Burkholderia sp. JP2-270: DM992_30695
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Entry
DM992_30695 CDS
T07766
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
burk
Burkholderia sp. JP2-270
Pathway
burk00790
Folate biosynthesis
burk01100
Metabolic pathways
burk01240
Biosynthesis of cofactors
Module
burk_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
burk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
DM992_30695
Enzymes [BR:
burk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
DM992_30695
6.3.2.17 tetrahydrofolate synthase
DM992_30695
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Phage_Mu_Gp27
Motif
Other DBs
NCBI-ProteinID:
AWV03587
UniProt:
A0A2U9SXL3
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All DBs
Position
2:2768041..2769351
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AA seq
436 aa
AA seq
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MSTFPTLDAWLSHLERAHPVGIDMGLTRIGQVKAALQLEFTCPVITVGGTNGKGSTCAFL
ETILVRAGYKVGCHTSPHLLEFNERARVNGQNVTDDELLPHFEAVEAARTSLPEPVSLTY
FEFTTLAILHLFASRGLDAVILEVGLGGRLDAVNIVDTDCAIVTSIDIDHTEYLGDTREK
IAFEKAGIFRTGKPAICGDPAAPQTLVDHAEAIGADLWLVGRDFRYEAQAGAERQQWSYL
GREKRYPALAYPALRGANQLINASAALAALEALRPVLPVSAQDIRLGLANVELPGRFQVL
PGKPAIVLDVAHNPHAAAVLEQNLGNMGFFPYTYAVFGAMHDKDIDGVLRHLKGEIDHWC
VTDLPLPRAASAEQLEAALRKAGVEDGADSSVTRYASPAEAFRDALKRASENDRIVVFGS
FHTVAGVLAYRKSQQH
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgagcacttttcccactctcgacgcgtggctctcgcaccttgaacgcgcgcacccggtc
ggcatcgacatgggcctgacccgcatcgggcaggtcaaggcggcgctgcagctcgaattc
acgtgccccgtcatcaccgtcggcggcacgaacggcaagggctcgacctgcgcattcctc
gagacgatcctcgtgcgcgcgggctacaaggtcggctgccacacgtcgccgcacctgctc
gaattcaacgagcgcgcgcgcgtgaacgggcagaacgtcaccgacgacgaactgctgccg
cacttcgaggccgtcgaagccgcgcgcacatcgctgccggaaccggtgtcgctcacgtac
ttcgaattcacgacgctcgcgatcctgcatctgttcgcgtcgcgcgggctcgatgcggtg
atcctcgaagtcggcctcggcggccggctcgatgcggtcaacatcgtcgataccgattgc
gcgatcgtcacgagcatcgacatcgaccacaccgaatacctcggcgacacgcgcgagaag
atcgcgttcgagaaggccggaatcttccgtaccggcaagccggcgatctgcggcgatccg
gccgcgccgcagacgctcgtcgaccacgccgaagcgatcggcgccgacctgtggctcgtc
ggccgcgatttccgctacgaggcgcaggcgggcgcggagcgccagcagtggagttacctc
ggccgcgagaagcgctatccggcgctcgcgtatccggcgctgcgcggcgcgaatcagctg
atcaatgcatcggccgcgctcgcggcgctcgaggcgctgcgcccggtgctgccggtgtcc
gcgcaggacatccggctcgggctcgcgaacgtcgagctgccggggcgcttccaggtgctg
cccggcaagccggcgatcgtgctcgacgtcgcgcacaacccgcatgcggcggccgtgctc
gagcagaatctcggcaacatgggctttttcccgtacacgtacgcggtgttcggcgcgatg
cacgacaaggacatcgacggtgtgctgcggcacctgaaaggcgagatcgaccactggtgc
gtgaccgacctgccgctgccgcgcgcggcctccgcggagcagctcgaagccgcgctgcgc
aaggccggcgtggaggacggggccgattcgagcgtgacgcgttacgcgtcgccggcggaa
gcgtttcgcgatgcactaaaaagagcatccgagaatgatagaatcgtggttttcggcagt
ttccatacggttgccggcgtgctggcctaccgtaaatcgcagcaacactga
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