KEGG   Bos taurus (cow): 281736
Entry
281736            CDS       T01008                                 
Symbol
CXCR4
Name
(RefSeq) C-X-C chemokine receptor type 4
  KO
K04189  C-X-C chemokine receptor type 4
Organism
bta  Bos taurus (cow)
Pathway
bta03250  Viral life cycle - HIV-1
bta03260  Virion - Human immunodeficiency virus
bta04020  Calcium signaling pathway
bta04060  Cytokine-cytokine receptor interaction
bta04061  Viral protein interaction with cytokine and cytokine receptor
bta04062  Chemokine signaling pathway
bta04144  Endocytosis
bta04360  Axon guidance
bta04670  Leukocyte transendothelial migration
bta04672  Intestinal immune network for IgA production
bta04810  Regulation of actin cytoskeleton
bta05163  Human cytomegalovirus infection
bta05170  Human immunodeficiency virus 1 infection
bta05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    281736 (CXCR4)
   03260 Virion - Human immunodeficiency virus
    281736 (CXCR4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    281736 (CXCR4)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    281736 (CXCR4)
   04061 Viral protein interaction with cytokine and cytokine receptor
    281736 (CXCR4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    281736 (CXCR4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    281736 (CXCR4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    281736 (CXCR4)
   04672 Intestinal immune network for IgA production
    281736 (CXCR4)
   04062 Chemokine signaling pathway
    281736 (CXCR4)
  09158 Development and regeneration
   04360 Axon guidance
    281736 (CXCR4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    281736 (CXCR4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    281736 (CXCR4)
   05163 Human cytomegalovirus infection
    281736 (CXCR4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:bta04030]
    281736 (CXCR4)
   04050 Cytokine receptors [BR:bta04050]
    281736 (CXCR4)
   04090 CD molecules [BR:bta04090]
    281736 (CXCR4)
G protein-coupled receptors [BR:bta04030]
 Rhodopsin family
  Chemokine
   CXC Chemokine
    281736 (CXCR4)
Cytokine receptors [BR:bta04050]
 Chemokine receptors
  CXC Chemokine
   281736 (CXCR4)
CD molecules [BR:bta04090]
 Proteins
  281736 (CXCR4)
SSDB
Motif
Pfam: 7tm_1 CXCR4_N 7TM_GPCR_Srsx DUF4538
Other DBs
NCBI-GeneID: 281736
NCBI-ProteinID: NP_776726
BGD-bta: BT27276
Ensembl: ENSBTAG00000001060
VGNC: 27856
UniProt: P25930
LinkDB
Position
2:61250149..61253862
AA seq 353 aa
MEGIRIFTSDNYTEDDLGSGDYDSMKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLV
ILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVN
LYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWLPAVLLTIPDLIFADIKE
VDERYICDRFYPSDLWLVVFQFQHIVVGLLLPGIVILSCYCIIISKLSHSKGYQKRKALK
TTVILILTFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNP
ILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
NT seq 1062 nt   +upstreamnt  +downstreamnt
atggaagggatccgtatattcacttccgataattacaccgaggatgacttgggctcgggt
gactatgattccatgaaggaaccctgcttccgggaagaaaatgcccatttcaaccggatc
ttcctgcccactgtctactccatcatcttcctgactggcatagtgggcaacggattggtc
attctggtcatgggttaccagaagaaactaagaagcatgacggacaagtacagactgcac
ctgtctgtggcggacctcctgtttgtcctcacgcttcccttctgggcagtcgatgctgtg
gcaaactggtactttgggaagttcctctgcaaggcagtccatgtcatctacacagtcaac
ctctacagcagtgtcctcatcctggcctttatcagtctggaccggtacctggctatcgtc
catgctaccaacagtcagaagccaaggaagctgctggctgaaaaggtggtctatgttggt
gtctggctacctgctgtcctgttgactattcctgatctcatctttgctgacatcaaggag
gtggatgagaggtacatctgtgatcgcttctatcccagcgacctgtggctagtggtgttt
cagtttcagcacatcgtggtcggccttctcctgcctggtatcgtcatcctgtcctgctac
tgcattatcatctccaagctgtcccactccaaaggctatcagaagcgcaaggccctcaag
accacagttatcctcatcctgactttcttcgcctgctggctgccctactacattgggatc
agcattgactccttcatccttctggaaatcatccagcaagggtgtgagtttgagagcact
gtgcacaagtggatttccatcaccgaggccctagctttttttcactgctgcctgaatccc
atcctctatgccttccttggggccaaatttaaaacctctgcccagcatgcactcacctct
gtgagcagagggtccagcctgaagatcctctccaagggcaagcgaggtggacattcttct
gtctcaaccgagtctgaatcttcaagttttcactccagctaa

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