Bos taurus (cow): 512943
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Entry
512943 CDS
T01008
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
bta
Bos taurus (cow)
Pathway
bta01522
Endocrine resistance
bta04010
MAPK signaling pathway
bta04015
Rap1 signaling pathway
bta04068
FoxO signaling pathway
bta04071
Sphingolipid signaling pathway
bta04114
Oocyte meiosis
bta04148
Efferocytosis
bta04218
Cellular senescence
bta04261
Adrenergic signaling in cardiomyocytes
bta04370
VEGF signaling pathway
bta04380
Osteoclast differentiation
bta04550
Signaling pathways regulating pluripotency of stem cells
bta04611
Platelet activation
bta04613
Neutrophil extracellular trap formation
bta04620
Toll-like receptor signaling pathway
bta04621
NOD-like receptor signaling pathway
bta04622
RIG-I-like receptor signaling pathway
bta04625
C-type lectin receptor signaling pathway
bta04657
IL-17 signaling pathway
bta04658
Th1 and Th2 cell differentiation
bta04659
Th17 cell differentiation
bta04660
T cell receptor signaling pathway
bta04664
Fc epsilon RI signaling pathway
bta04668
TNF signaling pathway
bta04670
Leukocyte transendothelial migration
bta04714
Thermogenesis
bta04722
Neurotrophin signaling pathway
bta04723
Retrograde endocannabinoid signaling
bta04728
Dopaminergic synapse
bta04750
Inflammatory mediator regulation of TRP channels
bta04912
GnRH signaling pathway
bta04914
Progesterone-mediated oocyte maturation
bta04917
Prolactin signaling pathway
bta04926
Relaxin signaling pathway
bta04932
Non-alcoholic fatty liver disease
bta04933
AGE-RAGE signaling pathway in diabetic complications
bta04935
Growth hormone synthesis, secretion and action
bta04936
Alcoholic liver disease
bta05014
Amyotrophic lateral sclerosis
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05132
Salmonella infection
bta05133
Pertussis
bta05135
Yersinia infection
bta05140
Leishmaniasis
bta05142
Chagas disease
bta05145
Toxoplasmosis
bta05152
Tuberculosis
bta05161
Hepatitis B
bta05163
Human cytomegalovirus infection
bta05167
Kaposi sarcoma-associated herpesvirus infection
bta05169
Epstein-Barr virus infection
bta05170
Human immunodeficiency virus 1 infection
bta05171
Coronavirus disease - COVID-19
bta05205
Proteoglycans in cancer
bta05208
Chemical carcinogenesis - reactive oxygen species
bta05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bta05415
Diabetic cardiomyopathy
bta05417
Lipid and atherosclerosis
bta05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
512943 (MAPK12)
04015 Rap1 signaling pathway
512943 (MAPK12)
04370 VEGF signaling pathway
512943 (MAPK12)
04668 TNF signaling pathway
512943 (MAPK12)
04068 FoxO signaling pathway
512943 (MAPK12)
04071 Sphingolipid signaling pathway
512943 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
512943 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
512943 (MAPK12)
04218 Cellular senescence
512943 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
512943 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
512943 (MAPK12)
04613 Neutrophil extracellular trap formation
512943 (MAPK12)
04620 Toll-like receptor signaling pathway
512943 (MAPK12)
04621 NOD-like receptor signaling pathway
512943 (MAPK12)
04622 RIG-I-like receptor signaling pathway
512943 (MAPK12)
04625 C-type lectin receptor signaling pathway
512943 (MAPK12)
04660 T cell receptor signaling pathway
512943 (MAPK12)
04658 Th1 and Th2 cell differentiation
512943 (MAPK12)
04659 Th17 cell differentiation
512943 (MAPK12)
04657 IL-17 signaling pathway
512943 (MAPK12)
04664 Fc epsilon RI signaling pathway
512943 (MAPK12)
04670 Leukocyte transendothelial migration
512943 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
512943 (MAPK12)
04914 Progesterone-mediated oocyte maturation
512943 (MAPK12)
04917 Prolactin signaling pathway
512943 (MAPK12)
04926 Relaxin signaling pathway
512943 (MAPK12)
04935 Growth hormone synthesis, secretion and action
512943 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
512943 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
512943 (MAPK12)
04723 Retrograde endocannabinoid signaling
512943 (MAPK12)
04722 Neurotrophin signaling pathway
512943 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
512943 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
512943 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
512943 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
512943 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
512943 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
512943 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
512943 (MAPK12)
05161 Hepatitis B
512943 (MAPK12)
05171 Coronavirus disease - COVID-19
512943 (MAPK12)
05163 Human cytomegalovirus infection
512943 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
512943 (MAPK12)
05169 Epstein-Barr virus infection
512943 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
512943 (MAPK12)
05135 Yersinia infection
512943 (MAPK12)
05133 Pertussis
512943 (MAPK12)
05152 Tuberculosis
512943 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
512943 (MAPK12)
05140 Leishmaniasis
512943 (MAPK12)
05142 Chagas disease
512943 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
512943 (MAPK12)
05020 Prion disease
512943 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
512943 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
512943 (MAPK12)
05418 Fluid shear stress and atherosclerosis
512943 (MAPK12)
05415 Diabetic cardiomyopathy
512943 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
512943 (MAPK12)
04932 Non-alcoholic fatty liver disease
512943 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
512943 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
512943 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
512943 (MAPK12)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
512943 (MAPK12)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
512943 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kdo
APH
Kinase-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
512943
NCBI-ProteinID:
NP_001092423
BGD-bta:
BT16381
Ensembl:
ENSBTAG00000019574
VGNC:
31215
UniProt:
A5PJL3
LinkDB
All DBs
Position
5:complement(119618818..119626764)
Genome browser
AA seq
367 aa
AA seq
DB search
MSSPSSARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFMDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQTLKGLKYIHAAGVIHRDLKPSNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAERRV
TAAEALAHPYFESLHDTEDDPQAEKYDESFDDMDRTLDEWKRVTYKEVLSFKPPRQLGAK
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgtcgtccgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcagcccgtgggctcgggcgcctacggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccatcaagaagctgtaccgg
ccctttcagtctgagctgttcgccaagcgcgcctaccgggagctgcgcctcctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcacgcccgatgagacgctggat
gacttcatggacttctacctggtgatgccgttcatgggcaccgacctgggaaagctcatg
aagcacgagaagctgagcgaggaccgggtgcagttcctcgtctaccagacgctcaagggg
ctgaagtacatccacgctgccggcgtcatccacagggacctgaagcctagcaacctggct
gtgaacgaggactgtgagctgaagatcctggactttggcctggcccggcaggcagacagc
gagatgaccggctacgtggtgacccggtggtaccgcgcgcccgaggtcatcttgaactgg
atgcactacacgcagacggtggacatctggtccgtgggctgcatcatggccgagatgatc
acggggaagacactcttcaaaggcaacgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctcctgcggagtttgtgcagaggctgcaaagtgatgaggccaagaac
tacatgaagggcctccctgagctggagaagaaggattttgcctccgtcctgaccaacgcg
agccccctggccgtgagcctcctggagaaaatgctggtgctggatgcggagcggcgggtg
acggcggccgaggcgctggcccacccctactttgagtcgctgcacgacacggaggacgat
ccccaggccgagaagtacgatgagtcctttgacgacatggaccgcacgctggacgagtgg
aagcgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gtctccaaggagacagccttgtga
DBGET
integrated database retrieval system