Bos taurus (cow): 515515 Help Entry 515515            CDS       T01008                                  Symbol SYK Name (RefSeq) tyrosine-protein kinase SYK   KO K05855   spleen tyrosine kinase [EC:2.7.10.2] Organism bta  Bos taurus (cow) Pathway bta04064   NF-kappa B signaling pathway bta04072   Phospholipase D signaling pathway bta04151   PI3K-Akt signaling pathway bta04380   Osteoclast differentiation bta04611   Platelet activation bta04613   Neutrophil extracellular trap formation bta04625   C-type lectin receptor signaling pathway bta04650   Natural killer cell mediated cytotoxicity bta04662   B cell receptor signaling pathway bta04664   Fc epsilon RI signaling pathway bta04666   Fc gamma R-mediated phagocytosis bta05152   Tuberculosis bta05167   Kaposi sarcoma-associated herpesvirus infection bta05168   Herpes simplex virus 1 infection bta05169   Epstein-Barr virus infection bta05171   Coronavirus disease - COVID-19 bta05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     515515 (SYK)    04072 Phospholipase D signaling pathway     515515 (SYK)    04151 PI3K-Akt signaling pathway     515515 (SYK)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     515515 (SYK)    04613 Neutrophil extracellular trap formation     515515 (SYK)    04625 C-type lectin receptor signaling pathway     515515 (SYK)    04650 Natural killer cell mediated cytotoxicity     515515 (SYK)    04662 B cell receptor signaling pathway     515515 (SYK)    04664 Fc epsilon RI signaling pathway     515515 (SYK)    04666 Fc gamma R-mediated phagocytosis     515515 (SYK)   09158 Development and regeneration    04380 Osteoclast differentiation     515515 (SYK)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     515515 (SYK)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     515515 (SYK)    05168 Herpes simplex virus 1 infection     515515 (SYK)    05167 Kaposi sarcoma-associated herpesvirus infection     515515 (SYK)    05169 Epstein-Barr virus infection     515515 (SYK)   09171 Infectious disease: bacterial    05152 Tuberculosis     515515 (SYK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bta01001]     515515 (SYK) Enzymes [BR:bta01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      515515 (SYK) Protein kinases [BR:bta01001]  Non-receptor tyrosine kinases   SYK family    515515 (SYK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1 RIO1 Motif Other DBs NCBI-GeneID:  515515 NCBI-ProteinID:  NP_001032542 BGD-bta:  BT18159 Ensembl:  ENSBTAG00000004767 VGNC:  35513 UniProt:  Q32PK0 Structure PDB LinkDB All DBs Position 8:complement(86975440..87083485) Genome browser AA seq 605 aa AA seqDB search MGDGANNLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHDRKAHHYT IERELNGTYAITGGRAHGSPAELCHYHTQELDGLVCLLKKPFNRPPGVQPKTGPFEDLKE NLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIG SKTNGKFLIRAKDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPGGKNFDTLWQLVEHYSY KSDGLLRVLTVPCQKIGGQSGNINFRPQLPSSHPGTRTSSGNQVDSSTTFNPYEPDRGPW ANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYY QMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEM AELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKI SDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQ KPYRGMKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYY YDVVN NT seq 1818 nt NT seq  +upstreamnt  +downstreamnt atgggtgacggcgccaacaacctgcccttcttcttcggcaacatcactcgggaggaggcg gaagactacctggtccaggggggcatgagcgatgggctctacctgctgcgccagagccgc aactacctgggtggctttgccctgtcagtggcacacgacagaaaggcacatcactacacc atcgagagggagctgaatggcacctatgccatcacgggtggccgggcccatggcagtcca gccgagctctgccactaccacacccaggagctggatggcctcgtctgcctcctcaagaag cccttcaaccggccgccgggggtgcagcccaagactggaccctttgaggacttgaaggag aacctcatccgagaatacgtgaaacagacatggaacctacagggtcaagctcttgagcag gccatcatcagccagaaacctcagctggagaaactgatcgccaccacagctcatgaaaaa atgccctggttccatggaaaaatctctcgggatgaatctgagcagattgtcctgatagga tcaaagacgaatggaaagttcttgatcagggccaaggacaacgggtcctacgccctgtgc ctgctgcacgagggcaaggtgctgcactaccgcatcgacaaggacaaaacggggaagctc tccatccctggcgggaagaatttcgacacactctggcagctggtcgagcattattcttat aaatcagatggtttgttaagagttcttacagttccatgtcaaaaaattggcgggcaatcg ggaaatattaacttccgtccacaacttccaagttctcatcctgggacccgcacatcctca gggaaccaggtggatagttctacaacattcaacccttacgagccagaccgaggaccgtgg gccaacgagagagaagctcagagagaagccttgcccatggacactgaggtctacgaaagc ccctatgcagaccccgaggagatccggcccaaggaggtctacctggaccggaagctgctg accctggaggacaaggaactgggctctgggaactttgggactgtgaagaagggctattac cagatgaaaaaagttgtgaaaacagtggctgtgaaaatcctgaaaaatgaggccaatgac cctgctcttaaggatgagttattagcagaagcgaatgtcatgcagcagcttgacaaccct tacattgtgcgcatgatagggatatgtgaagctgagtcctggatgctggtcatggagatg gcagaacttggtccactcaacaaatatttacaacagaacaggcatgtcaaggataaaaac atcatagagctggttcatcaggtgtctatgggaatgaaatatttggaagaatgcaatttt gtgcacagagatctggctgcaaggaatgtcttgctggttactcaacattatgccaagatc agtgattttggactttccaaagcacttcgtgctgatgaaaactactacaaggcccagacc cacggaaagtggcctgtgaagtggtatgctccggaatgcatcaactactacaagttctcc agcaagagtgatgtttggagcttcggagtgttgatgtgggaagcgttttcctacgggcag aagccatatcggggaatgaaaggcagtgaagtttctgctatgctggagaaaggagagagg atggggtgcccaccagggtgtccgagagagatgtacgagctgatgaccctgtgctggacc tatgacgtggagaacaggcctggattcgtagctgtggaactgcggctgcgcaattactac tacgacgtggttaactaa

DBGET integrated database retrieval system