
102285848 (MAPK12)
05163 Human cytomegalovirus infection
102285848 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
102285848 (MAPK12)
05169 Epstein-Barr virus infection
102285848 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
102285848 (MAPK12)
05135 Yersinia infection
102285848 (MAPK12)
05133 Pertussis
102285848 (MAPK12)
05152 Tuberculosis
102285848 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102285848 (MAPK12)
05140 Leishmaniasis
102285848 (MAPK12)
05142 Chagas disease
102285848 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102285848 (MAPK12)
05020 Prion disease
102285848 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
102285848 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102285848 (MAPK12)
05418 Fluid shear stress and atherosclerosis
102285848 (MAPK12)
05415 Diabetic cardiomyopathy
102285848 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102285848 (MAPK12)
04932 Non-alcoholic fatty liver disease
102285848 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
102285848 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102285848 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bom01001
]
102285848 (MAPK12)
Enzymes [BR:
bom01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102285848 (MAPK12)
Protein kinases [BR:
bom01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102285848 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kdo
APH
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
102285848
NCBI-ProteinID:
XP_005903977
LinkDB
All DBs
Position
Un
AA seq
346 aa
AA seq
DB search
MPVWVAFWPVTEAGPHARPCSSAYDTRLRQRVAVKKLSRPFQSLIHARRTYRELRLLKHL
KHENVIGLLDVFTPDETLDDFMDFYLVMPFMGTDLGKLMKHEKLSEDRVQFLVYQTLKGL
KYIHAAGVIHRDLKPSNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWM
HYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNY
MKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAERRVTAAEALAHPYFESLHDTEDDP
QAEKYDESFDDMDRTLDEWKRVTYKEVLSFKPPRQLGAKVSKETAL
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtgtgggtggccttctggccagtcaccgaggcggggcctcacgcgcggccttgc
agctcggcctacgacacgcggctgcgccagagggtggcggtgaagaagctgtcgcggccc
ttccagtctctgatccatgcgcggaggacctaccgggagctgcggctgctcaaacacctg
aagcacgagaacgtgattgggctgctggacgtgttcacgcccgatgagacgctggatgac
ttcatggacttctacctggtgatgccgttcatgggcaccgacctgggaaagctcatgaag
cacgagaagctgagcgaggaccgggtgcagttcctcgtctaccagacgctcaaggggctg
aagtacatccacgctgccggcgtcatccacagggacctgaagcctagcaacctggctgtg
aacgaggactgtgagctgaagatcctggactttggcctggcccggcaggcagacagcgag
atgaccggctacgtggtgacccggtggtaccgcgcgcccgaggtcatcttgaactggatg
cactacacgcagacggtggacatctggtccgtgggctgcatcatggccgagatgatcacg
gggaagacactcttcaaaggcaacgaccacctggaccagctgaaggagatcatgaaggtg
acggggacgcctcccgcggagtttgtgcagaggctgcaaagtgatgaggccaagaactac
atgaagggcctccctgagctggagaagaaggattttgcctccgtcctgaccaacgcgagc
cccctggccgtgagcctcctggagaaaatgctggtgctggatgcggagcggcgggtgacg
gcggccgaggcgctggcccacccctactttgagtcgctgcacgacacggaggacgatccc
caggccgagaagtacgatgagtcctttgacgacatggaccgcacgctggacgagtggaag
cgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaaggtc
tccaaggagacagccttgtga
DBGET
integrated database retrieval system