Bos taurus (cow): 282876 Help Entry 282876            CDS       T01008                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism bta  Bos taurus (cow) Pathway bta00220   Arginine biosynthesis bta00330   Arginine and proline metabolism bta01100   Metabolic pathways bta04020   Calcium signaling pathway bta04066   HIF-1 signaling pathway bta04146   Peroxisome bta04371   Apelin signaling pathway bta04926   Relaxin signaling pathway bta05010   Alzheimer disease bta05014   Amyotrophic lateral sclerosis bta05022   Pathways of neurodegeneration - multiple diseases bta05133   Pertussis bta05140   Leishmaniasis bta05142   Chagas disease bta05145   Toxoplasmosis bta05146   Amoebiasis bta05152   Tuberculosis bta05200   Pathways in cancer bta05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     282876 (NOS2)    00330 Arginine and proline metabolism     282876 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     282876 (NOS2)    04066 HIF-1 signaling pathway     282876 (NOS2)    04020 Calcium signaling pathway     282876 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     282876 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     282876 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     282876 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     282876 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     282876 (NOS2)    05152 Tuberculosis     282876 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     282876 (NOS2)    05145 Toxoplasmosis     282876 (NOS2)    05140 Leishmaniasis     282876 (NOS2)    05142 Chagas disease     282876 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     282876 (NOS2)    05014 Amyotrophic lateral sclerosis     282876 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     282876 (NOS2) Enzymes [BR:bta01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      282876 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  282876 NCBI-ProteinID:  NP_001070267 BGD-bta:  BT15434 Ensembl:  ENSBTAG00000006894 VGNC:  32173 UniProt:  Q27995 LinkDB All DBs Position 19:complement(19388579..19431356) Genome browser AA seq 1156 aa AA seqDB search MACPWQFLFKIKSQKVDLATELDINNNVGKFYQPPSSPVTQDDPKRHSPGKHGNESPQPL TGTVKTSPESLSKLDAPPSACPRHVRIKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIM NPKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG RFDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEVGVRDFCDAQRYNILEEVGRRMGLETHKVASLWKDRAVVEINV AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM LNYVLSPFYYYQVEPWKTHVWQDERRRPQRREIRFKVLVKAVFFASVLMHKAMASRVRAT ILFATETGRSETLAQDLGALFSCAFNPKVLCMDQYQLSHLEEEQLLLVVTSTFGNGDSPG NGEKLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGD ELSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPQHYRLVQDSEPLDL NKALSSMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQ PALVQGILERVVDGPAPHQPVRLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQ LLLRKLAQLATEEAEKQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQL PILKPRYYSISSSRDLTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF VRSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPE EDHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLY VCGDVRMARDVARTLKQLMATALSLNEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDG AAGLPSNPRAPGAHRS NT seq 3471 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccctggcagtttctgttcaaaatcaaatcccaaaaggtggacttggctacg gaactggacatcaacaacaatgtgggaaaattctaccagcccccgtccagtccagtgaca caggatgaccccaaacgtcacagcccgggcaagcacgggaatgagtctccccagcccctc acggggacagtaaagacgtctccagaatccctgagcaagctggacgcgcccccgtcagcc tgtccacggcatgtgaggatcaaaaactggggcagcggagtgactttccaagacacgctt caccagaaggccaaaggggatctctcttgcaagtccaagtcttgcctggcatccatcatg aaccccaaaagtttgaccataggaccccgggacaagccaacccccccagacgagcttcta cctcaagctatcgaatttgtcaaccagtattacggctccttcaaagaggcaaaaatagag gaacatctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctaccag ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaacgccccccgctgc atcggaaggatccagtggtcgaacctgcaggtctttgacgcccggagctgttccacggcc caggaaatgttcgaacacatctgcagacacgtgcgttatgccaccaacaacggcaacatc aggtcggccatcactgtgttcccccagcggagcgatgggaagcatgacttccgggtctgg aacgcccagctcatccgctatgccggctaccagatgccagatggcagcatcagaggggac cccgccaacgtggagttcacacagctgtgcatcgacctgggctggaagcccaagtacggc cgcttcgacgtgttgcctctagtcctgcaggctgacggccgtgacccagagctcttcgaa atcccccctgaccttgttctcgaggtgcccatggaacatcccaggtacgaatggttccgg gagctggagctcaagtggtacgccctgccagccgtggccaacatgctgcttgaggtgggc ggcctcgagttcccagggtgccccttcaacgggtggtacatgggcacagaagttggagtc cgggacttctgcgacgcccagcgatacaacatcctggaggaagtgggcagaaggatgggc ctggaaacgcacaaggtggcctcactctggaaggaccgggctgtcgttgagatcaacgtc gctgtgctccacagtttccagaagcagaacgtgaccatcatggaccaccactccgctgca gagtccttcatgaagtacatgcagaatgagtaccgctcccgagggggctgcccagctgac tggatttggctggtccccccgatctctggaagcatcacccccgtgttccaccaggagatg ttaaattacgtcctgtcccctttctactactaccaggtggagccctggaaaacccacgtc tggcaggacgagaggcggagaccccagagaagagaaattcgattcaaagtcttggtcaaa gccgtgttcttcgcctcggtgctgatgcataaggccatggcatcccgggtcagagccacg atcctctttgcaacagagacggggagatcggaaacgctggcccaggacctgggggctttg ttcagctgtgccttcaaccccaaggttctctgcatggatcagtaccagctgagccatctg gaggaggarcagctgctgctggtggtgaccagcacttttggcaacggagactcccctggc aacggagagaaactgaagaagtccctcttgatgctgaaagaactcaccaacacgttccgg tacgccgtgtttggccttggctccagcatgtaccctcagttctgcgcttttgctcatgac attgaccagaagttgtcccagctgggggcttctcagcttgccccaaccggggaaggggac gaactcagcgggcaggaggaggcctttcgcagctgggccgtgcaaaccttcaaggcagcc tgtgagacattcgatgtcagcggcaagcaccacattgagatccccaagctctacacttcc aatgtgacctgggacccgcagcactacaggctcgtgcaggactcagagcctctggacctc aacaaagccctgagcagtatgcacgccaagcatgtgttcaccatgaggctcaaatcgcag cagaatctgcagagtccgaaatccagccgcaccaccctcctggtggaactctcctgtgag ggcagccaagctccaagctacctgccgggagagcacctcggagttttcccatgcaaccag ccggccctggttcaaggcatccttgagcgagtggtggatggccctgccccgcaccagcct gtgcgcctggagaccctctgtgagaatggcagctattgggtcaaggataagcggctgcca ccttgctcactcagccaggctctcacctatttcctggacatcaccaccccgccaacccag ctgctgctccgaaagctggcccagctggccacagaagaggctgagaagcagaggctggag accctatgccagccctcagattacaacaagtggaagttcaccaacagccccacatttctg gaggtgctggaggagttcccgtccctgcgggtgtctgccagcttcctgctctcccagctc cctattctgaagccccggtactactccatcagctcctccagggacctcacacccacggag atccacctcactgtggccgtgctcacgtaccgcacccgagatggccaaggtcccctgcac catggtgtctgcagcacgtggctcagcagcttgaagccccaagacccggtgccctgcttt gtgcgaagtgccagyggcttccagcttcccgaggaccgctcccgtccttgcatcctcatt gggcccggcacgggcatcgcccccttccgcagtttctggcagcagcggctccatgaggct gagcacaaagggctccagggcggccgcatgaccctggttttcgggtgccgccgcccagaa gaggaccacctctactgggaggagatgctggagatggcccgcaagggggtgctgcacgag gtgcacaccgcctattcccgcctgcctgaccagcccaaggtctatgttcaagacatcctg cggcagcggctggcgggcgaggtgcttcgcgtgctccatgaggagcaaggtcacctctat gtctgtggggatgtgcgcatggcccgggacgtggcccgcaccctgaagcagctgatggct actgcgctgagcctgaacgaggaacaggtggaggactatttcttccagctcaagaaccag aagcgctatcatgaagacatctttggtgctgtatttccctatgaggtgaaaaaggatggg gcagcagggctgcccagcaatcccagagctccaggcgcccacagaagttaa

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